KEGG   Delphinapterus leucas (beluga whale): 111164342
Entry
111164342         CDS       T05885                                 

Gene name
TGFBR2
Definition
(RefSeq) TGF-beta receptor type-2
  KO
K04388  TGF-beta receptor type-2 [EC:2.7.11.30]
Organism
dle  Delphinapterus leucas (beluga whale)
Pathway
dle04010  MAPK signaling pathway
dle04060  Cytokine-cytokine receptor interaction
dle04068  FoxO signaling pathway
dle04144  Endocytosis
dle04218  Cellular senescence
dle04350  TGF-beta signaling pathway
dle04380  Osteoclast differentiation
dle04390  Hippo signaling pathway
dle04520  Adherens junction
dle04659  Th17 cell differentiation
dle04926  Relaxin signaling pathway
dle04933  AGE-RAGE signaling pathway in diabetic complications
dle05142  Chagas disease
dle05161  Hepatitis B
dle05166  Human T-cell leukemia virus 1 infection
dle05200  Pathways in cancer
dle05202  Transcriptional misregulation in cancer
dle05210  Colorectal cancer
dle05212  Pancreatic cancer
dle05220  Chronic myeloid leukemia
dle05225  Hepatocellular carcinoma
dle05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:dle00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    111164342 (TGFBR2)
   04350 TGF-beta signaling pathway
    111164342 (TGFBR2)
   04390 Hippo signaling pathway
    111164342 (TGFBR2)
   04068 FoxO signaling pathway
    111164342 (TGFBR2)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    111164342 (TGFBR2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    111164342 (TGFBR2)
  09143 Cell growth and death
   04218 Cellular senescence
    111164342 (TGFBR2)
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    111164342 (TGFBR2)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    111164342 (TGFBR2)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    111164342 (TGFBR2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    111164342 (TGFBR2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    111164342 (TGFBR2)
   05202 Transcriptional misregulation in cancer
    111164342 (TGFBR2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    111164342 (TGFBR2)
   05212 Pancreatic cancer
    111164342 (TGFBR2)
   05225 Hepatocellular carcinoma
    111164342 (TGFBR2)
   05226 Gastric cancer
    111164342 (TGFBR2)
   05220 Chronic myeloid leukemia
    111164342 (TGFBR2)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    111164342 (TGFBR2)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    111164342 (TGFBR2)
   05161 Hepatitis B
    111164342 (TGFBR2)
  09174 Infectious disease: parasitic
   05142 Chagas disease
    111164342 (TGFBR2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:dle01001]
    111164342 (TGFBR2)
Enzymes [BR:dle01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.30  receptor protein serine/threonine kinase
     111164342 (TGFBR2)
Protein kinases [BR:dle01001]
 Receptor serine/threonine kinases (RSTK): TKL group
  TGFBR2 family [OT]
   111164342 (TGFBR2)
SSDB
Motif
Pfam: ecTbetaR2 PK_Tyr_Ser-Thr Pkinase Pkinase_fungal APH
Other DBs
NCBI-GeneID: 111164342
NCBI-ProteinID: XP_022409656
UniProt: A0A2Y9LLN5
LinkDB
Position
Unknown
AA seq 567 aa
MGRGLLGGLWPLHIVLWTRIASTIPPHVPKSVNSDMMVTDDNGAVKLPQLCKFCDVRLST
CDSQKSCWSNCSITAICEKPQEVCVAVWRKNDENVTLETVCHDPKIAYHGFVLDDAASSE
CIMKEKKGSGETFFMCSCSSEECNDHIIFSEEYATNNPDLLLVIFQVTGVSLLPPLGIAI
AVIVTFYCYRVHRQQKLSPAWDSGKPRKLMEFSEHLAIILEDDRSDISSTCANNINHNTE
LLPIELDTLVGKGRFAEVYKAKLRQNTSEQFETVAVKIFPYEEYASWKTEKDIFSDINLK
HENILQFLTAEERKTELGKQYWLITAFHAKGNLQEYLTRHVISWEDLRRLGGSLARGIAH
LHSDHTLCGRPKMPIVHRDLKSSNILVKGDLTCCLCDFGLSLRLDPTLSVDDLANSGQVG
TARYMAPEVLESRMNLENVESFKQTDVYSMALVLWEMTSRCSAVGEVKDYEPPFGSKVRE
HPCVESMKDNVLRDRGRPEIPSSWLNHQGIQTVCETLAECWDHDPEARLTAQCVAERFSE
LEHLDRLSGRSSSEEKIPEDGSLNTTK
NT seq 1704 nt   +upstreamnt  +downstreamnt
atgggccgggggctgcttgggggcctgtggccgctgcacatcgtcctgtggacacgcatc
gccagcacgatcccgcctcacgttcccaagtcggttaacagtgacatgatggtcactgac
gacaatggtgccgtcaagttgccgcagttgtgtaaattctgtgatgtgagattgtccacc
tgtgacagccagaagtcctgctggagcaactgcagcatcacggccatctgtgagaagccg
caagaggtctgcgtggctgtctggagaaagaatgatgagaacgtcacactggagacggtc
tgccacgaccccaagatcgcctaccatggatttgtccttgacgacgctgcttcttcagag
tgtataatgaaggaaaaaaaggggtctggagagactttcttcatgtgttcctgcagctcc
gaagagtgcaacgaccacatcatcttctccgaagaatacgccaccaacaaccccgacttg
ctgttggtcatcttccaagtgacaggtgtcagcctcctgccaccgctgggcatcgccatt
gctgtcattgtcaccttctactgctaccgcgtccaccggcagcagaagctgagcccggcc
tgggactcgggcaagccgcgcaagctgatggagttcagtgagcacctggccatcatcctg
gaggatgaccgctccgacatcagctccacctgtgccaacaacatcaatcacaacacggag
ttgctgcccattgagctggacaccctggtgggcaaagggcgcttcgccgaggtctacaag
gccaagctgaggcagaacacgtctgagcagtttgagaccgtggccgtcaagatcttcccc
tatgaagaatatgcctcctggaagacggagaaggacatcttctcggacatcaacctcaag
cacgagaacatcctgcagttcctgacagctgaggagcgcaagacggagctgggcaagcag
tactggctgatcaccgccttccacgccaagggcaacctgcaggagtacctgacgcgccac
gtcatcagctgggaggacctgcgcaggctgggcggctcactggcccgtggcatcgcgcac
ctgcacagtgaccacacgctgtgcggccgacccaagatgcccatcgtgcacagggacctc
aagagctccaacatcctggtcaagggagacctcacctgctgcctctgtgacttcggcctc
tccctgcggctggaccccactctgtctgtggatgacctggccaacagtgggcaggtggga
acggcgagatacatggctccagaggtcctcgagtccaggatgaatctggagaatgtcgag
tccttcaagcagacagatgtctactccatggccctggtgctctgggagatgacgtctcgc
tgcagcgcagtgggagaagtgaaggattatgagcctccattcggttccaaggtgcgggag
catccctgtgtcgaaagcatgaaggacaacgtgttgagagatcgaggacgacccgaaatc
ccaagctcctggctcaaccaccagggcatccagacggtgtgtgagacgctggccgagtgc
tgggaccacgaccccgaggcccggctcacggcgcagtgtgtggccgagcgcttcagtgag
ctggagcatctggacagactctcgggcaggagcagttcggaggagaagattcccgaagac
ggctccctgaacactaccaaatag

DBGET integrated database retrieval system