Delphinapterus leucas (beluga whale): 111178461 Help Entry 111178461         CDS       T05885                                  Symbol JAK1 Name (RefSeq) tyrosine-protein kinase JAK1   KO K11217   Janus kinase 1 [EC:2.7.10.2] Organism dle  Delphinapterus leucas (beluga whale) Pathway dle01521   EGFR tyrosine kinase inhibitor resistance dle04151   PI3K-Akt signaling pathway dle04217   Necroptosis dle04380   Osteoclast differentiation dle04550   Signaling pathways regulating pluripotency of stem cells dle04620   Toll-like receptor signaling pathway dle04621   NOD-like receptor signaling pathway dle04630   JAK-STAT signaling pathway dle04658   Th1 and Th2 cell differentiation dle04659   Th17 cell differentiation dle05140   Leishmaniasis dle05145   Toxoplasmosis dle05152   Tuberculosis dle05160   Hepatitis C dle05161   Hepatitis B dle05162   Measles dle05163   Human cytomegalovirus infection dle05164   Influenza A dle05165   Human papillomavirus infection dle05166   Human T-cell leukemia virus 1 infection dle05167   Kaposi sarcoma-associated herpesvirus infection dle05168   Herpes simplex virus 1 infection dle05169   Epstein-Barr virus infection dle05171   Coronavirus disease - COVID-19 dle05200   Pathways in cancer dle05203   Viral carcinogenesis dle05212   Pancreatic cancer dle05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:dle00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     111178461 (JAK1)    04151 PI3K-Akt signaling pathway     111178461 (JAK1)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     111178461 (JAK1)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     111178461 (JAK1)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     111178461 (JAK1)    04621 NOD-like receptor signaling pathway     111178461 (JAK1)    04658 Th1 and Th2 cell differentiation     111178461 (JAK1)    04659 Th17 cell differentiation     111178461 (JAK1)   09158 Development and regeneration    04380 Osteoclast differentiation     111178461 (JAK1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     111178461 (JAK1)    05203 Viral carcinogenesis     111178461 (JAK1)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     111178461 (JAK1)   09162 Cancer: specific types    05212 Pancreatic cancer     111178461 (JAK1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     111178461 (JAK1)    05161 Hepatitis B     111178461 (JAK1)    05160 Hepatitis C     111178461 (JAK1)    05171 Coronavirus disease - COVID-19     111178461 (JAK1)    05164 Influenza A     111178461 (JAK1)    05162 Measles     111178461 (JAK1)    05168 Herpes simplex virus 1 infection     111178461 (JAK1)    05163 Human cytomegalovirus infection     111178461 (JAK1)    05167 Kaposi sarcoma-associated herpesvirus infection     111178461 (JAK1)    05169 Epstein-Barr virus infection     111178461 (JAK1)    05165 Human papillomavirus infection     111178461 (JAK1)   09171 Infectious disease: bacterial    05152 Tuberculosis     111178461 (JAK1)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     111178461 (JAK1)    05140 Leishmaniasis     111178461 (JAK1)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     111178461 (JAK1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:dle01001]     111178461 (JAK1) Enzymes [BR:dle01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      111178461 (JAK1) Protein kinases [BR:dle01001]  Non-receptor tyrosine kinases   JAK family [OT]    111178461 (JAK1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase Jak1_Phl FERM_F2 FERM_F1 ABC1 SH2 RIO1 Motif Other DBs NCBI-GeneID:  111178461 NCBI-ProteinID:  XP_022436928 UniProt:  A0A2Y9P436 LinkDB All DBs Position Unknown AA seq 1153 aa AA seqDB search MQYLNIKEDCNAMAFCAKMRSSKKTDANLEAPEPGVEVLFYLSDREPLRLGGGEYTAEEL CIKAAQECCISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNWHGTN DNEQSVWRHSPKKQKNSYEKKKVPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN RFHPNDNGNILCYEVMVTGNLGIQWRQKPNVVPVEKEKNKLKRKKLDNKHKKDEEKNKIR EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLCSHEEALSFVSLVDGYFRLTADAH HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT CFEKSELLGVQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFVLK RCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDIMQGEHLGRGTRTHIYSGT LMDYKDDEGTSEEKRIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDV ENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLL LAREGTDSECGPFIKLSDPGIPVTVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFGT TLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRAI MRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNT GEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLPS GSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGD FGLTKAIETDKEYYTVKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYCDSD SSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPEEVYQLMRKCWEFQPSIRTT FQNLIEGFEALLK NT seq 3462 nt NT seq  +upstreamnt  +downstreamnt atgcagtatttaaatataaaagaggactgcaatgccatggctttctgtgctaaaatgagg agctccaagaagactgacgcgaatctggaggcccctgagccaggggtggaagtgctcttc tatctgtcggacagggagcccctccggttgggcggcggagagtacacagcggaggagctg tgcatcaaggcggcgcaggaatgctgtatatctcctctgtgtcacaacctctttgccctg tatgatgagaacaccaagctctggtatgctccgaatcgcaccatcaccgtcgacgacaag atgtcactccggctccactaccggatgaggttctatttcaccaactggcacgggaccaat gataacgagcagtcagtatggcgacattctccaaagaagcagaagaatagctacgagaaa aaaaaagttccagatgcaacccctctccttgacgccagctcattggagtatctgtttgct cagggacagtatgatttggtcaaatgcctggctcccattcgagaccccaagacggagcag gatgggcatgatattgagaacgagtgtctgggaatggccgtcctggccatctcccactat gccatgatgaagaagatgcagttgccagaacttcccaaggacatcagctacaagcgatat ataccagaaacattgaataagtccatcagacagaggaaccttctcaccaggatgcggata aataatgttttcaaggatttcctaaaggagtttaacaacaagaccatttgtgacagcagt gtgtccacacatgacctgaaggtgaaatacctggctaccttggaaactttgacaaaacat tatggtgctgaaatatttgagacttccatgctactgatttcatcagaaaatgagatgaat cggttccatccgaatgataatggaaacattctctgctatgaagtgatggtgactggaaat cttggaatccagtggaggcagaaaccaaatgttgttcctgttgaaaaggaaaaaaataaa ctgaaacggaaaaaactggacaataaacacaagaaggatgaggagaaaaataaaatccgg gaagagtggaacaatttttcttacttccctgagatcactcacattgtaatcaaggagtct gtggtcagcattaataagcaggacaacaaaaaaatggaactgaagctctgttcccacgag gaggccttgtcctttgtgtccctcgtggacggctacttccggctcacagcagatgcccat cattacctctgcaccgacgtggctcccccgttgatcgtccacaacatacagaatggctgt cacggtccaatctgcacagaatatgccatcaataagttgcggcaagaaggaagcgaggag ggaatgtacgtgctgcggtggagctgcaccgacttcgacaacatcctcatgaccgtcact tgctttgaaaagtctgagttgctgggtgtccagaagcagttcaagaactttcagattgag gtgcagaagggccgctacagcctgcatggctcagaccgaagcttccccagccttggagac ctcatgagccacctgaagaagcagatcctgcgcacggacaacatcagctttgtgctgaag cgctgctgccagcccaagccccgagaaatctccaatctgctggtggccaccaagaaagcc caggagtggcagcctgtctaccccatgagccagctgagttttgatcggatcctcaagaaa gatattatgcagggcgagcaccttgggagaggcacgcggacacacatctactctgggacc ctcatggattacaaggatgacgaaggaacttccgaagagaagagaataaaagtgatcctc aaagtcttagaccccagccacagggacatttctctggccttctttgaggcagccagcatg atgagacaggtctcccataaacacatcgtgtacctctatggcgtttgtgtccgagacgtg gagaatatcatggtggaagagtttgtggagggagggcccctggatctcttcatgcaccgg aaaagtgatgtcctcaccacaccctggaagttcaaagttgccaaacagctggccagcgcc ctgagttacttggaggataaagatctggtccacggaaatgtgtgcactaaaaacctcctc ctggcccgcgagggcactgacagcgagtgcggccccttcatcaagctcagtgaccccggc atccccgtcactgtgctgtccaggcaagagtgcatagaacgaatcccatggatcgctcct gagtgtgttgaagactccaagaacctgagtgtggccgctgacaagtggagctttggaacc acgctctgggagatctgctacaatggcgagatccccttgaaagacaagacactgattgag aaagagaggttctatgaaagccggtgcaggccagtgaccccgtcttgtaaggagctagct gaccttatgacccgctgcatgaactacgaccccaaccagagacccttcttccgagccatc atgagagacatcaataagctggaggagcagaatccagacatcgtatcagaaaaaaagcca gcaactgaagtggatcccacacattttgaaaagcggttcttaaagaggatccgtgacttg ggagagggccactttgggaaggtcgagctctgcaggtatgaccctgagggggacaataca ggggagcaggtggccgtcaaatccctgaagcctgagagcggagggaaccacatagctgat ctgaagaaggaaattgaaatcttaagaaacctttatcatgagaacattgtgaagtataaa ggcatctgcacagaagacggaggaaacggtattaagctcatcatggaatttctgccttca ggaagtcttaaggagtatcttccaaagaataagaacaaaattaacctcaaacagcagtta aaatatgccgttcagatttgtaaggggatggactatttgggttctcggcaatacgttcac cgtgacttagcagcaagaaatgtccttgttgagagtgaacaccaagtgaaaattggggac tttggtctaaccaaagccattgaaactgataaggagtactacacagtcaaggacgatcgg gacagccctgtgttttggtatgctccagaatgtttaattcagtgtaagttttatatcgcc tctgatgtctggtcttttggagtaactctgcatgagctgcttacttactgtgattcagat tccagtcccatggcgttgttcctgaaaatgataggcccaactcatggccagatgacagta acaagacttgtgaatacattaaaagaaggaaaacgtttgccttgtccacctaactgtcca gaagaggtttatcaacttatgagaaaatgctgggaattccaaccatccattcggacaacc tttcagaaccttattgagggatttgaagcgcttctaaaataa

DBGET integrated database retrieval system