KEGG   Delphinapterus leucas (beluga whale): 111180981
Entry
111180981         CDS       T05885                                 

Gene name
PRKCG
Definition
(RefSeq) protein kinase C gamma type isoform X1
  KO
K19663  classical protein kinase C gamma type [EC:2.7.11.13]
Organism
dle  Delphinapterus leucas (beluga whale)
Pathway
dle01521  EGFR tyrosine kinase inhibitor resistance
dle04010  MAPK signaling pathway
dle04012  ErbB signaling pathway
dle04014  Ras signaling pathway
dle04015  Rap1 signaling pathway
dle04020  Calcium signaling pathway
dle04066  HIF-1 signaling pathway
dle04070  Phosphatidylinositol signaling system
dle04071  Sphingolipid signaling pathway
dle04150  mTOR signaling pathway
dle04270  Vascular smooth muscle contraction
dle04310  Wnt signaling pathway
dle04370  VEGF signaling pathway
dle04510  Focal adhesion
dle04540  Gap junction
dle04613  Neutrophil extracellular trap formation
dle04650  Natural killer cell mediated cytotoxicity
dle04666  Fc gamma R-mediated phagocytosis
dle04670  Leukocyte transendothelial migration
dle04713  Circadian entrainment
dle04720  Long-term potentiation
dle04723  Retrograde endocannabinoid signaling
dle04724  Glutamatergic synapse
dle04725  Cholinergic synapse
dle04726  Serotonergic synapse
dle04727  GABAergic synapse
dle04728  Dopaminergic synapse
dle04730  Long-term depression
dle04750  Inflammatory mediator regulation of TRP channels
dle04911  Insulin secretion
dle04916  Melanogenesis
dle04918  Thyroid hormone synthesis
dle04919  Thyroid hormone signaling pathway
dle04921  Oxytocin signaling pathway
dle04925  Aldosterone synthesis and secretion
dle04928  Parathyroid hormone synthesis, secretion and action
dle04929  GnRH secretion
dle04935  Growth hormone synthesis, secretion and action
dle04960  Aldosterone-regulated sodium reabsorption
dle04961  Endocrine and other factor-regulated calcium reabsorption
dle04970  Salivary secretion
dle04971  Gastric acid secretion
dle04972  Pancreatic secretion
dle05017  Spinocerebellar ataxia
dle05022  Pathways of neurodegeneration - multiple diseases
dle05031  Amphetamine addiction
dle05032  Morphine addiction
dle05143  African trypanosomiasis
dle05146  Amoebiasis
dle05161  Hepatitis B
dle05163  Human cytomegalovirus infection
dle05170  Human immunodeficiency virus 1 infection
dle05171  Coronavirus disease - COVID-19
dle05200  Pathways in cancer
dle05205  Proteoglycans in cancer
dle05206  MicroRNAs in cancer
dle05214  Glioma
dle05223  Non-small cell lung cancer
dle05225  Hepatocellular carcinoma
dle05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:dle00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    111180981 (PRKCG)
   04012 ErbB signaling pathway
    111180981 (PRKCG)
   04014 Ras signaling pathway
    111180981 (PRKCG)
   04015 Rap1 signaling pathway
    111180981 (PRKCG)
   04310 Wnt signaling pathway
    111180981 (PRKCG)
   04370 VEGF signaling pathway
    111180981 (PRKCG)
   04066 HIF-1 signaling pathway
    111180981 (PRKCG)
   04020 Calcium signaling pathway
    111180981 (PRKCG)
   04070 Phosphatidylinositol signaling system
    111180981 (PRKCG)
   04071 Sphingolipid signaling pathway
    111180981 (PRKCG)
   04150 mTOR signaling pathway
    111180981 (PRKCG)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    111180981 (PRKCG)
   04540 Gap junction
    111180981 (PRKCG)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    111180981 (PRKCG)
   04650 Natural killer cell mediated cytotoxicity
    111180981 (PRKCG)
   04666 Fc gamma R-mediated phagocytosis
    111180981 (PRKCG)
   04670 Leukocyte transendothelial migration
    111180981 (PRKCG)
  09152 Endocrine system
   04911 Insulin secretion
    111180981 (PRKCG)
   04929 GnRH secretion
    111180981 (PRKCG)
   04921 Oxytocin signaling pathway
    111180981 (PRKCG)
   04935 Growth hormone synthesis, secretion and action
    111180981 (PRKCG)
   04918 Thyroid hormone synthesis
    111180981 (PRKCG)
   04919 Thyroid hormone signaling pathway
    111180981 (PRKCG)
   04928 Parathyroid hormone synthesis, secretion and action
    111180981 (PRKCG)
   04916 Melanogenesis
    111180981 (PRKCG)
   04925 Aldosterone synthesis and secretion
    111180981 (PRKCG)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    111180981 (PRKCG)
  09154 Digestive system
   04970 Salivary secretion
    111180981 (PRKCG)
   04971 Gastric acid secretion
    111180981 (PRKCG)
   04972 Pancreatic secretion
    111180981 (PRKCG)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    111180981 (PRKCG)
   04961 Endocrine and other factor-regulated calcium reabsorption
    111180981 (PRKCG)
  09156 Nervous system
   04724 Glutamatergic synapse
    111180981 (PRKCG)
   04727 GABAergic synapse
    111180981 (PRKCG)
   04725 Cholinergic synapse
    111180981 (PRKCG)
   04728 Dopaminergic synapse
    111180981 (PRKCG)
   04726 Serotonergic synapse
    111180981 (PRKCG)
   04720 Long-term potentiation
    111180981 (PRKCG)
   04730 Long-term depression
    111180981 (PRKCG)
   04723 Retrograde endocannabinoid signaling
    111180981 (PRKCG)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    111180981 (PRKCG)
  09159 Environmental adaptation
   04713 Circadian entrainment
    111180981 (PRKCG)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    111180981 (PRKCG)
   05206 MicroRNAs in cancer
    111180981 (PRKCG)
   05205 Proteoglycans in cancer
    111180981 (PRKCG)
   05231 Choline metabolism in cancer
    111180981 (PRKCG)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    111180981 (PRKCG)
   05214 Glioma
    111180981 (PRKCG)
   05223 Non-small cell lung cancer
    111180981 (PRKCG)
  09164 Neurodegenerative disease
   05017 Spinocerebellar ataxia
    111180981 (PRKCG)
   05022 Pathways of neurodegeneration - multiple diseases
    111180981 (PRKCG)
  09165 Substance dependence
   05031 Amphetamine addiction
    111180981 (PRKCG)
   05032 Morphine addiction
    111180981 (PRKCG)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    111180981 (PRKCG)
   05161 Hepatitis B
    111180981 (PRKCG)
   05171 Coronavirus disease - COVID-19
    111180981 (PRKCG)
   05163 Human cytomegalovirus infection
    111180981 (PRKCG)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    111180981 (PRKCG)
   05143 African trypanosomiasis
    111180981 (PRKCG)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    111180981 (PRKCG)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:dle01001]
    111180981 (PRKCG)
Enzymes [BR:dle01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.13  protein kinase C
     111180981 (PRKCG)
Protein kinases [BR:dle01001]
 Serine/threonine kinases: AGC group
  PKC family [OT]
   111180981 (PRKCG)
SSDB
Motif
Pfam: Pkinase C1_1 PK_Tyr_Ser-Thr C2 Pkinase_C Kinase-like
Other DBs
NCBI-GeneID: 111180981
NCBI-ProteinID: XP_022441643
UniProt: A0A2Y9PG78
LinkDB
Position
Unknown
AA seq 646 aa
MAGLGPGGGDSEGGPRPLFCRKGALRQKVVHEVKSHKFTARFFKQPTFCSHCTDFIWGIG
KQGLQCQVCSFVVHRRCHEFVTFECPGAGKGPQTDDPRNKHKFRLHSYSSPTFCDHCGSL
LYGLVHQGMKCSCCEMNVHRRCVRSVPSLCGVDHTERRGRLQLEIRAPTSDEIHVTVGEA
RNLIPMDPNGLSDPYVKLKLIPDPRNLTKQKTRTVKATLNPVWNETFVFNLKPGDVERRL
SVEVWDWDRTSRNDFMGAMSFGVSELLKVPVDGWYKLLNQEEGEYYNVPVADADNCSLLQ
KFEACNYPLELYEVMLAERRGSDELYAIKILKKDVIVQDDDVDCTLVEKRVLALGGRGPG
GRPHFLTQLHSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEIAIGLFFL
HNQGIIYRDLKLDNVMLDAEGHIKITDFGMCKENVFPGTTTRTFCGTPDYIAPEIIAYQP
YGKSVDWWSFGVLLYEMLAGQPPFDGEDEEELFQSIMEQTVTYPKSLSREAVAICKGFLT
KHPAKRLGSGPDGEPTIRAHGFFRWIDWERLERLEIAPPFRPRPCGRSGENFDKFFTRAA
PALTPPDRLVLASIDQTEFQGFTYVNPDFMHPDARSPISPAPVPVM
NT seq 1941 nt   +upstreamnt  +downstreamnt
atggcaggcctgggccccggcggaggcgattcagaggggggaccccggcccctgttttgc
agaaagggggctctgaggcagaaggtggtccacgaagtcaagagccacaagttcaccgct
cgcttcttcaagcagccaaccttctgcagccactgcactgacttcatatgggggattgga
aaacagggcctgcaatgtcaagtctgcagctttgtggttcatcgacgatgccacgaattt
gtgaccttcgagtgtccaggcgctgggaagggcccccagacagacgatccccggaacaag
cacaagttccgtctgcacagctacagcagccccaccttctgcgaccactgtggctccctc
ctttacgggctggtgcaccagggcatgaagtgctcctgctgcgagatgaacgtgcaccgg
cgctgtgtgcgcagcgtgccctctctgtgcggtgtggaccacacggagcgccgcggccgc
ctgcagctggaaatccgagctcccacttcggatgagatccacgtcacggttggcgaggcc
cgtaacctcatcccaatggaccccaatggtctgtctgatccctatgtgaaactgaagctc
atcccagatcctcggaatttgacaaaacagaagacccggacggtgaaagccacgctaaac
cctgtgtggaacgagacctttgtgttcaacctgaagccgggggacgtggagcgccggctc
agcgtggaggtgtgggactgggaccggacttcccgcaacgacttcatgggtgccatgtcc
tttggcgtctcggagctgctcaaggttcccgtggacggctggtacaagttactgaaccag
gaggagggcgaatattacaatgtgccagtggctgatgctgacaactgcagcctcctccag
aagtttgaggcctgtaactaccccctggaactgtacgaggtgatgctggccgagcgcagg
ggctccgatgagctctatgccatcaagatcctgaagaaagacgtgattgtccaggatgac
gacgtggactgcaccctggtggagaaacgcgtgttagccctggggggtcgaggccccgga
ggccggccccactttctcacccagcttcactccactttccagaccccggatcgcctgtat
tttgtgatggagtacgtcactgggggcgacttgatgtaccacattcagcagctgggcaag
tttaaggagccccatgcagcgttctacgcagcagaaatcgccatcggcctcttcttcctt
cacaatcagggcatcatctatcgggacctgaaactggacaacgtgatgctggatgctgaa
ggacacatcaaaatcaccgacttcggcatgtgtaaggagaacgtcttccccgggaccaca
actcgcaccttctgtgggaccccagactacatagcccccgagatcattgcctaccagccc
tatgggaagtctgtcgactggtggtcctttggggtcctgctgtatgagatgctggcgggg
cagcccccatttgatggggaagacgaggaggaactgttccagtccatcatggaacaaact
gtcacctacccgaagtcgctttcccgggaagctgtggccatctgcaaggggttcctaacc
aagcacccagcaaagcgcctgggctcggggccagatggagaacccaccatccgagctcat
ggctttttccgttggatcgactgggaacggctggaacgattagagatcgcgcctcctttc
agaccccgcccgtgtggccgcagcggcgagaacttcgacaagttcttcacgcgggcggcg
ccagcgttgactcccccagaccgcctagttctggccagcatcgaccaaaccgaattccaa
ggcttcacctatgtcaacccggatttcatgcacccggatgcccgcagccccatcagccca
gcacctgtgccagtcatgtaa

KEGG   Delphinapterus leucas (beluga whale): 111182232
Entry
111182232         CDS       T05885                                 

Gene name
PRKCB
Definition
(RefSeq) protein kinase C beta type isoform X1
  KO
K19662  classical protein kinase C beta type [EC:2.7.11.13]
Organism
dle  Delphinapterus leucas (beluga whale)
Pathway
dle01521  EGFR tyrosine kinase inhibitor resistance
dle04010  MAPK signaling pathway
dle04012  ErbB signaling pathway
dle04014  Ras signaling pathway
dle04015  Rap1 signaling pathway
dle04020  Calcium signaling pathway
dle04062  Chemokine signaling pathway
dle04064  NF-kappa B signaling pathway
dle04066  HIF-1 signaling pathway
dle04070  Phosphatidylinositol signaling system
dle04071  Sphingolipid signaling pathway
dle04150  mTOR signaling pathway
dle04270  Vascular smooth muscle contraction
dle04310  Wnt signaling pathway
dle04370  VEGF signaling pathway
dle04510  Focal adhesion
dle04540  Gap junction
dle04613  Neutrophil extracellular trap formation
dle04650  Natural killer cell mediated cytotoxicity
dle04662  B cell receptor signaling pathway
dle04666  Fc gamma R-mediated phagocytosis
dle04670  Leukocyte transendothelial migration
dle04713  Circadian entrainment
dle04720  Long-term potentiation
dle04723  Retrograde endocannabinoid signaling
dle04724  Glutamatergic synapse
dle04725  Cholinergic synapse
dle04726  Serotonergic synapse
dle04727  GABAergic synapse
dle04728  Dopaminergic synapse
dle04730  Long-term depression
dle04750  Inflammatory mediator regulation of TRP channels
dle04911  Insulin secretion
dle04912  GnRH signaling pathway
dle04916  Melanogenesis
dle04918  Thyroid hormone synthesis
dle04919  Thyroid hormone signaling pathway
dle04921  Oxytocin signaling pathway
dle04925  Aldosterone synthesis and secretion
dle04928  Parathyroid hormone synthesis, secretion and action
dle04929  GnRH secretion
dle04931  Insulin resistance
dle04933  AGE-RAGE signaling pathway in diabetic complications
dle04935  Growth hormone synthesis, secretion and action
dle04960  Aldosterone-regulated sodium reabsorption
dle04961  Endocrine and other factor-regulated calcium reabsorption
dle04970  Salivary secretion
dle04971  Gastric acid secretion
dle04972  Pancreatic secretion
dle04973  Carbohydrate digestion and absorption
dle05017  Spinocerebellar ataxia
dle05022  Pathways of neurodegeneration - multiple diseases
dle05031  Amphetamine addiction
dle05032  Morphine addiction
dle05140  Leishmaniasis
dle05143  African trypanosomiasis
dle05146  Amoebiasis
dle05161  Hepatitis B
dle05163  Human cytomegalovirus infection
dle05164  Influenza A
dle05170  Human immunodeficiency virus 1 infection
dle05171  Coronavirus disease - COVID-19
dle05200  Pathways in cancer
dle05205  Proteoglycans in cancer
dle05206  MicroRNAs in cancer
dle05214  Glioma
dle05223  Non-small cell lung cancer
dle05225  Hepatocellular carcinoma
dle05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:dle00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    111182232 (PRKCB)
   04012 ErbB signaling pathway
    111182232 (PRKCB)
   04014 Ras signaling pathway
    111182232 (PRKCB)
   04015 Rap1 signaling pathway
    111182232 (PRKCB)
   04310 Wnt signaling pathway
    111182232 (PRKCB)
   04370 VEGF signaling pathway
    111182232 (PRKCB)
   04064 NF-kappa B signaling pathway
    111182232 (PRKCB)
   04066 HIF-1 signaling pathway
    111182232 (PRKCB)
   04020 Calcium signaling pathway
    111182232 (PRKCB)
   04070 Phosphatidylinositol signaling system
    111182232 (PRKCB)
   04071 Sphingolipid signaling pathway
    111182232 (PRKCB)
   04150 mTOR signaling pathway
    111182232 (PRKCB)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    111182232 (PRKCB)
   04540 Gap junction
    111182232 (PRKCB)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    111182232 (PRKCB)
   04650 Natural killer cell mediated cytotoxicity
    111182232 (PRKCB)
   04662 B cell receptor signaling pathway
    111182232 (PRKCB)
   04666 Fc gamma R-mediated phagocytosis
    111182232 (PRKCB)
   04670 Leukocyte transendothelial migration
    111182232 (PRKCB)
   04062 Chemokine signaling pathway
    111182232 (PRKCB)
  09152 Endocrine system
   04911 Insulin secretion
    111182232 (PRKCB)
   04929 GnRH secretion
    111182232 (PRKCB)
   04912 GnRH signaling pathway
    111182232 (PRKCB)
   04921 Oxytocin signaling pathway
    111182232 (PRKCB)
   04935 Growth hormone synthesis, secretion and action
    111182232 (PRKCB)
   04918 Thyroid hormone synthesis
    111182232 (PRKCB)
   04919 Thyroid hormone signaling pathway
    111182232 (PRKCB)
   04928 Parathyroid hormone synthesis, secretion and action
    111182232 (PRKCB)
   04916 Melanogenesis
    111182232 (PRKCB)
   04925 Aldosterone synthesis and secretion
    111182232 (PRKCB)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    111182232 (PRKCB)
  09154 Digestive system
   04970 Salivary secretion
    111182232 (PRKCB)
   04971 Gastric acid secretion
    111182232 (PRKCB)
   04972 Pancreatic secretion
    111182232 (PRKCB)
   04973 Carbohydrate digestion and absorption
    111182232 (PRKCB)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    111182232 (PRKCB)
   04961 Endocrine and other factor-regulated calcium reabsorption
    111182232 (PRKCB)
  09156 Nervous system
   04724 Glutamatergic synapse
    111182232 (PRKCB)
   04727 GABAergic synapse
    111182232 (PRKCB)
   04725 Cholinergic synapse
    111182232 (PRKCB)
   04728 Dopaminergic synapse
    111182232 (PRKCB)
   04726 Serotonergic synapse
    111182232 (PRKCB)
   04720 Long-term potentiation
    111182232 (PRKCB)
   04730 Long-term depression
    111182232 (PRKCB)
   04723 Retrograde endocannabinoid signaling
    111182232 (PRKCB)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    111182232 (PRKCB)
  09159 Environmental adaptation
   04713 Circadian entrainment
    111182232 (PRKCB)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    111182232 (PRKCB)
   05206 MicroRNAs in cancer
    111182232 (PRKCB)
   05205 Proteoglycans in cancer
    111182232 (PRKCB)
   05231 Choline metabolism in cancer
    111182232 (PRKCB)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    111182232 (PRKCB)
   05214 Glioma
    111182232 (PRKCB)
   05223 Non-small cell lung cancer
    111182232 (PRKCB)
  09164 Neurodegenerative disease
   05017 Spinocerebellar ataxia
    111182232 (PRKCB)
   05022 Pathways of neurodegeneration - multiple diseases
    111182232 (PRKCB)
  09165 Substance dependence
   05031 Amphetamine addiction
    111182232 (PRKCB)
   05032 Morphine addiction
    111182232 (PRKCB)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    111182232 (PRKCB)
   04933 AGE-RAGE signaling pathway in diabetic complications
    111182232 (PRKCB)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    111182232 (PRKCB)
   05161 Hepatitis B
    111182232 (PRKCB)
   05171 Coronavirus disease - COVID-19
    111182232 (PRKCB)
   05164 Influenza A
    111182232 (PRKCB)
   05163 Human cytomegalovirus infection
    111182232 (PRKCB)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    111182232 (PRKCB)
   05140 Leishmaniasis
    111182232 (PRKCB)
   05143 African trypanosomiasis
    111182232 (PRKCB)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    111182232 (PRKCB)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:dle01001]
    111182232 (PRKCB)
Enzymes [BR:dle01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.13  protein kinase C
     111182232 (PRKCB)
Protein kinases [BR:dle01001]
 Serine/threonine kinases: AGC group
  PKC family [OT]
   111182232 (PRKCB)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr C1_1 C2 C1_2 Kinase-like CEP76-C2 APH
Other DBs
NCBI-GeneID: 111182232
NCBI-ProteinID: XP_022444221
UniProt: A0A2Y9PG08
LinkDB
Position
Unknown
AA seq 689 aa
MADPAAGPPPSEGEESTVRFARKGALRQKNVHEVKNHKFTARFFKQPTFCSHCTDFIWGF
GKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPASDDPRSKHKFKIHTYSSPTFCDHCGS
LLYGLIHQGMKCDTCMMNVHKRCVMNVPSLCGTDHTERRGRIYIQAHIEREVLIVVVRDA
KNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLKESDKDRRL
SVEIWDWDLTSRNDFMGSLSFGISELQKAGVDGWFKLLSQEEGEYFNVPVPPEGSEGNEE
LRQKFERAKINQGTKTPEEKTTNTISKFDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSE
RKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFVM
EYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHI
KIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAP
FEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFF
RYIDWEKLERKEIQPPYKPKALLTAQKDTRGSSRATGTEGWEASIMCQSTVVKILHFMLL
SFLIIKTTSLSVGEMLKTSTDFSPAIHQS
NT seq 2070 nt   +upstreamnt  +downstreamnt
atggctgacccggctgcggggccgccgccgagcgagggcgaggagagcacggtgcgcttc
gcccgcaaaggcgccctccggcagaagaacgtgcacgaggtgaagaaccacaaattcaca
gcccgcttcttcaagcagcccaccttctgcagccactgcaccgacttcatctggggcttc
gggaagcaaggattccagtgccaagtctgctgttttgtcgtgcacaagcggtgccatgag
tttgtcactttctcctgcccaggtgctgacaagggtccagcctccgatgacccccggagc
aaacacaagttcaagatccacacgtactccagccccacgttttgtgaccactgtgggtcg
ctgctgtatggactcatccaccaggggatgaaatgtgacacctgcatgatgaacgtccac
aagcgctgcgtgatgaacgtccccagcctctgtggcacagaccacacggagcgccgcggc
cgcatctacatccaggcccacatcgagagggaggtccttatcgttgtcgtaagagatgct
aaaaaccttgtacctatggaccctaatggcttgtctgatccttacgtgaaactgaaactg
attcctgatcccaagagtgagagcaagcagaagaccaaaaccatcaagtgctccctcaac
cccgagtggaacgagacatttagattccagctgaaagagtcggacaaagacagaagactg
tctgtagagatttgggattgggatctgaccagcaggaatgacttcatgggatctttgtcc
tttgggatttctgaactgcagaaagctggtgttgacggctggtttaagttacttagccag
gaagaaggcgagtacttcaacgtacctgtgccaccggaaggcagtgagggcaatgaggaa
ctgcggcagaaatttgagagggccaagatcaatcaggggaccaagactcctgaagaaaag
acgactaacaccatatccaaatttgacaacaacgggaacagggaccggatgaaactgacc
gattttaacttcctgatggtgcttggaaaaggcagctttggcaaggtcatgctctcagag
cggaagggcacagatgagctgtacgccgtgaagatcctgaagaaggatgtggtgattcaa
gacgatgacgtggaatgcacgatggtagagaagcgggtgctggccctgcccgggaagcca
cccttcctgacccagctgcattcctgcttccagaccatggaccgcctgtactttgtgatg
gagtatgtgaatggtggcgacctcatgtaccacatccaacaagtgggccggttcaaggaa
cctcacgctgtattttatgctgcggaaattgccattggtctgttcttcttacagagcaag
ggcatcatttaccgagacctgaaacttgacaatgtgatgctggattctgagggtcacatc
aagatcgctgatttcggcatgtgtaaggaaaacatctgggacggagtgacaaccaagacc
ttctgtggcactccagactacatcgcccctgagataattgcttatcagccctatgggaag
tccgtggattggtgggcattcggagtcctgctgtatgagatgttggctgggcaggcaccc
tttgaaggggaggatgaagatgaactcttccagtctatcatggaacacaacgtggcttat
ccaaagtccatgtccaaggaagctgtggccatctgcaaagggctgatgaccaaacacccg
ggcaaacgtctgggttgtggacctgaaggtgaacgtgacattaaagagcatgcgtttttc
cggtatattgactgggagaaacttgaacgcaaagagattcaacccccgtataagccgaaa
gccctcctgactgcccagaaggataccagaggcagctcacgagctacaggaactgaaggt
tgggaggccagcatcatgtgccaatcaacggtcgtgaaaattttgcattttatgttgctc
tcatttctgatcatcaaaacaacctctctgagtgtgggcgaaatgctgaaaacttcgacc
gatttttcacccgccatccaccagtcctaa

KEGG   Delphinapterus leucas (beluga whale): 111182917
Entry
111182917         CDS       T05885                                 

Gene name
PRKCA
Definition
(RefSeq) protein kinase C alpha type isoform X1
  KO
K02677  classical protein kinase C alpha type [EC:2.7.11.13]
Organism
dle  Delphinapterus leucas (beluga whale)
Pathway
dle01521  EGFR tyrosine kinase inhibitor resistance
dle04010  MAPK signaling pathway
dle04012  ErbB signaling pathway
dle04014  Ras signaling pathway
dle04015  Rap1 signaling pathway
dle04020  Calcium signaling pathway
dle04066  HIF-1 signaling pathway
dle04070  Phosphatidylinositol signaling system
dle04071  Sphingolipid signaling pathway
dle04072  Phospholipase D signaling pathway
dle04150  mTOR signaling pathway
dle04151  PI3K-Akt signaling pathway
dle04261  Adrenergic signaling in cardiomyocytes
dle04270  Vascular smooth muscle contraction
dle04310  Wnt signaling pathway
dle04360  Axon guidance
dle04370  VEGF signaling pathway
dle04510  Focal adhesion
dle04540  Gap junction
dle04613  Neutrophil extracellular trap formation
dle04650  Natural killer cell mediated cytotoxicity
dle04664  Fc epsilon RI signaling pathway
dle04666  Fc gamma R-mediated phagocytosis
dle04670  Leukocyte transendothelial migration
dle04713  Circadian entrainment
dle04720  Long-term potentiation
dle04723  Retrograde endocannabinoid signaling
dle04724  Glutamatergic synapse
dle04725  Cholinergic synapse
dle04726  Serotonergic synapse
dle04727  GABAergic synapse
dle04728  Dopaminergic synapse
dle04730  Long-term depression
dle04750  Inflammatory mediator regulation of TRP channels
dle04911  Insulin secretion
dle04912  GnRH signaling pathway
dle04916  Melanogenesis
dle04918  Thyroid hormone synthesis
dle04919  Thyroid hormone signaling pathway
dle04921  Oxytocin signaling pathway
dle04925  Aldosterone synthesis and secretion
dle04926  Relaxin signaling pathway
dle04928  Parathyroid hormone synthesis, secretion and action
dle04929  GnRH secretion
dle04933  AGE-RAGE signaling pathway in diabetic complications
dle04935  Growth hormone synthesis, secretion and action
dle04960  Aldosterone-regulated sodium reabsorption
dle04961  Endocrine and other factor-regulated calcium reabsorption
dle04970  Salivary secretion
dle04971  Gastric acid secretion
dle04972  Pancreatic secretion
dle05017  Spinocerebellar ataxia
dle05022  Pathways of neurodegeneration - multiple diseases
dle05031  Amphetamine addiction
dle05032  Morphine addiction
dle05143  African trypanosomiasis
dle05146  Amoebiasis
dle05161  Hepatitis B
dle05163  Human cytomegalovirus infection
dle05164  Influenza A
dle05170  Human immunodeficiency virus 1 infection
dle05171  Coronavirus disease - COVID-19
dle05200  Pathways in cancer
dle05205  Proteoglycans in cancer
dle05206  MicroRNAs in cancer
dle05214  Glioma
dle05223  Non-small cell lung cancer
dle05225  Hepatocellular carcinoma
dle05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:dle00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    111182917 (PRKCA)
   04012 ErbB signaling pathway
    111182917 (PRKCA)
   04014 Ras signaling pathway
    111182917 (PRKCA)
   04015 Rap1 signaling pathway
    111182917 (PRKCA)
   04310 Wnt signaling pathway
    111182917 (PRKCA)
   04370 VEGF signaling pathway
    111182917 (PRKCA)
   04066 HIF-1 signaling pathway
    111182917 (PRKCA)
   04020 Calcium signaling pathway
    111182917 (PRKCA)
   04070 Phosphatidylinositol signaling system
    111182917 (PRKCA)
   04072 Phospholipase D signaling pathway
    111182917 (PRKCA)
   04071 Sphingolipid signaling pathway
    111182917 (PRKCA)
   04151 PI3K-Akt signaling pathway
    111182917 (PRKCA)
   04150 mTOR signaling pathway
    111182917 (PRKCA)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    111182917 (PRKCA)
   04540 Gap junction
    111182917 (PRKCA)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    111182917 (PRKCA)
   04650 Natural killer cell mediated cytotoxicity
    111182917 (PRKCA)
   04664 Fc epsilon RI signaling pathway
    111182917 (PRKCA)
   04666 Fc gamma R-mediated phagocytosis
    111182917 (PRKCA)
   04670 Leukocyte transendothelial migration
    111182917 (PRKCA)
  09152 Endocrine system
   04911 Insulin secretion
    111182917 (PRKCA)
   04929 GnRH secretion
    111182917 (PRKCA)
   04912 GnRH signaling pathway
    111182917 (PRKCA)
   04921 Oxytocin signaling pathway
    111182917 (PRKCA)
   04926 Relaxin signaling pathway
    111182917 (PRKCA)
   04935 Growth hormone synthesis, secretion and action
    111182917 (PRKCA)
   04918 Thyroid hormone synthesis
    111182917 (PRKCA)
   04919 Thyroid hormone signaling pathway
    111182917 (PRKCA)
   04928 Parathyroid hormone synthesis, secretion and action
    111182917 (PRKCA)
   04916 Melanogenesis
    111182917 (PRKCA)
   04925 Aldosterone synthesis and secretion
    111182917 (PRKCA)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    111182917 (PRKCA)
   04270 Vascular smooth muscle contraction
    111182917 (PRKCA)
  09154 Digestive system
   04970 Salivary secretion
    111182917 (PRKCA)
   04971 Gastric acid secretion
    111182917 (PRKCA)
   04972 Pancreatic secretion
    111182917 (PRKCA)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    111182917 (PRKCA)
   04961 Endocrine and other factor-regulated calcium reabsorption
    111182917 (PRKCA)
  09156 Nervous system
   04724 Glutamatergic synapse
    111182917 (PRKCA)
   04727 GABAergic synapse
    111182917 (PRKCA)
   04725 Cholinergic synapse
    111182917 (PRKCA)
   04728 Dopaminergic synapse
    111182917 (PRKCA)
   04726 Serotonergic synapse
    111182917 (PRKCA)
   04720 Long-term potentiation
    111182917 (PRKCA)
   04730 Long-term depression
    111182917 (PRKCA)
   04723 Retrograde endocannabinoid signaling
    111182917 (PRKCA)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    111182917 (PRKCA)
  09158 Development and regeneration
   04360 Axon guidance
    111182917 (PRKCA)
  09159 Environmental adaptation
   04713 Circadian entrainment
    111182917 (PRKCA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    111182917 (PRKCA)
   05206 MicroRNAs in cancer
    111182917 (PRKCA)
   05205 Proteoglycans in cancer
    111182917 (PRKCA)
   05231 Choline metabolism in cancer
    111182917 (PRKCA)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    111182917 (PRKCA)
   05214 Glioma
    111182917 (PRKCA)
   05223 Non-small cell lung cancer
    111182917 (PRKCA)
  09164 Neurodegenerative disease
   05017 Spinocerebellar ataxia
    111182917 (PRKCA)
   05022 Pathways of neurodegeneration - multiple diseases
    111182917 (PRKCA)
  09165 Substance dependence
   05031 Amphetamine addiction
    111182917 (PRKCA)
   05032 Morphine addiction
    111182917 (PRKCA)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    111182917 (PRKCA)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    111182917 (PRKCA)
   05161 Hepatitis B
    111182917 (PRKCA)
   05171 Coronavirus disease - COVID-19
    111182917 (PRKCA)
   05164 Influenza A
    111182917 (PRKCA)
   05163 Human cytomegalovirus infection
    111182917 (PRKCA)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    111182917 (PRKCA)
   05143 African trypanosomiasis
    111182917 (PRKCA)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    111182917 (PRKCA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:dle01001]
    111182917 (PRKCA)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:dle04131]
    111182917 (PRKCA)
Enzymes [BR:dle01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.13  protein kinase C
     111182917 (PRKCA)
Protein kinases [BR:dle01001]
 Serine/threonine kinases: AGC group
  PKC family [OT]
   111182917 (PRKCA)
Membrane trafficking [BR:dle04131]
 Endocytosis
  Lipid raft mediated endocytosis
   Caveolin-mediated endocytosis
    111182917 (PRKCA)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr C1_1 C2 Pkinase_C C1_2 APH
Other DBs
NCBI-GeneID: 111182917
NCBI-ProteinID: XP_022445555
UniProt: A0A2Y9PID1
LinkDB
Position
Unknown
AA seq 670 aa
MADVFPANDSAAPQDVANRFARKGALRQKNVHEVKDHRFIARFFKQPTFCSHCTDFIWGF
GKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGS
LLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVTEEKLHVTVRDA
KNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFKLKPSDKDRRL
SVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGEYYNVPIPEGDEEGNAE
LRQKFEKAKLGPAGNKVISPDRRQPSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKGTE
ELYAIKILKKDVVIQDDDVECTLVEKRVLALPDKPPFLTQLHSCFQTVDRLYFVMEYVNG
GDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADF
GMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGED
EDELFQSIMEHNVSYPKSLSREAVSICKGLMTKHPGKRLGCGPEGERDVREHTFFRRIDW
EKLENREVQPPFKPKVCGKGAENFDKFFTRGQPVLTPPDQLVIANIDQSDFEGFSYVNPQ
FVHPILQSTV
NT seq 2013 nt   +upstreamnt  +downstreamnt
atggctgacgtcttcccggccaacgactcggcggcgcctcaggacgtggccaaccgcttc
gcccgcaaaggggcgctaagacagaagaacgtgcacgaggtgaaggaccaccgcttcatc
gcccgcttcttcaagcagcccaccttctgcagccactgcaccgactttatctgggggttt
gggaaacaaggcttccagtgccaagtttgctgttttgtggttcacaagaggtgccatgaa
tttgttactttttcttgtccgggtgcagataaaggacctgacactgatgaccccaggagc
aagcacaaattcaagatccacacctacggaagccccaccttctgcgatcactgcgggtcg
ctgctgtacggactcatccatcaggggatgaagtgtgacacctgtgatatgaacgtgcac
aagcagtgcgtgataaacgtccccagcctctgcgggatggaccacacggagaagaggggc
cggatctacctgaaggccgaggtcaccgaggaaaagctccacgtcacagtacgagatgca
aaaaatctcatccctatggatccaaatgggctttcagatccttatgtgaagctgaagctt
attcctgaccccaagaacgaaagcaaacaaaaaaccaaaaccatccgttccacactgaac
ccccagtggaatgagtcctttacgttcaaattaaaaccttcagataaagatcgacgactg
tccgtagagatctgggactgggatcgaacaaccaggaacgacttcatggggtccctttcc
ttcggagtctcggagctgatgaagatgccggccagtggatggtacaagttgctgaaccaa
gaagagggtgagtactacaacgtgcccattccagaaggcgatgaggaaggcaacgcagag
ctgaggcagaagttcgagaaagccaagctcggccctgctggcaacaaagtcattagtcct
gacaggagacagccttccaacaacctcgacagagtgaaactcaccgacttcaacttcctc
atggtgctgggcaagggcagcttcgggaaggtgatgctggcggacaggaaggggacggag
gagctgtacgccatcaagatattgaagaaggacgtggtgatccaggacgacgatgtggag
tgcaccctggtggagaagcgggtgctggccctgccggacaagccgccgttcctgacgcag
ctgcactcctgcttccagacggtggatcggctgtacttcgtcatggaatacgtcaatggc
ggggacctcatgtaccacatccagcaagtaggaaaatttaaggaaccgcaagcagtgttc
tacgcagcagagatttccattgggttgttctttcttcataaaagaggcatcatttataga
gacctgaagttagataacgtcatgctggattcggaaggacatatcaagattgcggacttt
gggatgtgtaaggagcacatgatggacggggtgactaccaggaccttctgcgggaccccg
gattacatcgccccggagataatcgcttatcagccatatgggaaatccgtggactggtgg
gcctacggcgtcctgttatatgaaatgctggccgggcagcctccatttgacggcgaggat
gaagacgagctgtttcagtccatcatggagcacaacgtctcgtacccgaagtccttgtcc
agggaggccgtctccatctgcaaagggctgatgaccaaacaccctggcaagcggctgggc
tgcggacccgagggagagcgggacgtgcgggaacacaccttcttccggaggatcgactgg
gagaagctggagaacagggaggtccagccgcccttcaagcccaaagtgtgcggcaaagga
gcagaaaacttcgacaagttcttcacgcgagggcagcctgtcttaacgccacccgatcag
ctggtcatcgctaacatcgaccagtctgattttgaagggttctcatatgtcaacccccag
ttcgtgcaccccatcctacagagcacagtatga

DBGET integrated database retrieval system