KEGG   DGROUP: Simeprevir
Entry
DG01246           Chemical  DGroup                                 

Name
Simeprevir
Member
D10081  
Simeprevir (JAN/USAN)
D10469  
Simeprevir sodium (JAN)
Class
Antiviral
 DG02001  NS3/4A inhibitor
Metabolizing enzyme substrate
 DG01633  CYP3A substrate
Metabolizing enzyme inhibitor
 DG02852  CYP3A inhibitor
Transporter substrate
 DG01665  ABCB1 (P-GP) substrate
 DG02856  SLCO1B1 (OATP1B1) substrate
Transporter inhibitor
 DG01622  ABCB1 (P-GP) inhibitor
 DG02862  ABCG2 (BCRP) inhibitor
 DG02865  SLCO1B1 (OATP1B1) inhibitor
Remark
ATC code: J05AP05
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