Delphinapterus leucas (beluga whale): 111182917
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Entry
111182917 CDS
T05885
Gene name
PRKCA
Definition
(RefSeq) protein kinase C alpha type isoform X1
KO
K02677
classical protein kinase C alpha type [EC:
2.7.11.13
]
Organism
dle
Delphinapterus leucas (beluga whale)
Pathway
dle01521
EGFR tyrosine kinase inhibitor resistance
dle04010
MAPK signaling pathway
dle04012
ErbB signaling pathway
dle04014
Ras signaling pathway
dle04015
Rap1 signaling pathway
dle04020
Calcium signaling pathway
dle04066
HIF-1 signaling pathway
dle04070
Phosphatidylinositol signaling system
dle04071
Sphingolipid signaling pathway
dle04072
Phospholipase D signaling pathway
dle04150
mTOR signaling pathway
dle04151
PI3K-Akt signaling pathway
dle04261
Adrenergic signaling in cardiomyocytes
dle04270
Vascular smooth muscle contraction
dle04310
Wnt signaling pathway
dle04360
Axon guidance
dle04370
VEGF signaling pathway
dle04510
Focal adhesion
dle04540
Gap junction
dle04650
Natural killer cell mediated cytotoxicity
dle04664
Fc epsilon RI signaling pathway
dle04666
Fc gamma R-mediated phagocytosis
dle04670
Leukocyte transendothelial migration
dle04713
Circadian entrainment
dle04720
Long-term potentiation
dle04723
Retrograde endocannabinoid signaling
dle04724
Glutamatergic synapse
dle04725
Cholinergic synapse
dle04726
Serotonergic synapse
dle04727
GABAergic synapse
dle04728
Dopaminergic synapse
dle04730
Long-term depression
dle04750
Inflammatory mediator regulation of TRP channels
dle04911
Insulin secretion
dle04912
GnRH signaling pathway
dle04916
Melanogenesis
dle04918
Thyroid hormone synthesis
dle04919
Thyroid hormone signaling pathway
dle04921
Oxytocin signaling pathway
dle04925
Aldosterone synthesis and secretion
dle04926
Relaxin signaling pathway
dle04928
Parathyroid hormone synthesis, secretion and action
dle04929
GnRH secretion
dle04933
AGE-RAGE signaling pathway in diabetic complications
dle04935
Growth hormone synthesis, secretion and action
dle04960
Aldosterone-regulated sodium reabsorption
dle04961
Endocrine and other factor-regulated calcium reabsorption
dle04970
Salivary secretion
dle04971
Gastric acid secretion
dle04972
Pancreatic secretion
dle05017
Spinocerebellar ataxia
dle05022
Pathways of neurodegeneration - multiple diseases
dle05031
Amphetamine addiction
dle05032
Morphine addiction
dle05143
African trypanosomiasis
dle05146
Amoebiasis
dle05161
Hepatitis B
dle05163
Human cytomegalovirus infection
dle05164
Influenza A
dle05170
Human immunodeficiency virus 1 infection
dle05171
Coronavirus disease - COVID-19
dle05200
Pathways in cancer
dle05205
Proteoglycans in cancer
dle05206
MicroRNAs in cancer
dle05214
Glioma
dle05223
Non-small cell lung cancer
dle05225
Hepatocellular carcinoma
dle05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
dle00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
111182917 (PRKCA)
04012 ErbB signaling pathway
111182917 (PRKCA)
04014 Ras signaling pathway
111182917 (PRKCA)
04015 Rap1 signaling pathway
111182917 (PRKCA)
04310 Wnt signaling pathway
111182917 (PRKCA)
04370 VEGF signaling pathway
111182917 (PRKCA)
04066 HIF-1 signaling pathway
111182917 (PRKCA)
04020 Calcium signaling pathway
111182917 (PRKCA)
04070 Phosphatidylinositol signaling system
111182917 (PRKCA)
04072 Phospholipase D signaling pathway
111182917 (PRKCA)
04071 Sphingolipid signaling pathway
111182917 (PRKCA)
04151 PI3K-Akt signaling pathway
111182917 (PRKCA)
04150 mTOR signaling pathway
111182917 (PRKCA)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
111182917 (PRKCA)
04540 Gap junction
111182917 (PRKCA)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
111182917 (PRKCA)
04664 Fc epsilon RI signaling pathway
111182917 (PRKCA)
04666 Fc gamma R-mediated phagocytosis
111182917 (PRKCA)
04670 Leukocyte transendothelial migration
111182917 (PRKCA)
09152 Endocrine system
04911 Insulin secretion
111182917 (PRKCA)
04929 GnRH secretion
111182917 (PRKCA)
04912 GnRH signaling pathway
111182917 (PRKCA)
04921 Oxytocin signaling pathway
111182917 (PRKCA)
04926 Relaxin signaling pathway
111182917 (PRKCA)
04935 Growth hormone synthesis, secretion and action
111182917 (PRKCA)
04918 Thyroid hormone synthesis
111182917 (PRKCA)
04919 Thyroid hormone signaling pathway
111182917 (PRKCA)
04928 Parathyroid hormone synthesis, secretion and action
111182917 (PRKCA)
04916 Melanogenesis
111182917 (PRKCA)
04925 Aldosterone synthesis and secretion
111182917 (PRKCA)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
111182917 (PRKCA)
04270 Vascular smooth muscle contraction
111182917 (PRKCA)
09154 Digestive system
04970 Salivary secretion
111182917 (PRKCA)
04971 Gastric acid secretion
111182917 (PRKCA)
04972 Pancreatic secretion
111182917 (PRKCA)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
111182917 (PRKCA)
04961 Endocrine and other factor-regulated calcium reabsorption
111182917 (PRKCA)
09156 Nervous system
04724 Glutamatergic synapse
111182917 (PRKCA)
04727 GABAergic synapse
111182917 (PRKCA)
04725 Cholinergic synapse
111182917 (PRKCA)
04728 Dopaminergic synapse
111182917 (PRKCA)
04726 Serotonergic synapse
111182917 (PRKCA)
04720 Long-term potentiation
111182917 (PRKCA)
04730 Long-term depression
111182917 (PRKCA)
04723 Retrograde endocannabinoid signaling
111182917 (PRKCA)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
111182917 (PRKCA)
09158 Development and regeneration
04360 Axon guidance
111182917 (PRKCA)
09159 Environmental adaptation
04713 Circadian entrainment
111182917 (PRKCA)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
111182917 (PRKCA)
05206 MicroRNAs in cancer
111182917 (PRKCA)
05205 Proteoglycans in cancer
111182917 (PRKCA)
05231 Choline metabolism in cancer
111182917 (PRKCA)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
111182917 (PRKCA)
05214 Glioma
111182917 (PRKCA)
05223 Non-small cell lung cancer
111182917 (PRKCA)
09164 Neurodegenerative disease
05017 Spinocerebellar ataxia
111182917 (PRKCA)
05022 Pathways of neurodegeneration - multiple diseases
111182917 (PRKCA)
09165 Substance dependence
05031 Amphetamine addiction
111182917 (PRKCA)
05032 Morphine addiction
111182917 (PRKCA)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
111182917 (PRKCA)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
111182917 (PRKCA)
05161 Hepatitis B
111182917 (PRKCA)
05171 Coronavirus disease - COVID-19
111182917 (PRKCA)
05164 Influenza A
111182917 (PRKCA)
05163 Human cytomegalovirus infection
111182917 (PRKCA)
09174 Infectious disease: parasitic
05146 Amoebiasis
111182917 (PRKCA)
05143 African trypanosomiasis
111182917 (PRKCA)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
111182917 (PRKCA)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
dle01001
]
111182917 (PRKCA)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
dle04131
]
111182917 (PRKCA)
Enzymes [BR:
dle01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.13 protein kinase C
111182917 (PRKCA)
Protein kinases [BR:
dle01001
]
Serine/threonine kinases: AGC group
PKC family [OT]
111182917 (PRKCA)
Membrane trafficking [BR:
dle04131
]
Endocytosis
Lipid raft mediated endocytosis
Caveolin-mediated endocytosis
111182917 (PRKCA)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
C1_1
C2
Pkinase_C
C1_2
APH
Motif
Other DBs
NCBI-GeneID:
111182917
NCBI-ProteinID:
XP_022445555
UniProt:
A0A2Y9PID1
LinkDB
All DBs
Position
Unknown
AA seq
670 aa
AA seq
DB search
MADVFPANDSAAPQDVANRFARKGALRQKNVHEVKDHRFIARFFKQPTFCSHCTDFIWGF
GKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGS
LLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVTEEKLHVTVRDA
KNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFKLKPSDKDRRL
SVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGEYYNVPIPEGDEEGNAE
LRQKFEKAKLGPAGNKVISPDRRQPSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKGTE
ELYAIKILKKDVVIQDDDVECTLVEKRVLALPDKPPFLTQLHSCFQTVDRLYFVMEYVNG
GDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADF
GMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGED
EDELFQSIMEHNVSYPKSLSREAVSICKGLMTKHPGKRLGCGPEGERDVREHTFFRRIDW
EKLENREVQPPFKPKVCGKGAENFDKFFTRGQPVLTPPDQLVIANIDQSDFEGFSYVNPQ
FVHPILQSTV
NT seq
2013 nt
NT seq
+upstream
nt +downstream
nt
atggctgacgtcttcccggccaacgactcggcggcgcctcaggacgtggccaaccgcttc
gcccgcaaaggggcgctaagacagaagaacgtgcacgaggtgaaggaccaccgcttcatc
gcccgcttcttcaagcagcccaccttctgcagccactgcaccgactttatctgggggttt
gggaaacaaggcttccagtgccaagtttgctgttttgtggttcacaagaggtgccatgaa
tttgttactttttcttgtccgggtgcagataaaggacctgacactgatgaccccaggagc
aagcacaaattcaagatccacacctacggaagccccaccttctgcgatcactgcgggtcg
ctgctgtacggactcatccatcaggggatgaagtgtgacacctgtgatatgaacgtgcac
aagcagtgcgtgataaacgtccccagcctctgcgggatggaccacacggagaagaggggc
cggatctacctgaaggccgaggtcaccgaggaaaagctccacgtcacagtacgagatgca
aaaaatctcatccctatggatccaaatgggctttcagatccttatgtgaagctgaagctt
attcctgaccccaagaacgaaagcaaacaaaaaaccaaaaccatccgttccacactgaac
ccccagtggaatgagtcctttacgttcaaattaaaaccttcagataaagatcgacgactg
tccgtagagatctgggactgggatcgaacaaccaggaacgacttcatggggtccctttcc
ttcggagtctcggagctgatgaagatgccggccagtggatggtacaagttgctgaaccaa
gaagagggtgagtactacaacgtgcccattccagaaggcgatgaggaaggcaacgcagag
ctgaggcagaagttcgagaaagccaagctcggccctgctggcaacaaagtcattagtcct
gacaggagacagccttccaacaacctcgacagagtgaaactcaccgacttcaacttcctc
atggtgctgggcaagggcagcttcgggaaggtgatgctggcggacaggaaggggacggag
gagctgtacgccatcaagatattgaagaaggacgtggtgatccaggacgacgatgtggag
tgcaccctggtggagaagcgggtgctggccctgccggacaagccgccgttcctgacgcag
ctgcactcctgcttccagacggtggatcggctgtacttcgtcatggaatacgtcaatggc
ggggacctcatgtaccacatccagcaagtaggaaaatttaaggaaccgcaagcagtgttc
tacgcagcagagatttccattgggttgttctttcttcataaaagaggcatcatttataga
gacctgaagttagataacgtcatgctggattcggaaggacatatcaagattgcggacttt
gggatgtgtaaggagcacatgatggacggggtgactaccaggaccttctgcgggaccccg
gattacatcgccccggagataatcgcttatcagccatatgggaaatccgtggactggtgg
gcctacggcgtcctgttatatgaaatgctggccgggcagcctccatttgacggcgaggat
gaagacgagctgtttcagtccatcatggagcacaacgtctcgtacccgaagtccttgtcc
agggaggccgtctccatctgcaaagggctgatgaccaaacaccctggcaagcggctgggc
tgcggacccgagggagagcgggacgtgcgggaacacaccttcttccggaggatcgactgg
gagaagctggagaacagggaggtccagccgcccttcaagcccaaagtgtgcggcaaagga
gcagaaaacttcgacaagttcttcacgcgagggcagcctgtcttaacgccacccgatcag
ctggtcatcgctaacatcgaccagtctgattttgaagggttctcatatgtcaacccccag
ttcgtgcaccccatcctacagagcacagtatga
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integrated database retrieval system