Delphinapterus leucas (beluga whale): 111176049 Help Entry 111176049         CDS       T05885                                  Gene name TRAF3 Definition (RefSeq) TNF receptor-associated factor 3 isoform X1   KO K03174   TNF receptor-associated factor 3 Organism dle  Delphinapterus leucas (beluga whale) Pathway dle04064   NF-kappa B signaling pathway dle04620   Toll-like receptor signaling pathway dle04621   NOD-like receptor signaling pathway dle04622   RIG-I-like receptor signaling pathway dle04657   IL-17 signaling pathway dle04668   TNF signaling pathway dle05160   Hepatitis C dle05161   Hepatitis B dle05162   Measles dle05164   Influenza A dle05165   Human papillomavirus infection dle05167   Kaposi sarcoma-associated herpesvirus infection dle05168   Herpes simplex virus 1 infection dle05169   Epstein-Barr virus infection dle05171   Coronavirus disease - COVID-19 dle05200   Pathways in cancer dle05203   Viral carcinogenesis dle05222   Small cell lung cancer Brite KEGG Orthology (KO) [BR:dle00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     111176049 (TRAF3)    04668 TNF signaling pathway     111176049 (TRAF3)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     111176049 (TRAF3)    04621 NOD-like receptor signaling pathway     111176049 (TRAF3)    04622 RIG-I-like receptor signaling pathway     111176049 (TRAF3)    04657 IL-17 signaling pathway     111176049 (TRAF3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     111176049 (TRAF3)    05203 Viral carcinogenesis     111176049 (TRAF3)   09162 Cancer: specific types    05222 Small cell lung cancer     111176049 (TRAF3)   09172 Infectious disease: viral    05161 Hepatitis B     111176049 (TRAF3)    05160 Hepatitis C     111176049 (TRAF3)    05171 Coronavirus disease - COVID-19     111176049 (TRAF3)    05164 Influenza A     111176049 (TRAF3)    05162 Measles     111176049 (TRAF3)    05168 Herpes simplex virus 1 infection     111176049 (TRAF3)    05167 Kaposi sarcoma-associated herpesvirus infection     111176049 (TRAF3)    05169 Epstein-Barr virus infection     111176049 (TRAF3)    05165 Human papillomavirus infection     111176049 (TRAF3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  zf-TRAF zf-C3HC4 ATG16 Spc7 MPS2 Spc29 zf-C3HC4_2 zf-RING_4 Cast Tropomyosin_1 Sina zf-RING_5 KxDL Crescentin GAS Fib_alpha ADIP LMBR1 FliJ DUF3450 DUF1664 SPATA24 Motif Other DBs NCBI-GeneID:  111176049 NCBI-ProteinID:  XP_022431739 UniProt:  A0A2Y9NC44 LinkDB All DBs Position Unknown AA seq 572 aa AA seqDB search MTHRMEPSKKLDAAGTLPANPPLKLHPDRGAGPAVLVPEQGGYKERFVKAVEDKYKCEKC RLVLCNPKQTECGHRFCETCMGALLSSSSPKCTACREGISKDKVFKDNCCKREILALQIY CRNEGRGCAEQLALGHLLVHLKNDCQFEELLCVRADCKEKVLRKDLRDHVDKACKYREAT CGHCRSQVPMITLQKHEDTECPCVVVSCPHKCSVQTLLRSELSAHLSECVNAPSTCSFKR YGCVFQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQIC SFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQSWEEAGSMKSSVES LQSRVTELESVDKSAGQAARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNG VLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFV IMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPV FVAQTVLENGTYIKDDTIFIKVIVDTSDLPDP NT seq 1719 nt NT seq  +upstreamnt  +downstreamnt atgacacacaggatggagccgagtaaaaagctggacgcagccggcaccctgccagccaac cccccactgaagctgcaccccgaccgcggcgccgggcctgccgtcctggtccccgagcag gggggctacaaggagcgcttcgtgaaggccgtggaggacaagtacaagtgtgagaagtgc cgcctggtgctctgcaaccccaagcagaccgagtgcggacaccgcttctgcgagacctgc atgggcgccctgctcagctcctccagcccgaaatgcactgcgtgtcgagaaggcatcagc aaagacaaggtgtttaaggataattgctgcaagagagagattctggcccttcagatatac tgtaggaacgaaggcagaggctgtgcagagcagttagcactggggcacctgctggtgcat ttgaagaatgattgccagtttgaggaacttttgtgtgtccgtgccgactgcaaagagaag gtgctgaggaaggacctgcgtgaccacgtggacaaggcctgtaaataccgtgaggccacg tgcggccactgcagaagccaggtcccgatgataacgctgcagaaacacgaagacaccgag tgtccctgcgtggtggtgtcctgccctcataagtgcagtgtccagacccttctgaggagc gagttgagtgcacacttgtcagagtgtgtcaatgcccccagcacctgtagttttaagcgc tatggctgcgtttttcaggggacaaaccagcagattaaggcccacgaggccagctccgcg gtgcagcatgtcaacttactcaaagaatggagcaactctctagagaaaaaggtttccttg ctgcagaatgaaagcgtagaaaaaaacaagagcatacagagtttgcacaaccagatatgc agctttgaaattgaaattgagagacaaaaggaaatgcttcgaaataatgaatccaaaata cttcatttacagcgagtaatagacagccaagcagagaaactgaaggagctcgacaaggag atccgccccttccggcagagctgggaggaggcaggcagcatgaagagcagcgtggagtcg ctccagagccgggtgaccgagctggagagtgtggacaagagtgcggggcaggcggctcgg aacacaggcctgctggagtcccagctgagccggcacgaccagatgctgagtgtccacgac atccgcctggccgacatggacctgcggttccaggtcctggagaccgccagctacaacggt gtgctgatctggaagatccgggattacaagcggcggaagcaggaggccgtcatggggaag accctgtccctctacagccagcctttctacaccggctatttcggctacaagatgtgcgcc agggtctacctgaacggggatggcatgggcaaggggacgcacctgtcgctgttcttcgtc atcatgcgcggagaatacgacgccctccttccctggccgttcaagcagaaggtgacgctc atgctgatggaccaggggtcctcccggcgacacttgggggacgctttcaagccggacccc aacagcagcagcttcaagaagcccaccggcgagatgaacatcgcttccggctgcccagtc ttcgtggcgcagactgtgctggaaaacgggacgtacattaaagatgataccatttttatc aaagtcatagtggatacttcggacctgccagacccctga

Delphinapterus leucas (beluga whale): 111177009 Help Entry 111177009         CDS       T05885                                  Gene name TRAF2 Definition (RefSeq) TNF receptor-associated factor 2   KO K03173   TNF receptor-associated factor 2 [EC:2.3.2.27] Organism dle  Delphinapterus leucas (beluga whale) Pathway dle04010   MAPK signaling pathway dle04064   NF-kappa B signaling pathway dle04071   Sphingolipid signaling pathway dle04141   Protein processing in endoplasmic reticulum dle04210   Apoptosis dle04217   Necroptosis dle04380   Osteoclast differentiation dle04621   NOD-like receptor signaling pathway dle04622   RIG-I-like receptor signaling pathway dle04657   IL-17 signaling pathway dle04668   TNF signaling pathway dle04920   Adipocytokine signaling pathway dle04932   Non-alcoholic fatty liver disease dle05010   Alzheimer disease dle05014   Amyotrophic lateral sclerosis dle05016   Huntington disease dle05017   Spinocerebellar ataxia dle05022   Pathways of neurodegeneration - multiple diseases dle05132   Salmonella infection dle05135   Yersinia infection dle05160   Hepatitis C dle05163   Human cytomegalovirus infection dle05167   Kaposi sarcoma-associated herpesvirus infection dle05168   Herpes simplex virus 1 infection dle05169   Epstein-Barr virus infection dle05170   Human immunodeficiency virus 1 infection dle05200   Pathways in cancer dle05203   Viral carcinogenesis dle05222   Small cell lung cancer Brite KEGG Orthology (KO) [BR:dle00001]  09120 Genetic Information Processing   09123 Folding, sorting and degradation    04141 Protein processing in endoplasmic reticulum     111177009 (TRAF2)  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     111177009 (TRAF2)    04064 NF-kappa B signaling pathway     111177009 (TRAF2)    04668 TNF signaling pathway     111177009 (TRAF2)    04071 Sphingolipid signaling pathway     111177009 (TRAF2)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     111177009 (TRAF2)    04217 Necroptosis     111177009 (TRAF2)  09150 Organismal Systems   09151 Immune system    04621 NOD-like receptor signaling pathway     111177009 (TRAF2)    04622 RIG-I-like receptor signaling pathway     111177009 (TRAF2)    04657 IL-17 signaling pathway     111177009 (TRAF2)   09152 Endocrine system    04920 Adipocytokine signaling pathway     111177009 (TRAF2)   09158 Development and regeneration    04380 Osteoclast differentiation     111177009 (TRAF2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     111177009 (TRAF2)    05203 Viral carcinogenesis     111177009 (TRAF2)   09162 Cancer: specific types    05222 Small cell lung cancer     111177009 (TRAF2)   09164 Neurodegenerative disease    05010 Alzheimer disease     111177009 (TRAF2)    05014 Amyotrophic lateral sclerosis     111177009 (TRAF2)    05016 Huntington disease     111177009 (TRAF2)    05017 Spinocerebellar ataxia     111177009 (TRAF2)    05022 Pathways of neurodegeneration - multiple diseases     111177009 (TRAF2)   09167 Endocrine and metabolic disease    04932 Non-alcoholic fatty liver disease     111177009 (TRAF2)   09171 Infectious disease: bacterial    05132 Salmonella infection     111177009 (TRAF2)    05135 Yersinia infection     111177009 (TRAF2)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     111177009 (TRAF2)    05160 Hepatitis C     111177009 (TRAF2)    05168 Herpes simplex virus 1 infection     111177009 (TRAF2)    05163 Human cytomegalovirus infection     111177009 (TRAF2)    05167 Kaposi sarcoma-associated herpesvirus infection     111177009 (TRAF2)    05169 Epstein-Barr virus infection     111177009 (TRAF2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03019 Messenger RNA biogenesis [BR:dle03019]     111177009 (TRAF2)    04121 Ubiquitin system [BR:dle04121]     111177009 (TRAF2) Enzymes [BR:dle01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      111177009 (TRAF2) Messenger RNA biogenesis [BR:dle03019]  Eukaryotic type   mRNA surveillance and transport factors    mRNA cycle factors     Stress granule specific factors      111177009 (TRAF2) Ubiquitin system [BR:dle04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    TRAF proteins     111177009 (TRAF2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  TRAF_BIRC3_bd zf-TRAF zf-C3HC4 zf-RING_6 zf-C3HC4_2 zf-C3HC4_4 Motif Other DBs NCBI-GeneID:  111177009 NCBI-ProteinID:  XP_022433841 UniProt:  A0A2Y9NLV0 LinkDB All DBs Position Unknown AA seq 516 aa AA seqDB search MAAASATPPGSLDLLQPGFSKTLLGTKLEDKYLCSACRNVLRRPFQAQCGHRYCSFCLSS ILSSGPQNCAACVNEGIYEEGVSILESSSAFPDNAARREVESLPAVCSSEGCTWKGTLKE YESGHEGHCPFVLTECPACKGLVRLGEKEHHLEHACPERSLSCRHCRVPCCSADMKAHHQ VCPKFPLTCEGCGKKKITREKFQDHVRTCGRCRVPCRFHAVGCPEMVEGEKLQEHEAQRL REHLALLLGALLEAGPPLLSQGEQGWGASTPGPAAAPSQAAELLQRCEALERKTATFENI VCVLNREVERVAVTAEACGRQHRLDQDRIEALSNKVQQLERSIGLKDLAMADLEQKVHEM EASTFDGVFIWKIPDFARKRQEAVSGRTPAIFSPAFYTSRYGYKMCLRAYLNGDGTGRGT HLSLFFVLMKGPHDALLHWPFNQKVTLMLLDQNNREHVIDAFRPDVTSSSFQRPVSDMNI ASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVDLTGL NT seq 1551 nt NT seq  +upstreamnt  +downstreamnt atggctgcagccagcgcgacccctcccggctccctggacctgctgcagcctggcttctcc aagaccctcctggggaccaagctagaggacaagtacctgtgctcggcctgcaggaacgtc ctgcgcaggcccttccaggctcagtgtggccaccgctattgttccttctgcctgagcagc atcctgagctccgggccccagaactgtgccgcctgcgtgaacgagggcatttacgaggaa ggcgtctctatcctggagagcagctcggctttcccggacaatgctgcccgcagggaggta gagagcctgccggccgtctgttccagcgagggctgcacctggaaggggaccctgaaggag tacgagagtggccacgaaggacactgcccgttcgtgctgaccgagtgcccggcgtgtaaa ggcctggtgcgcctgggcgagaaggaacaccacctggagcacgcgtgcccggagcgaagc ctcagctgccggcactgcagggtgccctgctgctcggccgacatgaaggcgcaccaccag gtctgccccaagttccccttgacctgcgagggctgcggcaagaagaagatcacacgcgag aaatttcaggaccacgtcaggacatgtggcagatgccgagtcccctgcaggttccacgct gtcggctgccccgagatggtggagggcgagaagctgcaggagcacgaggcgcagcggctc cgggagcacctggccctgcttctgggcgccctcctggaggccgggccccccctcctcagc cagggcgagcagggctggggggccagcacgccaggcccggcggcagcgccctcccaggcg gcggagctgctgcagaggtgcgaggccctggagcggaagacggccaccttcgagaacatc gtctgcgtgctgaaccgggaggtggagcgggtggctgtgactgccgaggcctgcggccgg cagcaccggctggaccaagacaggatcgaagccctgagtaataaggtgcagcagctggag aggagcatcggcctgaaggacctggccatggctgacctggagcagaaggtccacgagatg gaggcgtccaccttcgacggggtgttcatctggaagatcccggacttcgccaggaagcgc caggaagccgtgtctggccgcacacccgccatcttctccccagccttctacaccagcaga tacggctacaagatgtgtctgcgcgcctacctgaacggagatggcaccgggcgcgggacg cacctgtccctcttcttcgttctgatgaagggcccccacgacgccctcctgcactggccc ttcaaccagaaggtgaccctgatgttgctggaccagaacaaccgggagcatgtgattgac gccttcaggcccgacgtgacctcatcctcgttccagaggccggtcagcgacatgaacatc gcgagcggctgcccgcttttctgccctgtctccaagatggaggccaagaattcctacgtg cgtgacgacgccatcttcatcaaggccatagtggacctgacagggctctag

Delphinapterus leucas (beluga whale): 111177267 Help Entry 111177267         CDS       T05885                                  Gene name TRAF1 Definition (RefSeq) TNF receptor-associated factor 1   KO K03172   TNF receptor-associated factor 1 Organism dle  Delphinapterus leucas (beluga whale) Pathway dle04064   NF-kappa B signaling pathway dle04210   Apoptosis dle04668   TNF signaling pathway dle05200   Pathways in cancer dle05202   Transcriptional misregulation in cancer dle05203   Viral carcinogenesis dle05222   Small cell lung cancer Brite KEGG Orthology (KO) [BR:dle00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     111177267 (TRAF1)    04668 TNF signaling pathway     111177267 (TRAF1)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     111177267 (TRAF1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     111177267 (TRAF1)    05202 Transcriptional misregulation in cancer     111177267 (TRAF1)    05203 Viral carcinogenesis     111177267 (TRAF1)   09162 Cancer: specific types    05222 Small cell lung cancer     111177267 (TRAF1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  TRAF_BIRC3_bd Motif Other DBs NCBI-GeneID:  111177267 NCBI-ProteinID:  XP_022434586 UniProt:  A0A2Y9NTP2 LinkDB All DBs Position Unknown AA seq 415 aa AA seqDB search MASGSASSRHPAPDENEFPFGCPPTVCQDPPEPRPLCCSVCLSENVRNGEDRICPKCKGD DTPSERPGSLLSQEQDHSEVAEAGVGCPFAGVGCAFKGGPKFMQEHEVTSQATHLNLLLG FMKQWKTQLGSGLGSGPMALERNLSDLQLQGAVEAAGDLEVDCYRAPCSESQEELALQHF MKEKLLTELEGKLCVFENIVAVLNKEVEASHLALAASIHQSRLGREHILSLERRVMELQQ TLAQKDQALVKLEQSFRLMEEASYDGTFLWKVTSVTRRCHESACGRTVSLFSPAFYTAKY GYKLCLRLYLNGDGTGKRTHLSLFIVIMRGEYDALLPWPFRNKVTFMLLDQNNREHAIDA FRPDLNSASFQRPQSETNVASGCPLFFPLNKLQSPKHAYVKDDTMFLKCIVETDA NT seq 1248 nt NT seq  +upstreamnt  +downstreamnt atggcctctggctcggccagcagccgccaccccgcccccgatgagaacgagttccccttt gggtgcccccccaccgtctgccaggacccaccagagcccaggcccctctgctgctccgtc tgtctctctgagaacgtgaggaatggtgaggatcggatctgtcccaaatgcaaaggggac gacacaccatctgagaggccaggaagccttctgtctcaggagcaggatcactccgaggtg gctgaggctggagttgggtgtccctttgcaggtgttggctgcgccttcaaggggggccca aagttcatgcaggagcatgaggtcacctcccaggctacccacctgaacctgctgttaggg ttcatgaaacagtggaagacccagctgggctctggcctggggtctggacccatggccctg gagcggaatctgtcagacctgcagctgcagggggctgtggaggcagctggggacctagag gtggactgctaccgggccccctgctccgagagccaggaggagctggccctgcagcacttc atgaaggagaagctcctgactgagctggaggggaagctgtgcgtgtttgagaacattgtc gccgtcctcaacaaggaggtggaggcctcccacctggccctggccgcctccatccaccag agccggctgggccgtgagcacatcctgagcttggaacggagggtgatggagctgcagcag accttggcccagaaagaccaggccctggtcaagctggagcagagcttccgcctcatggaa gaggcctcctacgacggcacgttcctatggaaggtcaccagtgtcaccaggcggtgccat gagtcagcctgcggcaggaccgtcagcctcttctccccagctttctacactgccaagtac ggatacaagctgtgcctgcggctctacctgaatggggacgggacggggaagaggacccac ctgtccctcttcatcgtgatcatgagaggggagtatgatgctctgttgccgtggcctttc cggaacaaggtcactttcatgctgctcgaccagaacaaccgtgagcacgccatcgacgcc ttccggcccgacctgaactcagcatccttccagcggccccagagcgaaaccaatgtggcc agcggctgcccactcttcttccccctcaacaagctgcagtctcccaagcatgcctacgtg aaggacgacaccatgttcctcaagtgcatcgtggagacagacgcttag

Delphinapterus leucas (beluga whale): 111179772 Help Entry 111179772         CDS       T05885                                  Gene name TRAF6 Definition (RefSeq) TNF receptor-associated factor 6 isoform X1   KO K03175   TNF receptor-associated factor 6 [EC:2.3.2.27] Organism dle  Delphinapterus leucas (beluga whale) Pathway dle04010   MAPK signaling pathway dle04064   NF-kappa B signaling pathway dle04120   Ubiquitin mediated proteolysis dle04140   Autophagy - animal dle04144   Endocytosis dle04380   Osteoclast differentiation dle04620   Toll-like receptor signaling pathway dle04621   NOD-like receptor signaling pathway dle04622   RIG-I-like receptor signaling pathway dle04657   IL-17 signaling pathway dle04722   Neurotrophin signaling pathway dle05132   Salmonella infection dle05133   Pertussis dle05135   Yersinia infection dle05140   Leishmaniasis dle05142   Chagas disease dle05145   Toxoplasmosis dle05152   Tuberculosis dle05160   Hepatitis C dle05161   Hepatitis B dle05162   Measles dle05168   Herpes simplex virus 1 infection dle05169   Epstein-Barr virus infection dle05170   Human immunodeficiency virus 1 infection dle05171   Coronavirus disease - COVID-19 dle05200   Pathways in cancer dle05222   Small cell lung cancer dle05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:dle00001]  09120 Genetic Information Processing   09123 Folding, sorting and degradation    04120 Ubiquitin mediated proteolysis     111179772 (TRAF6)  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     111179772 (TRAF6)    04064 NF-kappa B signaling pathway     111179772 (TRAF6)  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     111179772 (TRAF6)    04140 Autophagy - animal     111179772 (TRAF6)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     111179772 (TRAF6)    04621 NOD-like receptor signaling pathway     111179772 (TRAF6)    04622 RIG-I-like receptor signaling pathway     111179772 (TRAF6)    04657 IL-17 signaling pathway     111179772 (TRAF6)   09156 Nervous system    04722 Neurotrophin signaling pathway     111179772 (TRAF6)   09158 Development and regeneration    04380 Osteoclast differentiation     111179772 (TRAF6)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     111179772 (TRAF6)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     111179772 (TRAF6)   09162 Cancer: specific types    05222 Small cell lung cancer     111179772 (TRAF6)   09171 Infectious disease: bacterial    05132 Salmonella infection     111179772 (TRAF6)    05135 Yersinia infection     111179772 (TRAF6)    05133 Pertussis     111179772 (TRAF6)    05152 Tuberculosis     111179772 (TRAF6)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     111179772 (TRAF6)    05161 Hepatitis B     111179772 (TRAF6)    05160 Hepatitis C     111179772 (TRAF6)    05171 Coronavirus disease - COVID-19     111179772 (TRAF6)    05162 Measles     111179772 (TRAF6)    05168 Herpes simplex virus 1 infection     111179772 (TRAF6)    05169 Epstein-Barr virus infection     111179772 (TRAF6)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     111179772 (TRAF6)    05140 Leishmaniasis     111179772 (TRAF6)    05142 Chagas disease     111179772 (TRAF6)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:dle04131]     111179772 (TRAF6)    04121 Ubiquitin system [BR:dle04121]     111179772 (TRAF6) Enzymes [BR:dle01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      111179772 (TRAF6) Membrane trafficking [BR:dle04131]  Endocytosis   Clathrin-mediated endocytosis    Ubiquitin E3 ligases     111179772 (TRAF6) Ubiquitin system [BR:dle04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    TRAF proteins     111179772 (TRAF6) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  zf-TRAF TRAF6_Z2 zf-C3HC4_2 zf-C3HC4 zf-C3HC4_3 zf-RING_2 zf-RING_UBOX zf-C3HC4_4 zf-TRAF_2 zf-RING_5 Spc29 SlyX Tropomyosin_1 DUF3450 DUF4455 PspA_IM30 U-box AAA_13 RNase_Y_N DUF16 EzrA Med21 Spc7 UPF0242 PI3K_P85_iSH2 Laminin_II Myosin_tail_1 Tropomyosin DUF1664 ATG16 TMF_DNA_bd Sina CENP-F_leu_zip Motif Other DBs NCBI-GeneID:  111179772 NCBI-ProteinID:  XP_022439313 UniProt:  A0A2Y9PAB2 LinkDB All DBs Position Unknown AA seq 561 aa AA seqDB search MLLKIFLRRRKRAVDNHLTMSLLHWENSCGSSQSESDCCAAMAASSCGAAAKDESVSGTA STVNLSSSFMEEIQGYDVEFDPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRD AGHKCPVDNEILLENQLFPDNFAKREILSLMVKCPNEGCLHKMELRHLEDHRAHCEFALM NCPQCQRPFQKCQLNIHIVKECPRRQVSCVNCAVSMAFEDKEIHDQNCPLANVICEYCNT MLIREQMPNHYDLDCPTAPVPCTFSTFGCHEKMQRNHLARHLQEDTQSHMRMMAQAVQTL SLAIAPAPQRGMLPCDSASLPRISSGCHSEVQNFQETIQQLEGRLVRQDHQIRELTAKME TQSTYVSELKRTIRTLEDKVAEIEAQQCNGIYIWKIGNFGMHLKSQEEEKPVVIHSPGFY TGKPGYKLCMRLHLQLPTAQRCANYISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSEAP VRQNHEEIMDAKPELLAFQRPTIPRNPKGFGYVTFMHLEALRQRTFIKDDTLLVRCEVST RFDMGSLRREGFQPRSTDLGI NT seq 1686 nt NT seq  +upstreamnt  +downstreamnt atgctactcaaaatctttttgagaagaagaaaaagagcagtcgataatcaccttactatg agtctgctacactgggaaaacagctgtggatccagccagtccgagagcgactgctgtgct gccatggccgccagctcctgtggtgctgcagccaaagatgagagtgtgagtggaactgcc agcacagtgaatctttccagctcttttatggaagagatccagggatatgacgtggaattt gacccacccctggaaagcaagtatgaatgccccatctgcttgatggcattacgggaagca gtgcaaacaccgtgcggccacaggttctgcaaagcctgcatcatcaaatcaataagggat gcaggtcacaaatgtccagttgacaatgaaatactgctggaaaatcaactctttcctgac aattttgcaaaacgagagattctttctctgatggtgaagtgtccaaatgaaggttgtctg cacaagatggaactgaggcatcttgaggatcaccgagcacattgtgagtttgctcttatg aattgtccccaatgccaacgtcccttccaaaaatgccaacttaatattcacattgtcaag gagtgtccaaggagacaggtttcttgtgtaaactgtgctgtatcgatggcatttgaagat aaagagattcatgaccagaactgtcctttggcaaatgtcatctgtgaatactgcaacacc atgctcatcagagaacagatgcctaatcattatgatctagactgtcctacagccccagtt ccatgcacattcagtacttttggttgccatgaaaagatgcagaggaatcacttggcacgc cacctgcaagaggatacccagtcgcacatgagaatgatggcccaggctgttcagacttta agccttgcgatagctcccgcacctcagcgtggcatgctgccatgtgattctgcctctctg ccccggatttcctctgggtgtcactcagaggtccagaatttccaagaaaccattcaacag ttagagggtcgccttgtaagacaagaccatcaaatccgggagctgactgcaaaaatggaa actcagagcacgtatgtaagtgagctaaaacgaactattcgaacccttgaggacaaagtt gctgaaatagaagcacagcagtgcaatggaatttacatctggaagattggcaattttggg atgcacttgaaatctcaagaagaggagaaacctgttgtcattcacagccccggattctac acaggcaaacccggctacaaactatgcatgcgcctgcacctgcagctaccaactgcacag cgctgtgccaactacatatccctcttcgtccacacgatgcaaggagagtatgacagccac ctcccgtggcccttccagggtacgatacgccttaccatccttgatcagtctgaagcacct gtaaggcaaaaccatgaagagataatggacgccaaaccagagctgcttgccttccagaga cccacaatcccacggaaccccaaagggtttggctatgtgacctttatgcatctggaagcc ctaagacaaagaaccttcatcaaggacgacacgttattagtacgctgtgaggtctccacc cgctttgacatgggcagtcttcggagggagggttttcaaccacgaagtactgacttgggg atatag

Delphinapterus leucas (beluga whale): 111184706 Help Entry 111184706         CDS       T05885                                  Gene name TRAF5 Definition (RefSeq) TNF receptor-associated factor 5 isoform X1   KO K09849   TNF receptor-associated factor 5 Organism dle  Delphinapterus leucas (beluga whale) Pathway dle04064   NF-kappa B signaling pathway dle04217   Necroptosis dle04621   NOD-like receptor signaling pathway dle04657   IL-17 signaling pathway dle04668   TNF signaling pathway dle05163   Human cytomegalovirus infection dle05168   Herpes simplex virus 1 infection dle05169   Epstein-Barr virus infection dle05170   Human immunodeficiency virus 1 infection dle05200   Pathways in cancer dle05203   Viral carcinogenesis dle05222   Small cell lung cancer Brite KEGG Orthology (KO) [BR:dle00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     111184706 (TRAF5)    04668 TNF signaling pathway     111184706 (TRAF5)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     111184706 (TRAF5)  09150 Organismal Systems   09151 Immune system    04621 NOD-like receptor signaling pathway     111184706 (TRAF5)    04657 IL-17 signaling pathway     111184706 (TRAF5)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     111184706 (TRAF5)    05203 Viral carcinogenesis     111184706 (TRAF5)   09162 Cancer: specific types    05222 Small cell lung cancer     111184706 (TRAF5)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     111184706 (TRAF5)    05168 Herpes simplex virus 1 infection     111184706 (TRAF5)    05163 Human cytomegalovirus infection     111184706 (TRAF5)    05169 Epstein-Barr virus infection     111184706 (TRAF5)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04121 Ubiquitin system [BR:dle04121]     111184706 (TRAF5) Ubiquitin system [BR:dle04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    TRAF proteins     111184706 (TRAF5) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  zf-TRAF zf-C3HC4 zf-C3HC4_2 zf-C3HC4_4 zf-TRAF_2 zf-RING_UBOX zf-ACC zf-RING_2 DUF4941 zf-RING_6 Med4 DUF4279 Motif Other DBs NCBI-GeneID:  111184706 NCBI-ProteinID:  XP_022449151 UniProt:  A0A2Y9Q0U5 LinkDB All DBs Position Unknown AA seq 616 aa AA seqDB search MACSEEQGGVPCGFIRQNSGNSTSLDFEPDAEYQFVEQLEERYRCAFCRSVLHNPHQTGC GHRFCQHCILSLRELNAVPLCPVDKEVIKSQEVFKDNCCKREVLNLYVFCKNAPGCNAKV ILGRYQRWKVVKWEAGNVAPPQQAHVRFNHTMNEYEASISSFQGIARRTLQVSLPSHTFW NVFQDHLQHCLFQAVQCSNESCREPVLRKDLKEHLSADCPFREEKCLYCKKDVVVINLQN HEENLCPEYPVSCPNKCLQIIPRTEVDEHLAVCPEAEQDCPFKHYGCTVKDKRGNLQEHE HSALRDHMLLVLEKNFQLEEQISDLYKSLEQKESKIQQLAETVKKFEKEFKQFAQLFGKN GTFLSNIQVLASHIDKSAWLEVQVRQLLQMANQQQSKFDLRPLVEAIDTVKQKITLLETH DQRLVVLEGETNKHDAHINIHKAQLNKNEERFKLLESACYNGKLIWKVTDYKLKKKEALD GHTVSIFSQPFYTSRCGYRLCARAYLNGDGSGKGTHLSLYFVVMRGEFDSLLQWPFRQRV TLMLLDQSGKRNHIMETFKADPNSSSFKRPDGEMNIASGCPRFVAHSTLENAKNTYIKDD TLFLKVAVDLTDLEDL NT seq 1851 nt NT seq  +upstreamnt  +downstreamnt atggcttgttctgaggagcaaggaggtgtcccctgtggcttcatccgccagaattctggt aactccacgtctttggactttgagccagatgcagagtaccagtttgtggagcagctggaa gagcgctacagatgtgccttctgccgctcagtgcttcacaacccccaccagacgggctgt gggcaccgcttctgccagcactgcatcctgtccctgagagaattaaacgcagtcccactc tgccctgtagataaggaggtgatcaaatctcaggaggtgtttaaagacaattgctgcaaa agagaagtcctcaatttatatgtattttgcaaaaacgctcctggatgtaatgccaaggtt attctgggacgataccagcggtggaaggttgttaaatgggaagcaggaaacgtggctcca ccacagcaagcccatgtcaggttcaatcacactatgaatgaatacgaggcaagcatctct agcttccaaggaattgctaggaggacgctacaagtttcccttcccagccacacgttttgg aatgtatttcaggaccaccttcagcactgcttattccaagctgtgcagtgctctaatgag agctgtcgggagccagtccttcgcaaagatctgaaagagcatttgagtgcagactgtccg tttcgagaggaaaaatgcctttattgcaaaaaggatgtggtagtcatcaatctacagaat catgaggaaaacttgtgtcctgagtacccagtatcttgtcccaacaagtgtttgcagatt attccaagaactgaggtggatgaacaccttgctgtgtgtcctgaagctgaacaagactgt cctttcaagcactatggctgtactgtaaaggataaacgaggaaacctgcaggagcatgag cattcagccttacgggaccacatgcttctggttttagaaaagaacttccagttagaagaa cagatttctgacttatataagagcctagaacaaaaagaaagtaaaatccagcagctagca gaaaccgtaaagaaattcgaaaaggagttcaagcagtttgcacagttgtttggcaaaaat ggaactttcctctcaaatatacaggttcttgccagtcacattgacaagtccgcttggcta gaagttcaggtgcgtcagttattacaaatggctaaccagcaacaaagtaaatttgatctg aggcctttggtggaagcgattgatacagtgaaacagaaaatcaccctgctagaaacccat gatcaaagattagttgttttggaaggggagactaacaaacatgatgcccacattaatatt cataaagcacagctgaataaaaacgaagagcgatttaagctgctagaaagtgcctgctat aacggaaagctcatctggaaggtcacagactacaagctgaagaagaaggaggcgctggac ggacacacagtatccatcttcagccagcccttctacaccagccggtgtggctacaggctc tgcgctagagcgtacctgaatggggacgggtctgggaaggggacgcacctgtcgttgtac tttgtggtgatgcgaggggagtttgactcactgttgcagtggccattcaggcagagggtg accctgatgcttttggaccaaagtggcaaaaggaaccacattatggagaccttcaaggct gaccccaatagcagcagctttaaaagacccgatggggagatgaacattgcctctggctgt ccacgcttcgtggctcattccactttggagaatgccaagaacacctacattaaagatgac accctgttcttgaaagtggctgtggatttaactgacctggaggatctctaa

Delphinapterus leucas (beluga whale): 111185690 Help Entry 111185690         CDS       T05885                                  Gene name TRAF4 Definition (RefSeq) TNF receptor-associated factor 4   KO K09848   TNF receptor-associated factor 4 Organism dle  Delphinapterus leucas (beluga whale) Pathway dle04657   IL-17 signaling pathway dle05200   Pathways in cancer dle05222   Small cell lung cancer Brite KEGG Orthology (KO) [BR:dle00001]  09150 Organismal Systems   09151 Immune system    04657 IL-17 signaling pathway     111185690 (TRAF4)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     111185690 (TRAF4)   09162 Cancer: specific types    05222 Small cell lung cancer     111185690 (TRAF4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  zf-TRAF zf-C3HC4 zf-C3HC4_2 zf-RING_UBOX zf-Nse zf-C3HC4_4 zf-RING_5 zf-TRAF_2 zf-RING_2 zf-RING_6 zf-C3HC4_3 zf-rbx1 Motif Other DBs NCBI-GeneID:  111185690 NCBI-ProteinID:  XP_022451183 UniProt:  A0A2Y9Q6V6 LinkDB All DBs Position Unknown AA seq 470 aa AA seqDB search MPGFDYKFLEKPKRRLLCPLCGKPMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPEDQLP LDYAKIYPDPELEVQVLGLPIRCIHSEEGCRWSGPLRHLQGHLNTCSFNVVPCPNRCPAK LSRRDLPAHLQHDCPKRRLKCEFCGCDFSGEAFESHEGVCPQESVYCENKCGARMMRRLL AQHATSECPKRTQPCTYCTKEFVFDTIQSHQYQCPRLPVPCPNQCGVGTMAREDLPGHLK DSCSTALVLCPFKDSGCKHRCPKLAMARHVEESVKPHLAMMCALVSRQRQELQELRRELE ELSVGSDGVLIWKIGSYGRRLQEAKAKPNLECFSPAFYTHKYGYKLQVSAFLNGNGSGEG THLSLYIRVLPGAFDNLLEWPFARRVTFSLLDQSDPGLAKPQHVTETFHPDPNWKNFQKP GTWRGSLDESSLGFGYPKFISHQDIRKRNYVRDDAVFIRASVELPRKILS NT seq 1413 nt NT seq  +upstreamnt  +downstreamnt atgcccggctttgactacaagttcttggagaagcccaagcggcggctgctgtgcccgctg tgcgggaagcccatgcgcgagcccgtgcaggtttctacctgcggccaccgcttctgcgac acctgcctgcaggagttcctcagtgaaggagtcttcaagtgccctgaggatcaacttcct ctggactatgccaagatctacccagacccagagctggaggtacaggtactgggcctgcct atccgctgcatccacagtgaggagggctgccgctggagtgggccacttcgccacctacag ggccacctgaatacgtgcagcttcaatgtagtcccctgccccaaccgctgccccgccaag ctgagccgccgggatctgcccgcgcacctgcagcacgactgccccaagaggcgactcaag tgcgagttctgtggctgtgacttcagcggggaggcctttgagagccacgaaggtgtgtgc ccgcaagagagtgtgtactgtgagaacaaatgcggtgcccgcatgatgcggcggctcctg gcccagcatgccacctctgagtgccccaagcgcacccagccttgcacttactgcaccaag gagtttgtctttgacaccatccagagccaccagtaccagtgcccgaggctgcctgtgcca tgccccaaccagtgtggcgtgggcaccatggctcgggaggatctgccgggccacctcaag gacagctgtagcactgccctggtgctgtgcccattcaaagactccggctgcaagcacagg tgccctaagctggcaatggcacggcacgtggaggagagcgtgaagccacatctggccatg atgtgtgccctggtgagccggcaacggcaagagctgcaggagctgcgaagagagctggag gagctctccgtgggcagtgatggcgtgctcatctggaagatcggcagttacgggcgaagg ctgcaggaggccaaagccaagcccaacctcgagtgcttcagccccgccttctacacgcat aagtatggctacaagctgcaggtgtctgcattcctcaatggcaatggcagtggtgagggt acacatctctcgctctacattcgcgtgctgccaggtgcctttgacaatctccttgagtgg ccctttgcccgccgcgtcaccttctccctgctggatcagagcgaccctgggctggctaag ccacagcatgtcactgagacctttcaccctgacccaaactggaagaatttccaaaaacca ggcacttggcggggctccctggatgagagttctctgggctttggttaccccaagttcatc tcccaccaggatatccgcaagcgaaactatgtgcgggatgatgcagtcttcatccgtgcc tctgttgaattgccccgaaagatcctcagctga

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