KEGG   Delphinapterus leucas (beluga whale): 111181448
Entry
111181448         CDS       T05885                                 
Symbol
TYMS
Name
(RefSeq) thymidylate synthase isoform X1
  KO
K00560  thymidylate synthase [EC:2.1.1.45]
Organism
dle  Delphinapterus leucas (beluga whale)
Pathway
dle00240  Pyrimidine metabolism
dle00670  One carbon pool by folate
dle01100  Metabolic pathways
dle01232  Nucleotide metabolism
dle01523  Antifolate resistance
Module
dle_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:dle00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    111181448 (TYMS)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    111181448 (TYMS)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    111181448 (TYMS)
Enzymes [BR:dle01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.45  thymidylate synthase
     111181448 (TYMS)
SSDB
Motif
Pfam: Thymidylat_synt
Other DBs
NCBI-GeneID: 111181448
NCBI-ProteinID: XP_022442502
UniProt: A0A2Y9PGX3
LinkDB
Position
Unknown
AA seq 317 aa
MPAAGSELPRPMSPPAAQEQGAESRPPPPPPHGELQYLGQIEHILRCGFRKDDRTGTGTL
SVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRD
FLDSLGFSTRAEGDLGPVYGFQWRHFGAEYKEMDSDYSDQGVDQLQKVIDTIKTNPDDRR
IILCAWNPKDLPLMALPPCHALCQFYVVNGELSCQLYQRSGDMGLGVPFNIASYALLTYM
IAHITGLKPGDFVHTLGDAHIYLNHIEPLKIQLQREPRAFPKLKILRKVEKIDDFKAEDF
QIEGYNPHPTIKMEMAV
NT seq 954 nt   +upstreamnt  +downstreamnt
atgcccgccgccggctccgagctgccgcgcccgatgtcgccgcctgccgcgcaggagcag
ggcgccgagtcgcggccaccgccgccgccgccgcacggggagctgcagtacttggggcag
atcgagcacatcctccgctgcggctttcggaaggatgaccgcacgggcaccggcaccctg
tcggtgttcggcatgcaggcgcgctacagcctgagagatgaatttcctctgctgacaacc
aaacgtgttttctggaagggtgttttggaggagttgctgtggtttatcaagggatccaca
aacgctaaggagctgtcttccaagggagtgaaaatctgggatgccaatgggtcccgagac
ttcttggacagcctgggattctccaccagagcagaaggggatttaggcccagtttatggc
tttcagtggaggcattttggggccgaatacaaagagatggattcagattattcagatcaa
ggagtagatcaactgcaaaaagtgattgacacaatcaaaaccaaccctgacgacagaaga
atcatcctgtgtgcttggaatccaaaagatctccctctcatggccctacccccgtgccat
gccctttgccagttctacgtggtgaacggtgagctgtcctgccagctgtaccagaggtca
ggagacatgggcctgggtgtgcccttcaacatcgccagctacgccctgctcacctacatg
atcgcacacataacgggcctgaagccaggtgactttgtacacactttgggagatgcacac
atttacctgaatcacattgagccgctgaaaattcagcttcagcgagaaccaagggctttc
cccaagctcaaaatccttcgaaaagttgagaaaattgatgacttcaaggctgaagacttt
cagattgaaggctacaatcctcacccaaccattaaaatggaaatggctgtttag

DBGET integrated database retrieval system