KEGG   Delphinapterus leucas (beluga whale): 111166491
Entry
111166491         CDS       T05885                                 

Gene name
STAT3
Definition
(RefSeq) signal transducer and activator of transcription 3 isoform X1
  KO
K04692  signal transducer and activator of transcription 3
Organism
dle  Delphinapterus leucas (beluga whale)
Pathway
dle01521  EGFR tyrosine kinase inhibitor resistance
dle04062  Chemokine signaling pathway
dle04066  HIF-1 signaling pathway
dle04068  FoxO signaling pathway
dle04217  Necroptosis
dle04550  Signaling pathways regulating pluripotency of stem cells
dle04630  JAK-STAT signaling pathway
dle04659  Th17 cell differentiation
dle04917  Prolactin signaling pathway
dle04920  Adipocytokine signaling pathway
dle04931  Insulin resistance
dle04933  AGE-RAGE signaling pathway in diabetic complications
dle04935  Growth hormone synthesis, secretion and action
dle05145  Toxoplasmosis
dle05160  Hepatitis C
dle05161  Hepatitis B
dle05162  Measles
dle05163  Human cytomegalovirus infection
dle05167  Kaposi sarcoma-associated herpesvirus infection
dle05169  Epstein-Barr virus infection
dle05200  Pathways in cancer
dle05203  Viral carcinogenesis
dle05205  Proteoglycans in cancer
dle05206  MicroRNAs in cancer
dle05212  Pancreatic cancer
dle05221  Acute myeloid leukemia
dle05223  Non-small cell lung cancer
dle05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
dle05321  Inflammatory bowel disease
Brite
KEGG Orthology (KO) [BR:dle00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    111166491 (STAT3)
   04066 HIF-1 signaling pathway
    111166491 (STAT3)
   04068 FoxO signaling pathway
    111166491 (STAT3)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    111166491 (STAT3)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    111166491 (STAT3)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    111166491 (STAT3)
   04062 Chemokine signaling pathway
    111166491 (STAT3)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    111166491 (STAT3)
   04917 Prolactin signaling pathway
    111166491 (STAT3)
   04935 Growth hormone synthesis, secretion and action
    111166491 (STAT3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    111166491 (STAT3)
   05206 MicroRNAs in cancer
    111166491 (STAT3)
   05205 Proteoglycans in cancer
    111166491 (STAT3)
   05203 Viral carcinogenesis
    111166491 (STAT3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    111166491 (STAT3)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    111166491 (STAT3)
   05221 Acute myeloid leukemia
    111166491 (STAT3)
   05223 Non-small cell lung cancer
    111166491 (STAT3)
  09163 Immune disease
   05321 Inflammatory bowel disease
    111166491 (STAT3)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    111166491 (STAT3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    111166491 (STAT3)
  09172 Infectious disease: viral
   05162 Measles
    111166491 (STAT3)
   05161 Hepatitis B
    111166491 (STAT3)
   05160 Hepatitis C
    111166491 (STAT3)
   05163 Human cytomegalovirus infection
    111166491 (STAT3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    111166491 (STAT3)
   05169 Epstein-Barr virus infection
    111166491 (STAT3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    111166491 (STAT3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    111166491 (STAT3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:dle03000]
    111166491 (STAT3)
Transcription factors [BR:dle03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    111166491 (STAT3)
SSDB
Motif
Pfam: STAT_alpha STAT_bind STAT_int SH2 E2R135 DUF4795 Syntaxin-6_N AP1AR Baculo_PEP_C Fib_alpha
Other DBs
NCBI-GeneID: 111166491
NCBI-ProteinID: XP_022413945
UniProt: A0A2Y9LX05
LinkDB
Position
Unknown
AA seq 770 aa
MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNL
LGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAA
TAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLK
SQGDMQDLNGNSQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEEL
ADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQ
HRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNY
QLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGN
GGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWY
NMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYS
GCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILST
KPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIM
DATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGSAAPYLKTKFICVTPTTCSN
TIDLPMSPRTLDSLMQFGNNGEGAEPSAGGQFESLTFDMELTSECATSPM
NT seq 2313 nt   +upstreamnt  +downstreamnt
atggcccaatggaatcagctacagcagctggacacacggtacttggagcagcttcatcag
ctgtacagtgacagcttcccgatggagctacggcagtttctagccccttggatcgagagt
caagattgggcatatgcggccagcaaagaatcacatgcaactttggtgtttcataatctc
ttgggtgaaattgaccagcagtatagccgcttcctgcaagagtccaatgttctctatcag
cacaacctgcgaagaatcaagcagttccttcagagcagataccttgagaagccaatggag
attgcccgaattgtggcccggtgcctgtgggaagagtcccgcctcctccaaactgcagcc
actgcagcccagcaagggggccaggccaaccatcccacagccgccgtggtgacggagaag
cagcaaatgctggagcaacacctgcaggatgtccggaagcgtgtccaggatctagaacag
aaaatgaaagtggtagagaatctccaggatgactttgatttcaactacaaaaccctcaag
agtcaaggagacatgcaagacctgaatggaaacagccagtcagtgaccaggcagaagatg
cagcagctcgagcaaatgcttaccgcgctggaccagatgcggcgaagcatcgtgagtgag
ttggcagggcttttgtcagctatggagtacgtacagaaaactctcacggatgaagagctg
gcggactggaagaggcggcagcagattgcttgcattggaggccctcccaacatctgccta
gatcggctagaaaactggataacctcattggcagaatctcaacttcagacccgccaacaa
attaagaaactggaggagttgcagcagaaagtgagctacaaaggggatcccattgtacag
caccggccaatgctggaggagagaatcgtagagctgtttagaaacttaatgaaaagtgcc
ttcgtggtagagcggcagccctgcatgcctatgcatcccgaccggccattagtcatcaag
accggtgtccagtttacaactaaagtcagattgctggtcaaatttcctgagctaaattat
cagcttaaaattaaagtgtgcattgacaaagactccggggatgttgcagctctcagagga
tcccggaaatttaacatcctgggcacaaacacgaaagtgatgaacatggaagagtctaac
aacggcagcctctccgcagagttcaaacacttgaccctgagagagcagagatgtggtaac
gggggccgagccaactgcgacgcctccctgattgtgactgaagagctgcacctgatcacc
tttgagactgaggtgtatcaccaaggcctcaagattgacctagagacccactccttgcca
gttgtggtgatctccaacatctgtcagatgcccaacgcctgggcatccatcctgtggtat
aacatgctgaccaacaaccccaagaacgtgaactttttcaccaagcccccaattggaacg
tgggatcaagtggccgaggtgctgagctggcagttctcctccaccaccaagcgcgggctg
agcatcgagcagttgacaacgctggcggagaaactcttaggacctggtgtgaactattca
gggtgtcagatcacgtgggctaaattttgcaaagaaaacatggccggcaagggcttctcc
ttctgggtctggctggacaatatcattgaccttgtgaaaaagtacatcctggccctttgg
aatgaagggtacataatgggctttatcagtaaggagagggagcgggccatcttgagcacc
aagcccccaggcaccttcctgctgagattcagtgaaagcagcaaagaaggaggagtcacc
ttcacttgggtggagaaggacatcagcggtaagacccagatccagtcggtggaaccatac
accaagcagcagctgaacaacatgtcgtttgctgaaatcatcatgggctataagatcatg
gatgccaccaacatcctcgtgtctccgctggtctatctctaccctgacattccaaaggag
gaggcgttcggaaagtactgccggccagagagccaggagcatcccgaagctgacccaggt
agtgctgccccatacctgaagactaagttcatctgtgtgacaccaacgacctgcagcaat
accattgacctgccgatgtccccccgcactttagattcattgatgcagtttggaaataat
ggtgaaggtgctgaaccctcagcaggagggcaatttgaatccctcacgttcgacatggag
ctgacctcggagtgcgctacctcccccatgtga

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