Delphinapterus leucas (beluga whale): 111181448
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Entry
111181448 CDS
T05885
Symbol
TYMS
Name
(RefSeq) thymidylate synthase isoform X1
KO
K00560
thymidylate synthase [EC:
2.1.1.45
]
Organism
dle
Delphinapterus leucas (beluga whale)
Pathway
dle00240
Pyrimidine metabolism
dle00670
One carbon pool by folate
dle01100
Metabolic pathways
dle01232
Nucleotide metabolism
dle01523
Antifolate resistance
Module
dle_M00938
Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:
dle00001
]
09100 Metabolism
09104 Nucleotide metabolism
00240 Pyrimidine metabolism
111181448 (TYMS)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
111181448 (TYMS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
111181448 (TYMS)
Enzymes [BR:
dle01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.45 thymidylate synthase
111181448 (TYMS)
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SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Thymidylat_synt
Motif
Other DBs
NCBI-GeneID:
111181448
NCBI-ProteinID:
XP_022442502
UniProt:
A0A2Y9PGX3
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All DBs
Position
Unknown
AA seq
317 aa
AA seq
DB search
MPAAGSELPRPMSPPAAQEQGAESRPPPPPPHGELQYLGQIEHILRCGFRKDDRTGTGTL
SVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRD
FLDSLGFSTRAEGDLGPVYGFQWRHFGAEYKEMDSDYSDQGVDQLQKVIDTIKTNPDDRR
IILCAWNPKDLPLMALPPCHALCQFYVVNGELSCQLYQRSGDMGLGVPFNIASYALLTYM
IAHITGLKPGDFVHTLGDAHIYLNHIEPLKIQLQREPRAFPKLKILRKVEKIDDFKAEDF
QIEGYNPHPTIKMEMAV
NT seq
954 nt
NT seq
+upstream
nt +downstream
nt
atgcccgccgccggctccgagctgccgcgcccgatgtcgccgcctgccgcgcaggagcag
ggcgccgagtcgcggccaccgccgccgccgccgcacggggagctgcagtacttggggcag
atcgagcacatcctccgctgcggctttcggaaggatgaccgcacgggcaccggcaccctg
tcggtgttcggcatgcaggcgcgctacagcctgagagatgaatttcctctgctgacaacc
aaacgtgttttctggaagggtgttttggaggagttgctgtggtttatcaagggatccaca
aacgctaaggagctgtcttccaagggagtgaaaatctgggatgccaatgggtcccgagac
ttcttggacagcctgggattctccaccagagcagaaggggatttaggcccagtttatggc
tttcagtggaggcattttggggccgaatacaaagagatggattcagattattcagatcaa
ggagtagatcaactgcaaaaagtgattgacacaatcaaaaccaaccctgacgacagaaga
atcatcctgtgtgcttggaatccaaaagatctccctctcatggccctacccccgtgccat
gccctttgccagttctacgtggtgaacggtgagctgtcctgccagctgtaccagaggtca
ggagacatgggcctgggtgtgcccttcaacatcgccagctacgccctgctcacctacatg
atcgcacacataacgggcctgaagccaggtgactttgtacacactttgggagatgcacac
atttacctgaatcacattgagccgctgaaaattcagcttcagcgagaaccaagggctttc
cccaagctcaaaatccttcgaaaagttgagaaaattgatgacttcaaggctgaagacttt
cagattgaaggctacaatcctcacccaaccattaaaatggaaatggctgtttag
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