KEGG   Delphinapterus leucas (beluga whale): 111171726
Entry
111171726         CDS       T05885                                 

Gene name
CASP8
Definition
(RefSeq) caspase-8
  KO
K04398  caspase 8 [EC:3.4.22.61]
Organism
dle  Delphinapterus leucas (beluga whale)
Pathway
dle01524  Platinum drug resistance
dle04115  p53 signaling pathway
dle04210  Apoptosis
dle04215  Apoptosis - multiple species
dle04217  Necroptosis
dle04620  Toll-like receptor signaling pathway
dle04621  NOD-like receptor signaling pathway
dle04622  RIG-I-like receptor signaling pathway
dle04625  C-type lectin receptor signaling pathway
dle04657  IL-17 signaling pathway
dle04668  TNF signaling pathway
dle04932  Non-alcoholic fatty liver disease
dle05010  Alzheimer disease
dle05016  Huntington disease
dle05022  Pathways of neurodegeneration - multiple diseases
dle05132  Salmonella infection
dle05134  Legionellosis
dle05142  Chagas disease
dle05145  Toxoplasmosis
dle05152  Tuberculosis
dle05160  Hepatitis C
dle05161  Hepatitis B
dle05162  Measles
dle05163  Human cytomegalovirus infection
dle05164  Influenza A
dle05165  Human papillomavirus infection
dle05167  Kaposi sarcoma-associated herpesvirus infection
dle05168  Herpes simplex virus 1 infection
dle05169  Epstein-Barr virus infection
dle05170  Human immunodeficiency virus 1 infection
dle05200  Pathways in cancer
dle05203  Viral carcinogenesis
dle05416  Viral myocarditis
Brite
KEGG Orthology (KO) [BR:dle00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04668 TNF signaling pathway
    111171726 (CASP8)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    111171726 (CASP8)
   04215 Apoptosis - multiple species
    111171726 (CASP8)
   04217 Necroptosis
    111171726 (CASP8)
   04115 p53 signaling pathway
    111171726 (CASP8)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    111171726 (CASP8)
   04621 NOD-like receptor signaling pathway
    111171726 (CASP8)
   04622 RIG-I-like receptor signaling pathway
    111171726 (CASP8)
   04625 C-type lectin receptor signaling pathway
    111171726 (CASP8)
   04657 IL-17 signaling pathway
    111171726 (CASP8)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    111171726 (CASP8)
   05203 Viral carcinogenesis
    111171726 (CASP8)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    111171726 (CASP8)
   05016 Huntington disease
    111171726 (CASP8)
   05022 Pathways of neurodegeneration - multiple diseases
    111171726 (CASP8)
  09166 Cardiovascular disease
   05416 Viral myocarditis
    111171726 (CASP8)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    111171726 (CASP8)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    111171726 (CASP8)
   05134 Legionellosis
    111171726 (CASP8)
   05152 Tuberculosis
    111171726 (CASP8)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    111171726 (CASP8)
   05161 Hepatitis B
    111171726 (CASP8)
   05160 Hepatitis C
    111171726 (CASP8)
   05164 Influenza A
    111171726 (CASP8)
   05162 Measles
    111171726 (CASP8)
   05168 Herpes simplex virus 1 infection
    111171726 (CASP8)
   05163 Human cytomegalovirus infection
    111171726 (CASP8)
   05167 Kaposi sarcoma-associated herpesvirus infection
    111171726 (CASP8)
   05169 Epstein-Barr virus infection
    111171726 (CASP8)
   05165 Human papillomavirus infection
    111171726 (CASP8)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    111171726 (CASP8)
   05142 Chagas disease
    111171726 (CASP8)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    111171726 (CASP8)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:dle01002]
    111171726 (CASP8)
Enzymes [BR:dle01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases
    3.4.22.61  caspase-8
     111171726 (CASP8)
Peptidases and inhibitors [BR:dle01002]
 Cysteine peptidases
  Family C14: caspase family
   111171726 (CASP8)
SSDB
Motif
Pfam: Peptidase_C14 DED Dynamin_N
Other DBs
NCBI-GeneID: 111171726
NCBI-ProteinID: XP_022423110
UniProt: A0A2Y9MQ94
LinkDB
Position
Unknown
AA seq 486 aa
MNFNRCLYNIGEQLNSEDLAALKFLSLDYIPHRKQEPIKDALVLFQRLQEKRMLEESNLS
FLKELLFRMNRLDLLLTYLDTSGEEMERELQMPGRAQISAYRVMLFQISEDVTKLELKDF
KFFLSQEIAKYKLDDDMTLLDIFIEMEKRVILGERNLDTLKRICEQINKSLLKKINDYEE
LSREQRMSLGRGPDEFSNDVSQFLIRGGSLEMLAMSDSPGEKDSESQTSNTVYRMKSKPR
GYCLIFNNYDFSIARKDVPKLHSIKDRNGTDLDAEALRKTFSELHFEIVHYKDYTAKKIC
EVLKSYQSMDHNNKDCFICCILSHGDKGIIYGSDGQEAPIYELTSYFTGSKCPSLLGKPK
IFFIQACQGDNYQRGIAVETDSEQKETYLEIDSSLQKRYIPDEADFLLGMATVNNCVSYR
STMEGTWYIQSLCQSLRERCPRGEDILTILTKVNFEVSNKDDKKNMGKQMPQPTFTLRKK
LFFPLN
NT seq 1461 nt   +upstreamnt  +downstreamnt
atgaatttcaacagatgtctgtataatattggggaacagctgaacagtgaagacctggct
gccctcaagttcctgagcctggactacattccacataggaagcaggaacccatcaaggat
gccttggtgctattccagaggctccaagaaaagagaatgttggaggaaagcaacctgtcc
ttcttgaaggagctgcttttccgaatgaatagactggatctgctgctcacctacctggac
accagtggggaggagatggagagggagcttcagatgccgggcagggcccagatctctgcc
tatagggtcatgctttttcagatttcagaagatgtgaccaaactggaattgaaggacttc
aagttttttttgagccaggagatcgccaaatataagctggatgatgacatgaccttgctt
gatattttcatagagatggagaagagggtcatcctaggggaaagaaacttggacaccctg
aaaagaatctgtgagcaaatcaacaagagcttgctgaagaaaatcaacgattatgaagaa
ctaagcagagagcaaagaatgagccttggaagaggtccagatgaattttcaaacgatgtg
tcacaatttctcataagggggggctcccttgaaatgctggccatgtcggactctccagga
gaaaaggacagtgagtcacagacatcgaacacagtttaccgaatgaaaagcaaacctcgg
ggatactgtttgatctttaacaattatgattttagcatagcaaggaaggatgtgcccaaa
cttcacagcattaaggataggaatggaacagacttggatgcagaggctttgagaaagacc
tttagtgagcttcattttgagatagtgcattacaaagactacactgcgaagaaaatctgt
gaggttctgaaatcctaccaaagcatggaccacaataacaaggactgcttcatctgctgc
atcctctcccatggagacaaaggcatcatctatggctccgatgggcaggaagcccccatc
tatgagctgacctcttacttcactggttcaaagtgcccttcccttcttggcaaacccaaa
atcttttttattcaggcttgtcaaggggataactaccagagaggtatagctgttgaaact
gactcagaacagaaggaaacctatttagaaattgattcatcgcttcagaagagatatatc
ccagatgaggctgactttctgctggggatggccaccgtgaacaactgtgtttcctaccga
agcaccatggaggggacctggtatatccagtcactttgccagagcctgagagaaagatgt
cctaggggtgaagatattctcaccatcctcaccaaggtgaactttgaagtaagcaataag
gatgacaagaaaaatatgggcaaacagatgccacaacctactttcacactgaggaaaaaa
ctcttctttccccttaattga

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