KEGG   Delphinapterus leucas (beluga whale): 111169371
Entry
111169371         CDS       T05885                                 

Gene name
PDGFA
Definition
(RefSeq) platelet-derived growth factor subunit A
  KO
K04359  platelet-derived growth factor subunit A
Organism
dle  Delphinapterus leucas (beluga whale)
Pathway
dle01521  EGFR tyrosine kinase inhibitor resistance
dle04010  MAPK signaling pathway
dle04014  Ras signaling pathway
dle04015  Rap1 signaling pathway
dle04020  Calcium signaling pathway
dle04072  Phospholipase D signaling pathway
dle04151  PI3K-Akt signaling pathway
dle04510  Focal adhesion
dle04540  Gap junction
dle04630  JAK-STAT signaling pathway
dle04810  Regulation of actin cytoskeleton
dle05200  Pathways in cancer
dle05202  Transcriptional misregulation in cancer
dle05206  MicroRNAs in cancer
dle05214  Glioma
dle05215  Prostate cancer
dle05218  Melanoma
dle05231  Choline metabolism in cancer
dle05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:dle00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    111169371 (PDGFA)
   04014 Ras signaling pathway
    111169371 (PDGFA)
   04015 Rap1 signaling pathway
    111169371 (PDGFA)
   04630 JAK-STAT signaling pathway
    111169371 (PDGFA)
   04020 Calcium signaling pathway
    111169371 (PDGFA)
   04072 Phospholipase D signaling pathway
    111169371 (PDGFA)
   04151 PI3K-Akt signaling pathway
    111169371 (PDGFA)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    111169371 (PDGFA)
   04540 Gap junction
    111169371 (PDGFA)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    111169371 (PDGFA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    111169371 (PDGFA)
   05202 Transcriptional misregulation in cancer
    111169371 (PDGFA)
   05206 MicroRNAs in cancer
    111169371 (PDGFA)
   05231 Choline metabolism in cancer
    111169371 (PDGFA)
  09162 Cancer: specific types
   05214 Glioma
    111169371 (PDGFA)
   05218 Melanoma
    111169371 (PDGFA)
   05215 Prostate cancer
    111169371 (PDGFA)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    111169371 (PDGFA)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    111169371 (PDGFA)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:dle04052]
    111169371 (PDGFA)
   00536 Glycosaminoglycan binding proteins [BR:dle00536]
    111169371 (PDGFA)
Cytokines and growth factors [BR:dle04052]
 Growth factors
  Growth factors (RTK binding)
   111169371 (PDGFA)
Glycosaminoglycan binding proteins [BR:dle00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   111169371 (PDGFA)
SSDB
Motif
Pfam: PDGF_N PDGF
Other DBs
NCBI-GeneID: 111169371
NCBI-ProteinID: XP_022419239
UniProt: A0A2Y9MAM4
LinkDB
Position
Unknown
AA seq 196 aa
MRTWACLLLLGCGYLASALAEEAEIPREVIERLAHSQIHSIRDLQRLLEIDSVGAEEPLE
TSLRAHGGRGAKHALEKRPVPIRRKRSIEEAIPAVCKTRTVIYEIPRSQVDPTSANFLIW
PPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECTCA
SVSPSPGHREEEADVR
NT seq 591 nt   +upstreamnt  +downstreamnt
atgaggacctgggcttgtttgctgctcctcggctgcggatacctcgccagtgccctggcc
gaggaagccgagatcccccgcgaggtcattgagaggctggcgcacagtcagatacacagc
atccgggacctccagcgactcctggagatagactccgtaggggccgaggagcctttggag
accagcctgagagcccacgggggccgtggcgccaagcatgcactggagaagcggcctgtg
cccattcggaggaaaagaagcatcgaggaagccatccccgcagtctgcaagaccaggacg
gtcatttatgagatacctcggagccaggtggaccccacgtctgccaactttctgatctgg
cccccgtgcgtggaggtgaagcgctgtaccggctgctgcaacaccagcagtgtcaagtgc
caaccatcccgcgtccaccaccggagtgtcaaggtggccaaggtggagtacgtcaggaag
aagccaaagttaaaagaggtgcaggtgcggctggaggagcacctggaatgcacgtgcgcg
agcgtcagcccgagccccggccaccgggaagaggaggcggatgtgaggtga

KEGG   Delphinapterus leucas (beluga whale): 111186135
Entry
111186135         CDS       T05885                                 

Gene name
EGF
Definition
(RefSeq) pro-epidermal growth factor
  KO
K04357  epidermal growth factor
Organism
dle  Delphinapterus leucas (beluga whale)
Pathway
dle01521  EGFR tyrosine kinase inhibitor resistance
dle04010  MAPK signaling pathway
dle04012  ErbB signaling pathway
dle04014  Ras signaling pathway
dle04015  Rap1 signaling pathway
dle04020  Calcium signaling pathway
dle04066  HIF-1 signaling pathway
dle04068  FoxO signaling pathway
dle04072  Phospholipase D signaling pathway
dle04151  PI3K-Akt signaling pathway
dle04510  Focal adhesion
dle04540  Gap junction
dle04630  JAK-STAT signaling pathway
dle04810  Regulation of actin cytoskeleton
dle05160  Hepatitis C
dle05165  Human papillomavirus infection
dle05200  Pathways in cancer
dle05210  Colorectal cancer
dle05212  Pancreatic cancer
dle05213  Endometrial cancer
dle05214  Glioma
dle05215  Prostate cancer
dle05218  Melanoma
dle05219  Bladder cancer
dle05223  Non-small cell lung cancer
dle05224  Breast cancer
dle05226  Gastric cancer
dle05231  Choline metabolism in cancer
dle05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:dle00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    111186135 (EGF)
   04012 ErbB signaling pathway
    111186135 (EGF)
   04014 Ras signaling pathway
    111186135 (EGF)
   04015 Rap1 signaling pathway
    111186135 (EGF)
   04630 JAK-STAT signaling pathway
    111186135 (EGF)
   04066 HIF-1 signaling pathway
    111186135 (EGF)
   04068 FoxO signaling pathway
    111186135 (EGF)
   04020 Calcium signaling pathway
    111186135 (EGF)
   04072 Phospholipase D signaling pathway
    111186135 (EGF)
   04151 PI3K-Akt signaling pathway
    111186135 (EGF)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    111186135 (EGF)
   04540 Gap junction
    111186135 (EGF)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    111186135 (EGF)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    111186135 (EGF)
   05231 Choline metabolism in cancer
    111186135 (EGF)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    111186135 (EGF)
  09162 Cancer: specific types
   05210 Colorectal cancer
    111186135 (EGF)
   05212 Pancreatic cancer
    111186135 (EGF)
   05226 Gastric cancer
    111186135 (EGF)
   05214 Glioma
    111186135 (EGF)
   05218 Melanoma
    111186135 (EGF)
   05219 Bladder cancer
    111186135 (EGF)
   05215 Prostate cancer
    111186135 (EGF)
   05213 Endometrial cancer
    111186135 (EGF)
   05224 Breast cancer
    111186135 (EGF)
   05223 Non-small cell lung cancer
    111186135 (EGF)
  09172 Infectious disease: viral
   05160 Hepatitis C
    111186135 (EGF)
   05165 Human papillomavirus infection
    111186135 (EGF)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    111186135 (EGF)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:dle04052]
    111186135 (EGF)
Cytokines and growth factors [BR:dle04052]
 Growth factors
  Growth factors (RTK binding)
   111186135 (EGF)
SSDB
Motif
Pfam: Ldl_recept_b FXa_inhibition cEGF EGF_CA EGF EGF_3 DUF5050 Plasmod_Pvs28 Tr-sialidase_C
Other DBs
NCBI-GeneID: 111186135
NCBI-ProteinID: XP_030615977
LinkDB
Position
Unknown
AA seq 1157 aa
MLLFLIILLPVVFKFSFVSLSARQRWSCPEGSPSGNGNSTCVGPAPFLIFSHGNRIFRID
LEGTNHEQLVADAGMSMIMDFHYNEERIYWVDLERQLLQRVFLNGTSQEKICEIEKNVSG
MAINWINEELIWSNQQEGIITVTDMKGNNSRVLLSALKYPANIAVDPVERFMFWSSEVAG
SLHRADLGGVEVKLLLETSEKITAVSLDVLEKRLFWIQYHRERSNSRICSCDYDGGSVHF
SQHHTQHNIFAMSLFGDRIFYSTWKKKTIWIANKYTGKNMVKINLSPSFVPGGIKVVHPL
VQPKAEGDPWVPDQKLCKLRKGNCRSSMCGQEPKSHVCMCAEGYALSQDGKNCEDVNECA
FWNHGCTLGCENIPGSYYCTCPVGFVLLPDGKRCHQLISCPSNVSECSHDCVLTSDGPIC
FCPEGSVLETDGKTCSGCSSPDNGGCSQLCTPLSPVSWECGCIPGYDLQLDKKSCTASGP
PPFLLFANSQDIRHMHFDGTDYGTLLSQQIGMVFALDHDPVENKIYFAHTALKWIERANM
DGSQRERLIEEEVGVPEGLAVDWIGRKFYWTDRRKSLIEGSDLNGKYREIIIKEDISQPR
GLAVHPMAKRLFWTEMGINPRIESSSLQGIGRLVIASSDLVWPSGITIDYLTDKLYWCDA
KQSVIEMSNLDGSKRQRLAQNDVGHPFAVAVFEDHLWFSDWAMPSVIRVNKRTGKNRVCL
RGSMLKPSSLVVVHPLAKPGADACLHQNGGCEHICEERFGTAQCLCREGFVKAPDGKTCL
ALNGHQILAGSGADLSNGVIPLDILPSSREMEDNITESQHMLVAEIMVSDGDDCSALGCS
TQAWCVSEGENVTCRCLKGFAGDGKLCSDIDECQMGISVCPPTSSKCVNTEGGHVCRCSE
GYQGDGIHCLDIDECQLGVHTCGENAACTNTEGNYTCTCAGNSSEPGRICPDSTPPSQPR
EDGRSPVRNIYPECPPSHDGYCLHGGVCMYVEAVDSYACNCVIGYVGERCQHRDLKWWEL
RHAGHGRQRSITAVAACVVVLLLLLLLGLCGAQKYRTQKLLSKNPRNPYEESSRDVSSTR
PVDEEAGMSSYPQPWFVVIEEHQNFSNGSQPVALKDGLVADVGQFSSLEPGSLRPTSWRK
EPQMYMGTEQGCCFIIQ
NT seq 3474 nt   +upstreamnt  +downstreamnt
atgctgctgttccttatcattctgttgccggtagtttttaaatttagttttgtgagcctc
tcagcacggcagcgctggagctgtcctgaaggctctccctcgggaaatgggaattctact
tgtgtgggtcctgcacccttcttaattttctcacatggaaacaggatctttaggattgac
ttggaaggaactaatcatgagcagttggtagcagatgccggcatgtccatgatcatggat
tttcattacaatgaagaaagaatctattgggtcgatctagaaagacaacttttgcaaaga
gtttttctgaatgggacaagccaagagaaaatatgcgagatagagaaaaatgtttcggga
atggcaataaattggatcaatgaagaacttatttggtcaaatcaacaggaaggaatcatt
acagtaacagatatgaaaggaaacaattcccgcgttctcttaagcgccttaaaatatcct
gcaaatatagcagttgatccagtagaaaggtttatgttttggtcttcagaggtggcgggc
agccttcacagagcagatcttggtggtgtggaagtgaagcttctgttagagacatcagag
aaaataacagctgtgtcattggatgtgcttgagaaacggctcttttggattcagtaccat
agagaaagaagcaattctcgtatttgttcctgtgattacgatggaggttccgtccatttt
agccaacatcacacacagcacaatatttttgcgatgtccctttttggtgatcgtattttc
tattcaacatggaaaaagaagacaatttggatagctaacaagtacactgggaagaatatg
gtcaaaattaacctcagtccatcatttgtacctggtggaattaaagtagtgcatccactc
gtacagcccaaggcagagggtgatccttgggtacctgatcagaaactctgcaaactgagg
aaaggtaactgcagaagcagcatgtgtgggcaagagcctaagtcccatgtgtgcatgtgt
gcagagggatatgctttaagccaagatggaaagaactgtgaagatgtcaacgagtgtgcc
ttttggaatcatggctgtactcttgggtgtgaaaacatccctggatcctattattgcaca
tgccctgtaggatttgttctgcttcctgatgggaaacggtgtcaccaattaatttcctgc
ccaagcaatgtgtctgaatgcagtcatgattgtgttctgacatcagacggtcccatatgt
ttctgtcctgaaggctcagtgcttgagacagatgggaaaacctgtagtggttgttcatct
cctgataatggtggatgtagccagctctgcacccctcttagcccagtatcctgggaatgt
ggctgcattccgggctatgacctacaactggacaaaaagagctgtacagcctcaggacca
ccaccgtttttgctgtttgccaattctcaagatattcgacacatgcattttgatggaaca
gattatggaaccctgctcagccagcagataggaatggtttttgccctagatcatgaccct
gtggagaataagatatactttgcccatacagccctaaagtggatagagagagcaaatatg
gatggttcccagcgagaaaggcttattgaggaagaagtaggtgtgccagaaggtcttgct
gtagactggattggccgtaaattctattggacagacagacggaaatctctcattgaaggg
agtgatttaaatgggaagtatcgtgaaataatcattaaggaggacatctctcagccacga
ggacttgctgttcatccaatggccaagagattattctggactgagatggggattaatcca
cgaattgaaagctcttcccttcaaggcattggccgactggttatagctagctcggatctg
gtctggcccagtggaataacaattgattacttaactgacaagttgtattggtgcgatgcc
aagcagtctgtgattgaaatgtccaatctggatggttcaaaacgccaaagacttgcccag
aacgatgtaggtcacccatttgctgtggctgtgtttgaggatcatttgtggttctctgat
tgggctatgccatcggtaataagggtgaacaagaggactggcaaaaatagggtatgtctc
cgaggcagcatgctgaagccctcatcactggttgtagttcatccattggcaaaaccagga
gcagatgcctgcttacatcaaaacggaggctgtgaacatatttgcgaagagaggtttgga
actgctcagtgtttgtgtcgtgaaggttttgtgaaagctccagatggaaaaacgtgtctg
gctctgaatggccatcagatattggcaggtagtggagcagatctgagtaatggagtaata
ccgttggacatcttacccagcagtagagagatggaagataatattacagaatctcagcat
atgctagtggctgaaatcatggtgtcagatggtgacgactgtagtgccttgggatgcagt
acacaggcttggtgtgtttcagagggagagaatgtcacgtgtcggtgtttgaaaggattt
gccggagatggaaaactgtgttctgatatagatgaatgtcagatgggtatttcagtttgc
cctcccacctcctccaagtgcgtcaatactgaaggtggccatgtctgccggtgctcagaa
ggctaccagggagatgggatccactgcctcgatattgatgagtgccaactgggtgtgcac
acctgtggggaaaatgccgcctgtacaaatacggagggaaactacacctgcacatgtgct
ggcaactcatctgaacctggacggatttgccctgactcgactccaccctctcaacccagg
gaggatggccgctctcctgtgagaaatatttaccccgaatgtcccccgtcccacgatggg
tactgcctccatggcggtgtgtgtatgtatgttgaagcggtcgacagctatgcctgcaac
tgtgtcattggctacgtcggggagcgatgtcagcaccgagacttgaagtggtgggaactg
cgccatgccggccatgggcggcagcggagcatcaccgctgtggctgcctgcgtggtggtg
ctgcttctgctgctgctcctggggctgtgcggggctcagaaatacaggactcagaagctg
ctatcgaaaaatccgaggaatccttatgaagagtcgagcagagatgtgagcagtaccagg
cctgtagatgaggaggctgggatgtcctcttacccccaaccttggtttgtggttatagag
gaacatcagaacttcagcaatgggagtcaacctgtagccctcaaggacggcctggtggca
gatgttggccagttttcttccctggagcctgggtcattgcgaccaacatcatggagaaag
gagccccagatgtatatgggcacagaacaaggatgctgtttcatcatccagtga

KEGG   Delphinapterus leucas (beluga whale): 111186344
Entry
111186344         CDS       T05885                                 

Gene name
PDGFB
Definition
(RefSeq) platelet-derived growth factor subunit B isoform X1
  KO
K17386  platelet-derived growth factor subunit B
Organism
dle  Delphinapterus leucas (beluga whale)
Pathway
dle01521  EGFR tyrosine kinase inhibitor resistance
dle04010  MAPK signaling pathway
dle04014  Ras signaling pathway
dle04015  Rap1 signaling pathway
dle04020  Calcium signaling pathway
dle04072  Phospholipase D signaling pathway
dle04151  PI3K-Akt signaling pathway
dle04510  Focal adhesion
dle04540  Gap junction
dle04630  JAK-STAT signaling pathway
dle04810  Regulation of actin cytoskeleton
dle05167  Kaposi sarcoma-associated herpesvirus infection
dle05200  Pathways in cancer
dle05206  MicroRNAs in cancer
dle05211  Renal cell carcinoma
dle05214  Glioma
dle05215  Prostate cancer
dle05218  Melanoma
dle05231  Choline metabolism in cancer
dle05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:dle00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    111186344 (PDGFB)
   04014 Ras signaling pathway
    111186344 (PDGFB)
   04015 Rap1 signaling pathway
    111186344 (PDGFB)
   04630 JAK-STAT signaling pathway
    111186344 (PDGFB)
   04020 Calcium signaling pathway
    111186344 (PDGFB)
   04072 Phospholipase D signaling pathway
    111186344 (PDGFB)
   04151 PI3K-Akt signaling pathway
    111186344 (PDGFB)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    111186344 (PDGFB)
   04540 Gap junction
    111186344 (PDGFB)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    111186344 (PDGFB)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    111186344 (PDGFB)
   05206 MicroRNAs in cancer
    111186344 (PDGFB)
   05231 Choline metabolism in cancer
    111186344 (PDGFB)
  09162 Cancer: specific types
   05214 Glioma
    111186344 (PDGFB)
   05218 Melanoma
    111186344 (PDGFB)
   05211 Renal cell carcinoma
    111186344 (PDGFB)
   05215 Prostate cancer
    111186344 (PDGFB)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    111186344 (PDGFB)
  09172 Infectious disease: viral
   05167 Kaposi sarcoma-associated herpesvirus infection
    111186344 (PDGFB)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    111186344 (PDGFB)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:dle04052]
    111186344 (PDGFB)
   00536 Glycosaminoglycan binding proteins [BR:dle00536]
    111186344 (PDGFB)
Cytokines and growth factors [BR:dle04052]
 Growth factors
  Growth factors (RTK binding)
   111186344 (PDGFB)
Glycosaminoglycan binding proteins [BR:dle00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   111186344 (PDGFB)
SSDB
Motif
Pfam: PDGF PDGF_N
Other DBs
NCBI-GeneID: 111186344
NCBI-ProteinID: XP_022452554
UniProt: A0A2Y9Q0E1
LinkDB
Position
Unknown
AA seq 278 aa
MLARARDPPSPRPPPWPRGRRARSTRPGPRGAGPGVGMNRCWALFLSLCCYLRLVSAEGD
PIPEELYEMLSDHSIRSFDDLQRLLHGDSGDEDGAELDLNLTRSHPGGELDSLSRGRRSL
GSPTVAEPAVIAECKTRTEVFEISRRLIDRTNANFLVWPPCVEVQRCSGCCNNRNVQCRP
TQVQLRPVQVRKIEIVRKKPTFKKATVTLEDHLACKCETVVARPVTRSPGSSQEQRAART
PQTRVTIRTVRVRRPPKGKHRKFKHMHGKKALKETLGA
NT seq 837 nt   +upstreamnt  +downstreamnt
atgctcgctcgggctcgggatccgcccagcccccgccccccaccctggccgcgggggcgg
cgcgctcggtccacgcgtccggggccccgcggggccgggcccggagtcggcatgaatcgc
tgctgggcgctcttcctgtctctctgctgctacctgcgtctggtcagcgccgagggggac
cccattcccgaggagctctacgagatgctgagtgaccactccattcgttccttcgatgac
ctccagcgcctgctgcacggagactccggagatgaagacggggctgaactggacctgaat
ctgacccggtcccatcctggaggcgagctggatagcttatcccgcgggagaaggagcctg
ggttccccaacagtcgctgagccagccgtgatcgccgagtgcaagacacgcaccgaggtg
ttcgagatctcgcggcgcctcatagaccgtaccaacgccaacttcctggtgtggccgccc
tgcgtggaggtgcagcgctgctccggctgctgcaacaaccgcaatgtgcagtgccgcccc
acgcaggtgcagctgcggcccgttcaggtaagaaagattgagattgtacggaagaagcca
acctttaagaaggccacggtgaccttggaggaccacctggcgtgcaagtgtgagacggtg
gtggcacgacccgtgacccgaagtcccgggagttcccaggagcagcgagcagccaggacg
ccccaaactcgggtgaccattcggacggtgcgagtccgccggccccccaaggggaagcac
cggaagttcaagcacatgcatggcaagaaggcactgaaggagaccctcggagcctag

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