KEGG   Delphinapterus leucas (beluga whale): 111173795
Entry
111173795         CDS       T05885                                 

Gene name
TBK1
Definition
(RefSeq) serine/threonine-protein kinase TBK1
  KO
K05410  TANK-binding kinase 1 [EC:2.7.11.10]
Organism
dle  Delphinapterus leucas (beluga whale)
Pathway
dle04014  Ras signaling pathway
dle04137  Mitophagy - animal
dle04140  Autophagy - animal
dle04620  Toll-like receptor signaling pathway
dle04621  NOD-like receptor signaling pathway
dle04622  RIG-I-like receptor signaling pathway
dle04623  Cytosolic DNA-sensing pathway
dle04657  IL-17 signaling pathway
dle05014  Amyotrophic lateral sclerosis
dle05022  Pathways of neurodegeneration - multiple diseases
dle05135  Yersinia infection
dle05160  Hepatitis C
dle05161  Hepatitis B
dle05162  Measles
dle05163  Human cytomegalovirus infection
dle05164  Influenza A
dle05165  Human papillomavirus infection
dle05167  Kaposi sarcoma-associated herpesvirus infection
dle05168  Herpes simplex virus 1 infection
dle05169  Epstein-Barr virus infection
dle05170  Human immunodeficiency virus 1 infection
dle05171  Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:dle00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    111173795 (TBK1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    111173795 (TBK1)
   04137 Mitophagy - animal
    111173795 (TBK1)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    111173795 (TBK1)
   04621 NOD-like receptor signaling pathway
    111173795 (TBK1)
   04622 RIG-I-like receptor signaling pathway
    111173795 (TBK1)
   04623 Cytosolic DNA-sensing pathway
    111173795 (TBK1)
   04657 IL-17 signaling pathway
    111173795 (TBK1)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    111173795 (TBK1)
   05022 Pathways of neurodegeneration - multiple diseases
    111173795 (TBK1)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    111173795 (TBK1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    111173795 (TBK1)
   05161 Hepatitis B
    111173795 (TBK1)
   05160 Hepatitis C
    111173795 (TBK1)
   05171 Coronavirus disease - COVID-19
    111173795 (TBK1)
   05164 Influenza A
    111173795 (TBK1)
   05162 Measles
    111173795 (TBK1)
   05168 Herpes simplex virus 1 infection
    111173795 (TBK1)
   05163 Human cytomegalovirus infection
    111173795 (TBK1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    111173795 (TBK1)
   05169 Epstein-Barr virus infection
    111173795 (TBK1)
   05165 Human papillomavirus infection
    111173795 (TBK1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:dle01001]
    111173795 (TBK1)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:dle04131]
    111173795 (TBK1)
Enzymes [BR:dle01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.10  IkappaB kinase
     111173795 (TBK1)
Protein kinases [BR:dle01001]
 Serine/threonine kinases: Other
  IKK family [OT]
   111173795 (TBK1)
Membrane trafficking [BR:dle04131]
 Autophagy
  Xenophagy
   Other xenophagy associated proteins
    111173795 (TBK1)
SSDB
Motif
Pfam: TBK1_CCD1 Pkinase TBK1_ULD PK_Tyr_Ser-Thr Pkinase_fungal Kinase-like DUF713 CEP63 ubiquitin
Other DBs
NCBI-GeneID: 111173795
NCBI-ProteinID: XP_022427338
UniProt: A0A2Y9NDL9
LinkDB
Position
Unknown
AA seq 729 aa
MQSTSNHLWLLSDILGQGATANVFRGRHKKTGDLFAIKVFNNISFLRPVDVQMREFEVLK
KLNHKNIVKLFAIEEEITTRHKVLIMEFCPCGSLYTVLEEPCNAYGLPESEFLIVLRDVV
GGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDEQFVSLYGTEEYL
HPDMYERAVLRKDHQKKYGATVDLWSIGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITG
KPSGAISGVQKAENGPIDWSGDMPVSCSLSRGLQVLLTPVLANILEADQEKCWGFDQFFA
ETSDILHRMIIHVFSLQQMTAHKIYIHSYNTATVFHELVYKQTKIISSNQELIYEGRRLV
LEPGRLAQHFPKTADENPIFVVSREPLSTIGLIYEKISLPKVHPRYDLDGDASMAKAVTG
VVCYACRIASTLLLYQELMRKGIRWLIELVKDDYNETVHKKTEVVITLDFCIRNIEKTVK
VYEKLMKINLEAAELGEISDIHTKLLRLSSSQGTIETSLQDIESKLSPGGLLADTWTHQE
GTHPKDRHVEKLQVLLNCITEIYYQFKKDKAERRLAYNEEQIHKFDKQKLYYHATKAMTH
FTDECVKKYEAFLDKSEEWMRKMLHLRKQLLSLTNQCFDIEEEVSKYQDYTNELQETLPQ
KMFAASSGIKHTMTPIYPCSNTLVEMTLGMKKLKEEMEGVVKELAENNHILERFGSLTMD
GGLRNVDCL
NT seq 2190 nt   +upstreamnt  +downstreamnt
atgcagagcacttctaatcatctgtggcttttatctgatattttaggccaaggagctact
gcaaatgtctttcgtggaagacataagaaaactggtgacttatttgctatcaaagtattt
aataacataagctttcttcgtccagtggatgttcaaatgagagaatttgaagtgttaaaa
aaactcaaccacaaaaatattgtcaaattatttgctattgaagaggagataacaacgaga
cataaagtacttattatggaattttgtccatgtggaagtttatacactgttttagaagaa
ccatgtaatgcctatggactaccagagtctgaatttttaattgttttgcgagatgtggtg
ggtggaatgaatcatctccgagaaaatggcatagttcaccgtgatattaagccaggaaat
atcatgcgtgtaataggggaagacggacagtctgtgtacaaactcacagattttggtgca
gctagagaattagaagatgatgagcagtttgtttctctgtatggcacagaagaatatttg
catcctgatatgtatgagagagcagtgctgagaaaagatcatcagaagaaatatggagcg
actgttgatctttggagcattggggtaacattttaccatgcagctactggatcactgcca
tttagaccatttgaagggccgcgtaggaataaggaagtgatgtataaaataattactgga
aagccttctggtgcaatatctggagtacagaaagcagaaaatggaccaattgactggagt
ggagacatgcctgtttcttgtagtctttctcggggtcttcaagttctacttacccctgtt
cttgcaaacatccttgaggcagatcaggaaaagtgttggggttttgaccagttttttgca
gaaacaagtgatatacttcaccggatgataattcatgttttttcgctacaacaaatgaca
gctcataaaatttatattcatagctataatactgctactgtatttcatgaactggtgtat
aaacagaccaaaattatttcttcaaatcaagaacttatatatgaaggacgacgtttagtt
ctagaacctggaagactggcacaacatttccctaaaactgctgatgaaaatcccatcttt
gtagtaagccgggaacctctgagtacaataggattgatatatgaaaaaatttccctccct
aaagtacatccacgttatgatttagatggggatgccagcatggctaaggcagtaacagga
gttgtgtgttatgcctgtagaattgccagtaccttgctgctttatcaggaattaatgcga
aaggggatacgatggttgatagaattagttaaagatgattataatgaaactgttcacaaa
aagacggaagttgtgatcacattagatttctgcatcagaaacattgaaaagactgtgaaa
gtatatgaaaagttgatgaagatcaacctagaagcagcagagttaggtgaaatttcagac
atacacaccaaactgttgagactttccagttctcagggaacaatagaaaccagtcttcag
gatattgaaagcaaattatctccaggtggattgctggcagatacatggacccatcaagaa
ggcactcatccaaaagatagacatgtagaaaagctacaagtcctgttaaactgcatcaca
gagatttactatcagttcaaaaaagacaaagcagaacgtagactagcttataatgaagaa
caaatccacaaatttgataagcaaaaactgtattatcatgcaacaaaagctatgacccac
tttacagatgaatgtgttaaaaagtatgaggcttttttggataagtcagaagaatggatg
agaaagatgcttcatcttaggaaacagttattatccctaactaatcagtgttttgatatt
gaagaagaagtatcaaagtatcaagactatactaatgagttacaagaaactttgccacag
aaaatgtttgcagcctccagtggaatcaaacataccatgaccccaatttatccatgttct
aacacattagtagaaatgactcttggtatgaagaaattaaaggaagaaatggaaggggta
gttaaagaacttgctgaaaataatcatattttagaaaggtttggctctttaactatggat
ggtggccttcgcaatgttgactgtctatag

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