Delphinapterus leucas (beluga whale): 111166258
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Entry
111166258 CDS
T05885
Gene name
BRCA1
Definition
(RefSeq) breast cancer type 1 susceptibility protein isoform X1
KO
K10605
breast cancer type 1 susceptibility protein [EC:
2.3.2.27
]
Organism
dle
Delphinapterus leucas (beluga whale)
Pathway
dle01524
Platinum drug resistance
dle03440
Homologous recombination
dle03460
Fanconi anemia pathway
dle04120
Ubiquitin mediated proteolysis
dle04151
PI3K-Akt signaling pathway
dle05206
MicroRNAs in cancer
dle05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
dle00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
111166258 (BRCA1)
09124 Replication and repair
03440 Homologous recombination
111166258 (BRCA1)
03460 Fanconi anemia pathway
111166258 (BRCA1)
09130 Environmental Information Processing
09132 Signal transduction
04151 PI3K-Akt signaling pathway
111166258 (BRCA1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
111166258 (BRCA1)
09162 Cancer: specific types
05224 Breast cancer
111166258 (BRCA1)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
111166258 (BRCA1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
dle01009
]
111166258 (BRCA1)
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
dle04121
]
111166258 (BRCA1)
03036 Chromosome and associated proteins [BR:
dle03036
]
111166258 (BRCA1)
03400 DNA repair and recombination proteins [BR:
dle03400
]
111166258 (BRCA1)
Enzymes [BR:
dle01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.27 RING-type E3 ubiquitin transferase
111166258 (BRCA1)
Protein phosphatases and associated proteins [BR:
dle01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
111166258 (BRCA1)
Ubiquitin system [BR:
dle04121
]
Ubiquitin ligases (E3)
Single Ring-finger type E3
Other single Ring-finger type E3
111166258 (BRCA1)
Multi subunit Ring-finger type E3
BRCC complex
111166258 (BRCA1)
Chromosome and associated proteins [BR:
dle03036
]
Eukaryotic type
Centrosome formation and ciliogenesis proteins
Centrosome duplication proteins
Regulators of centriole replication
111166258 (BRCA1)
DNA repair and recombination proteins [BR:
dle03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
BRCA1-core complex
111166258 (BRCA1)
BRCA1-A complex
111166258 (BRCA1)
BRCA1-B complex
111166258 (BRCA1)
BRCA1-C complex
111166258 (BRCA1)
BRCA complex
111166258 (BRCA1)
FA (Fanconi anemia) pathway
Downstream FA components
111166258 (BRCA1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
BRCT_assoc
BRCT
zf-C3HC4
zf-C3HC4_2
zf-C3HC4_4
zf-C3HC4_3
zf-RING_2
zf-RING_UBOX
zf-RING_5
BRCT_2
zf-Nse
zf-RING_6
zf-ANAPC11
Prok-RING_4
zf-RING_10
zf-rbx1
Motif
Other DBs
NCBI-GeneID:
111166258
NCBI-ProteinID:
XP_022413471
UniProt:
A0A2Y9LXF5
LinkDB
All DBs
Position
Unknown
AA seq
1866 aa
AA seq
DB search
MDFSANHVEEVQNVLNAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ
CPLCKNDITRRSLQESTRFSQLVEELLKIIHAFELDTGLQIANSYNFSKKENNSPEHLKE
EVSIIQSMGYRNRTKRLQQSEPENPTLQETSLSVQLSNLGIVRSLRTEQQIQPQNKSVYI
ELGSDSSEDTVNKASYFSVEDHELLEITPQGAKAEASLNRAKNAACEFSEKDITKAEHHQ
FSNKDLTTTEKHETEKHPEKYQGIFVSNLHVEPCGTDTHASSLQHENSSLLLTKDRMNVE
KAEFCNKSKQLVLGKSQQSRWAESKDTCNDRQTPSTEKKVVLNADPLYGRKELNKQKPAS
SDSPRDSQEFPWITLNSSIQKVNEWFSRSDEMLTSYDSRDGGFESNTEVARAVEVPKEVD
GYLGSSEKIDLMASDPHGALIRERVHAKPVESNIEDKIFGKTYQRKASLPNLSRIAEDLI
IGASTVEPQITQERPLTKKLKRKRRSTSGLHPEDFIKKVDLAVLPKTPENIIEGTDQTEQ
NGHGMNITSNGHETEMKGGYVQKEKNANRTESLEKESAFRTKAEPISSSISNMELELNIH
SSKAPKNRLRRKSSTRNIHALELVVSRNPSPPNHTELQIDSCSSSEEMKKKHSSQMPVRH
GKKLQFMGDKEPTTGAKKSDKPHEQITKRLASDTYPELNLTNIPVFFTHCSSSNKLQEFV
NPSLQREESLGTIQVSNNTKDPQDLTLSGGKGLQIERCVESTNISLVPDTDYGTQDSISL
LEADTLGKAKTAPNQHVSLCAAIESPKELIPGCSKDIRNDTEDFQDPLGHDVNHIQKASI
EMEESELDTQYLQNMFKVSKRQTFALFSNPENPEKECATVCAHSGSLREQSPRVPLECRQ
KEENQGKSESKIKHVRAINTTVDFPVAGQKDKKPSDHAKRSPERVTRLCQSSQFRGNKTE
LIIANKHGISHSPYLIPSLSPIRSSIKTMCKKNLSEEKFEEPVMSPERAVENESIVQSTV
RTISQNNSRESTFKEVSSSSINEVGSSTNEVGSSINEVGSSGENIQAKLDRNRGPKLSAL
LRLGLMQPEVYKQSLPVSNCQLPEIKRQGENEGTLQAVNEDFSPCLNSDNLEQPMGRSHA
SQVCSETPDELLNDDKIKESSNFAESDIKERSAVFSKSVQKGEFRRSPGPLAHHTSLVQG
HERGAESSEENVSSEDEELPCFQHLFGKVTNTLSPSTRRNAVATEGLSKETEENLISLKN
SLNDCSDHVTSAKASQEHHLHEEARCSDSLFSSRCSAVEDLTANTNTQDPFLMFDPLSKQ
VGHQSENQEVLSGKELVSDDDEREAGWEEDNRQDEQSVDSDLGEAASEYESETSLSEDCL
GLSSQSDILTTQQRDTMQDNLLKIQQEMAELEAVLEQHGSQPSHSSPSLIADSCASEDLL
NLEQNTSEKAVLTSEKSSEYPISRNPESLSADKFQVSPDTSTSKNKEPGMERSSPSKSQL
SDNSWYMHSHSRSLQNRNCPPQKELEVVDVEEQQLTESEAQDLMEQSSLPRQDLEGTPYL
ESGISLFSDDPESDPSEDRAPEPAHVCSMPPSASALKLPQFQVVESARSPAAAHATNTAG
YNVREESVSREKPELISSTQRGNKRISMVASGLTPKEFVLVHKFARKHHITLTNLITEET
THVIMKTDAEFVCERTLKYFLGIAGGKWVVSYFWVTQSIKERKMLDEHDFEVRGDVVNGR
NHQGPKRARESQDRKIFKGLEICCYGPFTNMPTDQLEWMVHLCGASVVKEPSSFTLSQGT
QPIVVVQPDAWTEGGGFRVIGQMCEAPVVTREWVLDSVALYQCQELDTYLISQVPRAAAD
SSLPCI
NT seq
5601 nt
NT seq
+upstream
nt +downstream
nt
atggatttttctgcgaatcacgttgaagaagtacaaaatgtccttaatgctatgcagaaa
atcttagagtgtccaatctgtctggagttgatcaaagagcctgtttccacaaagtgtgat
cacatattttgcaaattttgtatgctgaaacttctcaaccagaagaaagggccttcacag
tgtcctttgtgtaagaatgatataaccagaagaagcctgcaagaaagtacaagatttagt
cagcttgttgaagagctattgaagatcattcatgcttttgagcttgacacaggattgcag
attgcaaacagttataacttttcaaaaaaggaaaataactctcctgagcatctaaaggag
gaagtttctatcattcaaagtatgggctaccgaaaccggaccaaaagacttcaacagagt
gaacctgaaaatcctaccttgcaggaaaccagtcttagtgtccagctctctaaccttgga
attgtgagatctctgaggacagagcagcagatacaacctcaaaataagtccgtctacatt
gaattgggatctgattcttctgaagatacagttaataaggccagttatttcagtgtagaa
gaccatgaattgttagaaatcacccctcaaggagccaaggctgaagccagtttgaatcgt
gcaaaaaacgctgcttgtgagttttctgagaaggacataacaaaggctgaacatcatcag
ttcagtaacaaagatttgaccaccactgagaagcatgaaactgagaagcatccagaaaag
tatcagggtatttttgtttcaaacttgcatgtggagccatgtggcacagatactcatgcc
agctcattacagcatgaaaacagcagtttattactcactaaagacagaatgaatgtagaa
aaggctgaattctgtaataaaagcaaacagcttgtcttaggaaagagccaacagagcaga
tgggctgaaagtaaggacacatgtaatgataggcagactcccagtacagagaaaaaggta
gttctgaatgctgatcccctatatgggagaaaagaactgaataagcagaaacctgcgtcc
tctgacagtcctagagattcccaagagtttccttggataacactgaatagtagcatacag
aaagttaatgaatggttttccagaagtgatgaaatgttaacttcttacgactcacgtgat
gggggatttgaatcaaacactgaagtagctcgtgcagtggaagttccaaaggaagttgat
ggatatttgggttcttcagagaaaatagacttaatggccagtgatcctcacggtgcttta
atacgtgaaagagtccacgccaaaccagtagagagtaatattgaagataaaatatttggg
aaaacctatcagaggaaggcaagcctccctaacttgagccgcatagctgaagatctaatt
ataggagcatctactgtagaacctcagataacacaagagcgccccctcacaaaaaaacta
aagcgtaaaaggagaagtacatcaggccttcatcctgaggattttatcaagaaagtcgat
ttggcagttcttccaaagactccagaaaacataattgagggaactgaccaaacagagcag
aatggtcatgggatgaatattactagtaatggtcatgagactgaaatgaaaggtggttat
gttcagaaagagaaaaatgctaaccgaacagaatcattggaaaaagaatctgctttcaga
actaaggctgaacctataagcagcagtataagcaatatggaactagaattgaatatccat
agttcaaaagcacctaaaaataggctgaggaggaagtcctctaccaggaacattcatgca
cttgaactagtagtcagtagaaacccaagcccacctaatcatactgaactacaaattgat
agttgttctagcagtgaagagatgaagaaaaaacattccagccaaatgccagtcaggcac
ggcaaaaagcttcaattcatgggagataaagaacctacaactggagccaagaagagtgac
aagccacacgaacaaataactaagagacttgccagtgacacttacccagaactaaatttg
acaaacatacctgttttttttactcactgttccagttctaataaacttcaagagtttgtt
aatcctagccttcaaagagaggagagcctaggaacaattcaagtgtcgaataataccaaa
gacccccaagatctgacattaagtggaggaaaaggtttgcaaattgaaagatgtgtagag
agtaccaatatttccttggtacctgatactgattatggcactcaggatagtatttcatta
ctggaagctgacaccctagggaaggcaaagacagcaccaaatcaacatgtgagtctgtgt
gcagcaattgaaagccccaaggaacttatccctggttgttctaaagatattagaaacgac
acagaggactttcaggatccactgggacatgacgttaaccacattcagaaggcgagcata
gaaatggaagagagtgaacttgatacacagtatttgcagaatatgttcaaggtttcaaag
cgtcagacgtttgctctgttttcaaatccagaaaatccagaaaaggaatgtgcaacagtc
tgtgcccactctgggtccttaagggaacaaagtccaagagtccctcttgaatgcagacaa
aaagaagaaaatcagggaaagagtgagtctaaaatcaagcatgtgcgggcaattaataca
actgtggacttccctgtcgctggtcaaaaagataagaagccgagcgatcatgccaaacgt
agcccagaaagagtaactaggctttgtcagtcatcacagttcagaggcaacaaaactgag
ctcattattgcaaataaacatgggatttcacacagcccatatcttataccatcactttct
cccatcaggtcatctattaaaactatgtgtaagaaaaacctgtcagaggaaaagtttgag
gaacctgtaatgtcacctgaaagagcagtggaaaacgagagcatcgttcaaagtacagtg
cgcacaattagccaaaataacagtcgagaaagcacttttaaagaagtcagctcaagcagt
attaatgaagtaggttccagtactaatgaagtaggctctagtattaatgaagtaggttcc
agtggtgaaaacattcaagcaaaactagatagaaacagaggacctaaattaagtgctttg
ctcagattaggtcttatgcaacccgaagtctataagcaaagtcttcctgtaagtaactgt
caacttcctgaaataaaaaggcaaggagaaaatgaaggcacacttcaggctgttaatgaa
gatttctccccatgtctaaattcagataacctagaacaacctatgggaagaagccacgct
tctcaggtttgttctgagacacctgatgagttgttaaatgatgacaaaataaaggaaagt
agcaactttgctgaaagtgacattaaggaaagatctgctgtttttagcaaaagtgtccaa
aaaggagaattcagaaggagccctggccctttagcccatcatacatctttggttcagggt
cacgaaagaggggctgagtcctcagaagagaatgtttctagtgaggatgaagagcttccc
tgcttccaacacttatttggtaaagtaaccaatacactgtctccatctaccagacgtaat
gctgttgccacggagggtctatctaaggaaacagaggagaatctaatatcattgaagaat
agtttaaatgactgcagtgaccacgtaacatcggcaaaggcatcccaggaacatcacctt
catgaggaagcgagatgttctgatagcttattttcttcacggtgcagtgcagtggaagac
ttgaccgctaatacaaacacccaggatcctttcttgatgtttgatcctctttccaaacaa
gtggggcatcagtctgaaaaccaggaagttctgagtggcaaggaattggtttcagatgat
gatgaaagggaagctggctgggaagaggataatcgccaagacgagcagagtgtggattca
gacttaggtgaagcagcatccgagtatgagagtgaaacaagcctctctgaagactgtttg
gggctgtcctctcagagcgatatcttaaccactcagcagagggataccatgcaagataac
ctgctaaagatccagcaggaaatggccgaactggaagctgtgttagagcagcacgggagc
cagccttctcacagctccccttccctcatagccgattcttgtgcctctgaggacctgcta
aatctggaacaaaacacatcagaaaaagcagtattaacttcagagaaaagtagtgaatat
cctataagccggaatccagaaagcctttctgctgacaagtttcaagtatctccggatact
tccaccagtaaaaataaagaaccaggaatggaaaggtcttccccttctaaatcacagttg
tcagataatagttggtatatgcacagccactcaaggagtcttcagaacagaaactgccca
cctcaaaaggagcttgaggttgttgatgtggaggagcaacagctgacggagtctgaggcc
caggatttaatggagcagtcttctttgccaagacaagatctagagggaaccccttaccta
gaatctggaatcagcctcttctctgatgaccctgagtctgatccctctgaagacagagcc
ccagagccagctcatgtctgcagcatgccaccctcagcctctgcactgaaattaccccaa
tttcaagtagtagaatctgccaggagtccggctgcagctcatgctactaatactgcaggg
tataatgtgcgggaagaaagtgtgagcagggagaagccagagttgatatcttcaacacaa
agaggcaacaaaagaatttctatggtggcatcaggcttgaccccaaaagaatttgtgctt
gtgcacaagtttgccagaaaacatcacatcactttaactaatctaattactgaagagact
actcatgtcattatgaaaacagatgccgagtttgtgtgtgaacggacactgaaatatttc
ctggggatcgcaggaggaaaatgggtagttagctatttctgggtgacccagtctattaaa
gaaagaaagatgctggatgagcatgattttgaagtcagaggcgatgttgtcaatggaaga
aaccatcaaggcccaaagcgagcaagagaatcccaggacaggaagatcttcaagggctta
gaaatctgttgctatggaccgtttaccaatatgcccacagatcaactagagtggatggtg
catctgtgtggggcttctgtggtgaaggagccctcatcattcaccctcagccagggtact
caaccaattgtggtcgtgcagccagatgcctggacagagggcggtggcttccgtgtcatc
gggcagatgtgtgaagcacctgtggtgacccgagagtgggtattggacagcgtagccctc
taccagtgccaggagctggacacctacctgatatcccaggtccccagagctgctgctgat
tccagcctgccatgtatatag
DBGET
integrated database retrieval system
