Delphinapterus leucas (beluga whale): 111171726 Help Entry 111171726         CDS       T05885                                  Gene name CASP8 Definition (RefSeq) caspase-8   KO K04398   caspase 8 [EC:3.4.22.61] Organism dle  Delphinapterus leucas (beluga whale) Pathway dle01524   Platinum drug resistance dle04115   p53 signaling pathway dle04210   Apoptosis dle04215   Apoptosis - multiple species dle04217   Necroptosis dle04620   Toll-like receptor signaling pathway dle04621   NOD-like receptor signaling pathway dle04622   RIG-I-like receptor signaling pathway dle04625   C-type lectin receptor signaling pathway dle04657   IL-17 signaling pathway dle04668   TNF signaling pathway dle04932   Non-alcoholic fatty liver disease dle05010   Alzheimer disease dle05016   Huntington disease dle05022   Pathways of neurodegeneration - multiple diseases dle05132   Salmonella infection dle05134   Legionellosis dle05142   Chagas disease dle05145   Toxoplasmosis dle05152   Tuberculosis dle05160   Hepatitis C dle05161   Hepatitis B dle05162   Measles dle05163   Human cytomegalovirus infection dle05164   Influenza A dle05165   Human papillomavirus infection dle05167   Kaposi sarcoma-associated herpesvirus infection dle05168   Herpes simplex virus 1 infection dle05169   Epstein-Barr virus infection dle05170   Human immunodeficiency virus 1 infection dle05200   Pathways in cancer dle05203   Viral carcinogenesis dle05416   Viral myocarditis Brite KEGG Orthology (KO) [BR:dle00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     111171726 (CASP8)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     111171726 (CASP8)    04215 Apoptosis - multiple species     111171726 (CASP8)    04217 Necroptosis     111171726 (CASP8)    04115 p53 signaling pathway     111171726 (CASP8)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     111171726 (CASP8)    04621 NOD-like receptor signaling pathway     111171726 (CASP8)    04622 RIG-I-like receptor signaling pathway     111171726 (CASP8)    04625 C-type lectin receptor signaling pathway     111171726 (CASP8)    04657 IL-17 signaling pathway     111171726 (CASP8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     111171726 (CASP8)    05203 Viral carcinogenesis     111171726 (CASP8)   09164 Neurodegenerative disease    05010 Alzheimer disease     111171726 (CASP8)    05016 Huntington disease     111171726 (CASP8)    05022 Pathways of neurodegeneration - multiple diseases     111171726 (CASP8)   09166 Cardiovascular disease    05416 Viral myocarditis     111171726 (CASP8)   09167 Endocrine and metabolic disease    04932 Non-alcoholic fatty liver disease     111171726 (CASP8)   09171 Infectious disease: bacterial    05132 Salmonella infection     111171726 (CASP8)    05134 Legionellosis     111171726 (CASP8)    05152 Tuberculosis     111171726 (CASP8)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     111171726 (CASP8)    05161 Hepatitis B     111171726 (CASP8)    05160 Hepatitis C     111171726 (CASP8)    05164 Influenza A     111171726 (CASP8)    05162 Measles     111171726 (CASP8)    05168 Herpes simplex virus 1 infection     111171726 (CASP8)    05163 Human cytomegalovirus infection     111171726 (CASP8)    05167 Kaposi sarcoma-associated herpesvirus infection     111171726 (CASP8)    05169 Epstein-Barr virus infection     111171726 (CASP8)    05165 Human papillomavirus infection     111171726 (CASP8)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     111171726 (CASP8)    05142 Chagas disease     111171726 (CASP8)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     111171726 (CASP8)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:dle01002]     111171726 (CASP8) Enzymes [BR:dle01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      111171726 (CASP8) Peptidases and inhibitors [BR:dle01002]  Cysteine peptidases   Family C14: caspase family    111171726 (CASP8) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Peptidase_C14 DED Dynamin_N Motif Other DBs NCBI-GeneID:  111171726 NCBI-ProteinID:  XP_022423110 UniProt:  A0A2Y9MQ94 LinkDB All DBs Position Unknown AA seq 486 aa AA seqDB search MNFNRCLYNIGEQLNSEDLAALKFLSLDYIPHRKQEPIKDALVLFQRLQEKRMLEESNLS FLKELLFRMNRLDLLLTYLDTSGEEMERELQMPGRAQISAYRVMLFQISEDVTKLELKDF KFFLSQEIAKYKLDDDMTLLDIFIEMEKRVILGERNLDTLKRICEQINKSLLKKINDYEE LSREQRMSLGRGPDEFSNDVSQFLIRGGSLEMLAMSDSPGEKDSESQTSNTVYRMKSKPR GYCLIFNNYDFSIARKDVPKLHSIKDRNGTDLDAEALRKTFSELHFEIVHYKDYTAKKIC EVLKSYQSMDHNNKDCFICCILSHGDKGIIYGSDGQEAPIYELTSYFTGSKCPSLLGKPK IFFIQACQGDNYQRGIAVETDSEQKETYLEIDSSLQKRYIPDEADFLLGMATVNNCVSYR STMEGTWYIQSLCQSLRERCPRGEDILTILTKVNFEVSNKDDKKNMGKQMPQPTFTLRKK LFFPLN NT seq 1461 nt NT seq  +upstreamnt  +downstreamnt atgaatttcaacagatgtctgtataatattggggaacagctgaacagtgaagacctggct gccctcaagttcctgagcctggactacattccacataggaagcaggaacccatcaaggat gccttggtgctattccagaggctccaagaaaagagaatgttggaggaaagcaacctgtcc ttcttgaaggagctgcttttccgaatgaatagactggatctgctgctcacctacctggac accagtggggaggagatggagagggagcttcagatgccgggcagggcccagatctctgcc tatagggtcatgctttttcagatttcagaagatgtgaccaaactggaattgaaggacttc aagttttttttgagccaggagatcgccaaatataagctggatgatgacatgaccttgctt gatattttcatagagatggagaagagggtcatcctaggggaaagaaacttggacaccctg aaaagaatctgtgagcaaatcaacaagagcttgctgaagaaaatcaacgattatgaagaa ctaagcagagagcaaagaatgagccttggaagaggtccagatgaattttcaaacgatgtg tcacaatttctcataagggggggctcccttgaaatgctggccatgtcggactctccagga gaaaaggacagtgagtcacagacatcgaacacagtttaccgaatgaaaagcaaacctcgg ggatactgtttgatctttaacaattatgattttagcatagcaaggaaggatgtgcccaaa cttcacagcattaaggataggaatggaacagacttggatgcagaggctttgagaaagacc tttagtgagcttcattttgagatagtgcattacaaagactacactgcgaagaaaatctgt gaggttctgaaatcctaccaaagcatggaccacaataacaaggactgcttcatctgctgc atcctctcccatggagacaaaggcatcatctatggctccgatgggcaggaagcccccatc tatgagctgacctcttacttcactggttcaaagtgcccttcccttcttggcaaacccaaa atcttttttattcaggcttgtcaaggggataactaccagagaggtatagctgttgaaact gactcagaacagaaggaaacctatttagaaattgattcatcgcttcagaagagatatatc ccagatgaggctgactttctgctggggatggccaccgtgaacaactgtgtttcctaccga agcaccatggaggggacctggtatatccagtcactttgccagagcctgagagaaagatgt cctaggggtgaagatattctcaccatcctcaccaaggtgaactttgaagtaagcaataag gatgacaagaaaaatatgggcaaacagatgccacaacctactttcacactgaggaaaaaa ctcttctttccccttaattga

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