KEGG T05885: 111179463

KEGG Orthology (KO) [BR:dle00001]
09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    111179463 (PLCG2)
09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    111179463 (PLCG2)
   04014 Ras signaling pathway
    111179463 (PLCG2)
   04370 VEGF signaling pathway
    111179463 (PLCG2)
   04064 NF-kappa B signaling pathway
    111179463 (PLCG2)
   04066 HIF-1 signaling pathway
    111179463 (PLCG2)
   04020 Calcium signaling pathway
    111179463 (PLCG2)
   04070 Phosphatidylinositol signaling system
    111179463 (PLCG2)
   04072 Phospholipase D signaling pathway
    111179463 (PLCG2)
09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    111179463 (PLCG2)
   04613 Neutrophil extracellular trap formation
    111179463 (PLCG2)
   04625 C-type lectin receptor signaling pathway
    111179463 (PLCG2)
   04650 Natural killer cell mediated cytotoxicity
    111179463 (PLCG2)
   04662 B cell receptor signaling pathway
    111179463 (PLCG2)
   04664 Fc epsilon RI signaling pathway
    111179463 (PLCG2)
   04666 Fc gamma R-mediated phagocytosis
    111179463 (PLCG2)
   04670 Leukocyte transendothelial migration
    111179463 (PLCG2)
   04062 Chemokine signaling pathway
    111179463 (PLCG2)
  09152 Endocrine system
   04935 Growth hormone synthesis, secretion and action
    111179463 (PLCG2)
   04919 Thyroid hormone signaling pathway
    111179463 (PLCG2)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    111179463 (PLCG2)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    111179463 (PLCG2)
  09158 Development and regeneration
   04360 Axon guidance
    111179463 (PLCG2)
   04380 Osteoclast differentiation
    111179463 (PLCG2)
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    111179463 (PLCG2)
   05206 MicroRNAs in cancer
    111179463 (PLCG2)
   05205 Proteoglycans in cancer
    111179463 (PLCG2)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    111179463 (PLCG2)
   05214 Glioma
    111179463 (PLCG2)
   05223 Non-small cell lung cancer
    111179463 (PLCG2)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    111179463 (PLCG2)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    111179463 (PLCG2)
   05171 Coronavirus disease - COVID-19
    111179463 (PLCG2)
   05167 Kaposi sarcoma-associated herpesvirus infection
    111179463 (PLCG2)
   05169 Epstein-Barr virus infection
    111179463 (PLCG2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    111179463 (PLCG2)
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:dle04131]
    111179463 (PLCG2)
Enzymes [BR:dle01000]
3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     111179463 (PLCG2)
Membrane trafficking [BR:dle04131]
Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    111179463 (PLCG2)
Endocytosis
  Macropinocytosis
   Phospholipase C
    111179463 (PLCG2)

SSDB

Motif

Pfam:

PI-PLC-X SH2 PI-PLC-Y C2 SH3_1 SH3_9 PH SH3_2 PH_12 PH_14 EF-hand_like

Other DBs

NCBI-GeneID:

111179463

NCBI-ProteinID:

XP_022438794

UniProt:

A0A2Y9NXP3

LinkDB

Position

Unknown

AA seq 1265 aa
MSTTVNVDALPEYEKSQIKRALELGTVMTVFSFRKSTPERRTVQVIMETQQVAWSKTADK
IEGFLDIMEIKEIRPGKNSKDFERAKAVRQKEECCFTILYGTQFVLSTLSLAADSKEDAT
KWLSGLKILHQEVMNASTPTIIESWLRKQIYSVDQTRRNSISLRELKTILPLVNFKVSSA
KFLKDKFVEIGAHKDELSFEQFHLFYKKLMFEQQKLILDEFKKDSSVFILGNTDRPDASA
VHLHDFQRFLLHEQQELWAQDLNKVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSRENS
IWDEKYDVVDVQDMNNPLSHYWISSSHNTYLTGDQLRSESSPEAYIRCLRMGCRCIELDC
WDGPDGKPIIYHGWTRTTKIKFDDVVQAIKDHAFVTSSFPVILSIEEHCCLQQQRHMARV
FKEAFGDLLLTKPTEASADQLPSPSQLREKIIIKHKKLGPRGDVDVNVEDKKDEHRQQGE
LYMWDSIDQRWTRHYCAIADAKLSFSDDIEQTTEGEQPPDIAPTELHFGEKWFHKKVEKR
TSAEKLLQEYCAETGGKDGTFLVRESETYPNDYTLSFWRSGRVQHCRIRSTMEGGTLKYY
LTDNLMFTSIYALIQHYSETHLRCAEFELRLTDPVPNPSPHESKPWYYDGLSRGEAEDML
MRVPRDGAFLIRKREGSDSYAITFRARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYY
EKHALYRKMKLRYPVTPELLERYNMERDINSLYDVSRMYVDPSEISPSMPQRTVKALYDY
KAKRNDELSFCRGALIHNVSKEPGGWWKGDYGTRIQQYFPSNYVEDISTADGEDLEKQII
EDNPLGSLCRGILDLNTYNVVKAPQGKNQKPFVFILEPKKQGDPPVEFATDKVEELFEWF
QSIREITWKIDTKENNMKYWEKNQSIAIELSDLVVYCKPTSKTKDNLENPDFREIRSFVE
TKADSIVRQKPNDLLKYNQKGLTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTPDKY
LQMNHALFSLNGRTGYVLQPESMRAEKYDPMPPESQRKILMTLTVKVLGARHLPKPGRSI
ACPFVEVEICGAEYDNNKFKTTVVNDNGLSPVWAPTQEKVTFEIYDPNLAFLRFVVYEED
MFSDPNFLAHATFPIKGIKSGFRSVPLKNGYSEDMELASLLVFCEMRPVLESEEELYSSC
RQLRRRQEELNNQLFLYDTHQNLRSANRDALVREFNVNENQLQLYQEKCNRRLREKRVSN
SKFYS

NT seq 3798 nt +upstreamnt +downstreamnt
atgagcaccacggtcaacgtggacgcccttccggagtacgagaagagtcagatcaagagg
gccctggagctgggcacggtgatgacggtgttcagcttccgcaagtccaccccggagcgg
aggactgtccaggtgatcatggagacccagcaggtggcctggagcaagacggccgataag
atcgagggcttcctggatatcatggaaataaaggaaatccgcccagggaagaactccaag
gattttgagcgtgcgaaagcagtccgtcagaaggaagagtgctgcttcaccatcttgtat
ggcacccagttcgtcctcagcacgctcagcttagcagccgactctaaagaagatgcaact
aagtggctctctggcttgaagatcttgcaccaggaagtgatgaacgcatccacccccacc
atcattgagagttggttgcgaaagcagatttattctgtggatcagaccagaagaaacagc
atcagcctccgagagttgaagaccatcttgcccctggtcaacttcaaagtgagcagcgcc
aagttcctcaaagataagttcgtggaaataggagcacacaaagatgaactcagctttgaa
cagttccatctcttctataaaaaacttatgtttgaacagcagaaattgattcttgacgaa
ttcaaaaaggattcctccgtgttcatcttgggcaacaccgaccggccggatgcctccgct
gttcacctgcatgacttccagcggtttctcttacatgaacagcaggagctttgggcccag
gatctgaacaaagtccgtgagcggatgacaaagttcattgatgacacgatgagagaaact
gccgagcccttcctgtttgtggatgagttcctcacgtacctgttttcccgggagaacagc
atttgggatgagaagtatgacgtggtggatgtgcaggacatgaacaaccccttgtctcat
tactggatctcctcatcacataacacgtacctcacgggtgaccagcttcggagcgagtcg
tccccggaggcctatatccgctgtctgcggatgggctgccgctgcattgagctggactgc
tgggacgggcccgacgggaagcccatcatctaccacggctggacgcggaccaccaagatc
aagtttgatgacgtcgtgcaggccatcaaggaccatgcctttgtcacctcgagcttcccc
gtgatcctgtccatcgaggagcactgctgcctgcagcagcagcgccacatggccagggtg
ttcaaggaggcgttcggcgacctgctgctgaccaagcccacggaggccagtgccgaccag
ctgccgtcgcccagccagctgcgggagaagatcatcatcaagcataagaagctgggcccc
cgaggcgacgtggatgtcaacgtggaggacaagaaagatgaacacaggcagcagggtgaa
ctgtacatgtgggattccatcgaccagcgatggactcggcactactgcgccattgctgac
gccaagctgtccttcagcgacgacattgaacagactacggaaggtgaacagcccccggat
atagcccccacggagctgcattttggggagaagtggttccacaagaaggtggagaagagg
acaagcgccgagaagctgctgcaggaatactgcgccgagacggggggcaaggatgggacc
ttcttggtgcgggagagcgagacgtaccccaatgactacaccctgtccttctggcggtcg
ggccgcgtccagcactgccggatccgctccaccatggagggcgggaccctgaagtattac
ctgactgacaacctcatgttcaccagcatctatgccctcatccagcactacagcgagacg
cacctgcgctgtgccgagttcgagctccggctcaccgacccagttcccaaccccagcccg
cacgagtcgaagccgtggtactatgacgggctgagccgcggagaagcggaggacatgctg
atgagggttccccgggatggggccttcctgatccggaagcgggaaggttctgactcctac
gccatcaccttcagggccaggggcaaggtgaagcactgtcgcatcaaccgggacggccgg
cacttcgtgctgggcacctccgcctacttcgagagcctcgtggagctggtcagctactac
gagaagcacgcactctaccggaagatgaaactgcgctaccccgtgacccccgagctcctg
gagcgctacaatatggaaagagatataaactccctctatgatgtcagcaggatgtatgtg
gatcccagtgaaatcagcccttccatgcctcagagaaccgtgaaagctctgtatgactac
aaagccaagcgaaacgatgagctgagcttctgccgtggcgccctcatccacaatgtctcc
aaggagcctgggggctggtggaaaggagactacggaaccagaatccagcagtacttcccg
tccaattacgttgaagacatttcaacagctgacggggaggacctggaaaagcagattatt
gaagacaatcccttagggtctctttgcagaggaatactggatctcaacacctataatgtt
gtaaaggccccacaggggaagaaccagaagcctttcgtctttatcttggagcccaagaag
cagggtgaccctccggtggagtttgccacagacaaggtggaggagctgtttgagtggttc
cagagcatccgggagatcacctggaagatcgacaccaaggagaacaacatgaagtactgg
gagaagaaccagtccatcgccatcgagctctcggacctggtcgtctactgcaaaccaacc
agcaagaccaaggacaacctagaaaaccccgacttccgagaaatccgctccttcgtggag
acaaaggctgacagcatcgtcagacagaaacccaacgatctcttgaaatacaatcaaaag
ggcctgacccgcgtttaccccaagggacagcgggtggactcctccaactacgaccccttc
cgcctctggctgtgtggctcccagatggtggcactcaatttccagacaccagataagtac
ctgcagatgaatcacgccctgttttccctcaatgggcggactggctacgtcctgcagccc
gagagcatgagggcggagaagtacgaccccatgccgcccgagtcccagaggaagatcctg
atgactctgacggtcaaggttctgggggctcgtcatctccccaaacctggacgaagtatt
gcatgtccctttgtggaggtggaaatatgcggagccgaatatgacaacaacaagttcaaa
acaacagttgtgaatgacaacggcctaagccctgtttgggctccgacacaggagaaggtg
acatttgaaatttatgacccaaacctcgcgtttctacgctttgtggtttacgaggaagat
atgttcagcgatcccaactttctcgcgcatgccactttccccattaaaggaatcaaatca
ggatttagatctgttcctctgaagaacggctacagtgaagacatggagctggcttccctc
ctggttttctgtgagatgcggccagtcctggagagcgaagaggagctttactcctcctgc
cgccagctgcggaggcggcaagaagaactgaacaaccagctctttctgtacgacacacac
cagaacttgcgcagcgccaaccgggatgccctggtcagagagttcaacgtcaacgagaac
cagctgcagctgtaccaggagaagtgcaaccgcaggttaagagagaagagagtcagcaac
agcaagttctactcatag

Delphinapterus leucas (beluga whale): 111184170

Entry

111184170 CDS T05885

Gene name

PLCG1

Definition

(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1

K01116

phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]

Organism

dle Delphinapterus leucas (beluga whale)

Pathway

dle00562

Inositol phosphate metabolism

dle01100

Metabolic pathways

dle01521

EGFR tyrosine kinase inhibitor resistance

dle04012

ErbB signaling pathway

dle04014

Ras signaling pathway

dle04015

Rap1 signaling pathway

dle04020

Calcium signaling pathway

dle04062

Chemokine signaling pathway

dle04064

NF-kappa B signaling pathway

dle04066

HIF-1 signaling pathway

dle04070

Phosphatidylinositol signaling system

dle04072

Phospholipase D signaling pathway

dle04360

Axon guidance

dle04370

VEGF signaling pathway

dle04613

Neutrophil extracellular trap formation

dle04650

Natural killer cell mediated cytotoxicity

dle04658

Th1 and Th2 cell differentiation

dle04659

Th17 cell differentiation

dle04660

T cell receptor signaling pathway

dle04664

Fc epsilon RI signaling pathway

dle04666

Fc gamma R-mediated phagocytosis

dle04670

Leukocyte transendothelial migration

dle04722

Neurotrophin signaling pathway

dle04750

Inflammatory mediator regulation of TRP channels

dle04919

Thyroid hormone signaling pathway

dle04933

AGE-RAGE signaling pathway in diabetic complications

dle04935

Growth hormone synthesis, secretion and action

dle05012

Parkinson disease

dle05022

Pathways of neurodegeneration - multiple diseases

dle05135

Yersinia infection

dle05167

Kaposi sarcoma-associated herpesvirus infection

dle05170

Human immunodeficiency virus 1 infection

dle05171

Coronavirus disease - COVID-19

dle05200

Pathways in cancer

dle05205

Proteoglycans in cancer

dle05206

MicroRNAs in cancer

dle05214

Glioma

dle05223

Non-small cell lung cancer

dle05225

Hepatocellular carcinoma

dle05231

Choline metabolism in cancer

dle05235

PD-L1 expression and PD-1 checkpoint pathway in cancer

Module

dle_M00130

Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4

Brite

KEGG Orthology (KO) [BR:dle00001]
09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    111184170 (PLCG1)
09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    111184170 (PLCG1)
   04014 Ras signaling pathway
    111184170 (PLCG1)
   04015 Rap1 signaling pathway
    111184170 (PLCG1)
   04370 VEGF signaling pathway
    111184170 (PLCG1)
   04064 NF-kappa B signaling pathway
    111184170 (PLCG1)
   04066 HIF-1 signaling pathway
    111184170 (PLCG1)
   04020 Calcium signaling pathway
    111184170 (PLCG1)
   04070 Phosphatidylinositol signaling system
    111184170 (PLCG1)
   04072 Phospholipase D signaling pathway
    111184170 (PLCG1)
09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    111184170 (PLCG1)
   04650 Natural killer cell mediated cytotoxicity
    111184170 (PLCG1)
   04660 T cell receptor signaling pathway
    111184170 (PLCG1)
   04658 Th1 and Th2 cell differentiation
    111184170 (PLCG1)
   04659 Th17 cell differentiation
    111184170 (PLCG1)
   04664 Fc epsilon RI signaling pathway
    111184170 (PLCG1)
   04666 Fc gamma R-mediated phagocytosis
    111184170 (PLCG1)
   04670 Leukocyte transendothelial migration
    111184170 (PLCG1)
   04062 Chemokine signaling pathway
    111184170 (PLCG1)
  09152 Endocrine system
   04935 Growth hormone synthesis, secretion and action
    111184170 (PLCG1)
   04919 Thyroid hormone signaling pathway
    111184170 (PLCG1)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    111184170 (PLCG1)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    111184170 (PLCG1)
  09158 Development and regeneration
   04360 Axon guidance
    111184170 (PLCG1)
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    111184170 (PLCG1)
   05206 MicroRNAs in cancer
    111184170 (PLCG1)
   05205 Proteoglycans in cancer
    111184170 (PLCG1)
   05231 Choline metabolism in cancer
    111184170 (PLCG1)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    111184170 (PLCG1)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    111184170 (PLCG1)
   05214 Glioma
    111184170 (PLCG1)
   05223 Non-small cell lung cancer
    111184170 (PLCG1)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    111184170 (PLCG1)
   05022 Pathways of neurodegeneration - multiple diseases
    111184170 (PLCG1)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    111184170 (PLCG1)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    111184170 (PLCG1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    111184170 (PLCG1)
   05171 Coronavirus disease - COVID-19
    111184170 (PLCG1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    111184170 (PLCG1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    111184170 (PLCG1)
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:dle04131]
    111184170 (PLCG1)
Enzymes [BR:dle01000]
3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     111184170 (PLCG1)
Membrane trafficking [BR:dle04131]
Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    111184170 (PLCG1)
Endocytosis
  Macropinocytosis
   Phospholipase C
    111184170 (PLCG1)

SSDB

Motif

Pfam:

PI-PLC-X SH2 PI-PLC-Y SH3_1 PH C2 SH3_9 SH3_2 PH_12 GDPD PH_9

Other DBs

NCBI-GeneID:

111184170

NCBI-ProteinID:

XP_022448104

UniProt:

A0A2Y9PMG8

LinkDB

Position

Unknown

AA seq 1291 aa
MAGAASPCANGCGPGAPSDAEVLHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQI
TWSRGADKIEGAIDIREIKEIRPGKTSRDFDRYQEDPAFRPDQSHCFVILYGMEFRLKTL
SLQATSEDEVNMWIKGLTWLMEDTLQAATPLQIERWLRKQFYSVDRNREDRISAKDLKNM
LSQVNYRVPNMRFLRERLTDLEQRTSDITYGQFAQLYRSLMYSAQKTMDLPFLEASALRA
GERPELCRVSLPEFQQFLLEYQGELWAVDRLQVQEFMLSFLRDPLREIEEPYFFLDEFVT
FLFSKENSIWNSQLDAVCPDAMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMG
CRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIA
QQRNMAQYFKKVLGDTLLTKPVDIAADGLPSPSQLKRKILIKHKKLAEGSAYEEVPTSVM
YSENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGNEDEEEPKEASG
STELHSNEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFW
RNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMRLSEPVPQT
NAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQE
GQTVMLGNSEFDSLVDLVSYYEKHPLYRKMKLRYPINEEALEKIGTAEPDYGALYEGRNP
GFYVEANPMPTFKCAVKALFDYKAQREDELTFTKSAIIQNVEKQEGGWWRGDYGGKKQLW
FPSNYVEEMVSPAALEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEGKNNRPFVFSIS
MASVAHWSLDVAADSQEELQDWVKKIREVAQTADARLTEGKMMERRKKIALELSELVVYC
RPVPFDEEKIGTERACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSRIYPKGQRLDS
SNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFLAGGHCGYVLQPSIMREEAFDPFDKS
SLRGLEPCAICIEVLGARHLPKNGRGIVCPFVELEVAGAEYDSAKQKTEFVVDNGLNPMW
PAKPFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYRAVPLKNNYSEDL
ELASLLVKVDVFPAKQENGDLSPFGGASLRERGCDASGQLFHGRAREGSFEARYQQPFED
FRISQEHLADHFDSRERRAPRRTRVNGDNRL

NT seq 3876 nt +upstreamnt +downstreamnt
atggcgggcgccgcgtccccctgcgccaacggctgcgggcccggcgcgccctcggacgcc
gaggtgctgcacctctgccgcagcctcgaggtgggcaccgttatgactttgttctactcc
aagaagtcgcagcggcccgagcggaagaccttccaggtcaagctggagacgcggcagatc
acgtggagccgtggcgccgacaagatcgagggggccattgacattcgagaaatcaaggag
atccgcccggggaagacctcacgggacttcgatcgctaccaagaggatcctgcttttcga
ccggaccagtcacactgctttgtcatcctgtatggaatggaattccgcctgaagaccctg
agcctgcaagctacgtctgaggacgaagtgaacatgtggatcaagggcctgacttggctg
atggaggatacgttgcaggcagccacacccttgcagattgagaggtggctgcggaagcag
ttctactcagtggaccggaatcgtgaggatcgtatatcagccaaggacctgaagaacatg
ctgtcccaggtcaactaccgggtccccaacatgcgcttcctccgagagcggctgacggac
ctggagcagcgcaccagcgacatcacctacgggcagtttgctcagctgtaccgcagcctt
atgtacagcgcccagaagacgatggacctccccttcctggaagccagtgccctgagggcg
ggggagcggccggagctctgccgggtgtcccttcctgagttccagcagttcctcctcgag
taccagggggagctatgggctgtcgaccggctccaggtgcaggagttcatgctcagcttc
cttcgagaccccttgcgagagatcgaggagccttacttcttcctggatgagttcgtcacc
ttcctgttctccaaggagaacagcatatggaattcgcagctggacgccgtgtgccccgac
gccatgaacaaccccctgtcccactactggatctcctcctcgcacaacacgtacctgacc
ggggaccagttttccagcgagtcctccctggaagcctacgcccgctgcctgcggatgggc
tgccgctgcatcgagttggactgctgggatggtccagacgggatgccagtcatttaccac
ggacacaccctgaccaccaagatcaagttctcagacgtcctgcacaccatcaaggagcac
gcctttgtggcctcagagtacccggtcatcttgtccatcgaggaccattgcagcatcgcc
cagcagaggaacatggcccagtacttcaagaaggtgctcggggacacactcctcaccaag
cccgtggacattgctgctgacgggctcccctcacccagccagctcaagaggaagatcctc
atcaagcacaagaagctggctgagggcagtgcctatgaagaggtgcctacgtccgtgatg
tactctgagaacgacatcagcaactccatcaagaatggcatcctctacctggaggacccc
gtgaatcacgagtggtatccccactacttcgttctgaccagtagcaagatctactactcc
gaggagaccagcagtgaccagggcaacgaggacgaggaggagcccaaggaggccagtggc
agcacagagctgcactccaatgagaagtggtttcacgggaagctcggggcaggacgggat
gggcggcacattgccgagcgcctgctcacagagtactgcatcgagaccggggcccccgac
ggctccttcctcgtgcgcgagagcgagaccttcgtgggcgactacaccctctccttctgg
cggaacggcaaagtccagcactgccggatccactcccggcaggacgcagggacccccaag
ttcttcctgactgacaacctcgtcttcgactcactctatgacctcatcacacactaccag
caggtgcccctgcgctgcaacgaatttgagatgcgcctctcagagcccgtcccgcagacc
aacgcccacgagagcaaagagtggtaccacgcgagcctgaccagagcgcaggccgagcac
atgctgatgcgcgtcccccgggacggggccttcctggtgcggaaacggaatgagcccaac
tcctacgccatctccttccgggctgagggcaagatcaagcactgccgcgtacagcaggag
ggccagaccgtgatgctgggcaactcagagtttgacagcctcgtggacctcgtcagctac
tacgagaagcatcccctgtaccgcaagatgaagctacgctatcccatcaacgaggaggca
ctggagaagatcggcacagcggagcctgactatggggccctgtatgagggccgcaacccc
ggcttctacgtggaggcgaaccccatgccaactttcaagtgcgccgtcaaagctctcttc
gactacaaggcccagagagaggacgagctgactttcaccaagagcgccatcatccagaac
gtggagaagcaggaaggaggctggtggcgtggtgactatggtgggaagaagcagctgtgg
ttcccgtcgaactacgtggaagagatggtcagccctgcggccctggaacctgagagggag
cacttggacgagaacagccccctgggggacttgctgcggggggtcttggatgtgccggct
tgtcagatagccatccgtcctgagggcaagaacaaccggcccttcgtcttctccatcagc
atggcatcggtggcacactggtccctagatgtggctgccgactcacaggaggagctgcag
gactgggtgaaaaagatccgggaagtggcccagaccgcggatgccaggctcactgagggg
aagatgatggagcggaggaagaagatcgccctggagctctccgagcttgtcgtctactgc
cggcctgttcccttcgacgaagagaagatcggcacagaacgcgcctgctaccgggacatg
tcgtccttcccggaaaccaaggctgagaagtacgtgaacaaggccaaaggcaagaagttc
ctccagtacaaccggctgcagctctcccgcatctaccccaagggccagcggctggactcc
tccaattacgaccccttgcccatgtggatctgtggcagtcagctggtagccctcaacttc
caaaccccagacaagcctatgcagatgaaccaggccctcttcctggccggcgggcactgt
ggctacgtgctgcagccgagcatcatgcgcgaggaggccttcgacccctttgacaagagc
agcctccgtgggctggagccgtgcgccatctgcatcgaggtgctgggggcccggcacctg
ccgaagaacggccgaggcatcgtgtgtccgttcgtggagcttgaggtggccggtgctgag
tatgacagcgccaagcagaagaccgagtttgtggtggacaacggactgaaccccatgtgg
ccagccaagcccttccacttccagatcagtaaccccgaattcgccttcctgcgctttgtg
gtgtatgaggaagacatgtttagtgaccagaacttcctggctcaggccaccttcccggtg
aagggcctgaagacaggatacagagctgtgcctttgaagaacaactatagtgaggacctg
gagttggcctccctgctcgtcaaggtcgacgttttccctgccaagcaggagaacggcgac
ctcagtccctttgggggtgcgtccctgcgggagcggggctgcgacgcctcgggccagctg
tttcacggccgggcccgggaaggctccttcgaagctcgctaccagcagccatttgaggac
ttccgcatctcccaggagcatctcgccgaccattttgacagtcgggaacgaagggccccg
cgaaggactcgggtcaatggagacaaccgcctctag

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