Delphinapterus leucas (beluga whale): 111184548
Help
Entry
111184548 CDS
T05885
Gene name
EGFR
Definition
(RefSeq) epidermal growth factor receptor isoform X1
KO
K04361
epidermal growth factor receptor [EC:
2.7.10.1
]
Organism
dle
Delphinapterus leucas (beluga whale)
Pathway
dle01521
EGFR tyrosine kinase inhibitor resistance
dle01522
Endocrine resistance
dle04010
MAPK signaling pathway
dle04012
ErbB signaling pathway
dle04014
Ras signaling pathway
dle04015
Rap1 signaling pathway
dle04020
Calcium signaling pathway
dle04066
HIF-1 signaling pathway
dle04068
FoxO signaling pathway
dle04072
Phospholipase D signaling pathway
dle04144
Endocytosis
dle04151
PI3K-Akt signaling pathway
dle04510
Focal adhesion
dle04520
Adherens junction
dle04540
Gap junction
dle04630
JAK-STAT signaling pathway
dle04810
Regulation of actin cytoskeleton
dle04912
GnRH signaling pathway
dle04915
Estrogen signaling pathway
dle04921
Oxytocin signaling pathway
dle04926
Relaxin signaling pathway
dle04928
Parathyroid hormone synthesis, secretion and action
dle04934
Cushing syndrome
dle05160
Hepatitis C
dle05163
Human cytomegalovirus infection
dle05165
Human papillomavirus infection
dle05171
Coronavirus disease - COVID-19
dle05200
Pathways in cancer
dle05205
Proteoglycans in cancer
dle05206
MicroRNAs in cancer
dle05210
Colorectal cancer
dle05212
Pancreatic cancer
dle05213
Endometrial cancer
dle05214
Glioma
dle05215
Prostate cancer
dle05218
Melanoma
dle05219
Bladder cancer
dle05223
Non-small cell lung cancer
dle05224
Breast cancer
dle05225
Hepatocellular carcinoma
dle05226
Gastric cancer
dle05230
Central carbon metabolism in cancer
dle05231
Choline metabolism in cancer
dle05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
dle00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
111184548 (EGFR)
04012 ErbB signaling pathway
111184548 (EGFR)
04014 Ras signaling pathway
111184548 (EGFR)
04015 Rap1 signaling pathway
111184548 (EGFR)
04630 JAK-STAT signaling pathway
111184548 (EGFR)
04066 HIF-1 signaling pathway
111184548 (EGFR)
04068 FoxO signaling pathway
111184548 (EGFR)
04020 Calcium signaling pathway
111184548 (EGFR)
04072 Phospholipase D signaling pathway
111184548 (EGFR)
04151 PI3K-Akt signaling pathway
111184548 (EGFR)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
111184548 (EGFR)
09144 Cellular community - eukaryotes
04510 Focal adhesion
111184548 (EGFR)
04520 Adherens junction
111184548 (EGFR)
04540 Gap junction
111184548 (EGFR)
09142 Cell motility
04810 Regulation of actin cytoskeleton
111184548 (EGFR)
09150 Organismal Systems
09152 Endocrine system
04912 GnRH signaling pathway
111184548 (EGFR)
04915 Estrogen signaling pathway
111184548 (EGFR)
04921 Oxytocin signaling pathway
111184548 (EGFR)
04926 Relaxin signaling pathway
111184548 (EGFR)
04928 Parathyroid hormone synthesis, secretion and action
111184548 (EGFR)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
111184548 (EGFR)
05206 MicroRNAs in cancer
111184548 (EGFR)
05205 Proteoglycans in cancer
111184548 (EGFR)
05230 Central carbon metabolism in cancer
111184548 (EGFR)
05231 Choline metabolism in cancer
111184548 (EGFR)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
111184548 (EGFR)
09162 Cancer: specific types
05210 Colorectal cancer
111184548 (EGFR)
05212 Pancreatic cancer
111184548 (EGFR)
05225 Hepatocellular carcinoma
111184548 (EGFR)
05226 Gastric cancer
111184548 (EGFR)
05214 Glioma
111184548 (EGFR)
05218 Melanoma
111184548 (EGFR)
05219 Bladder cancer
111184548 (EGFR)
05215 Prostate cancer
111184548 (EGFR)
05213 Endometrial cancer
111184548 (EGFR)
05224 Breast cancer
111184548 (EGFR)
05223 Non-small cell lung cancer
111184548 (EGFR)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
111184548 (EGFR)
09172 Infectious disease: viral
05160 Hepatitis C
111184548 (EGFR)
05171 Coronavirus disease - COVID-19
111184548 (EGFR)
05163 Human cytomegalovirus infection
111184548 (EGFR)
05165 Human papillomavirus infection
111184548 (EGFR)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
111184548 (EGFR)
01522 Endocrine resistance
111184548 (EGFR)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
dle01001
]
111184548 (EGFR)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
dle04147
]
111184548 (EGFR)
Enzymes [BR:
dle01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
111184548 (EGFR)
Protein kinases [BR:
dle01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
111184548 (EGFR)
Exosome [BR:
dle04147
]
Exosomal proteins
Exosomal proteins of colorectal cancer cells
111184548 (EGFR)
Exosomal proteins of pancreatic cancer cells
111184548 (EGFR)
Exosomal proteins of bladder cancer cells
111184548 (EGFR)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
APH
Kinase-like
Borrelia_P83
Kdo
Motif
Other DBs
NCBI-GeneID:
111184548
NCBI-ProteinID:
XP_022448878
UniProt:
A0A2Y9Q0F2
LinkDB
All DBs
Position
Unknown
AA seq
1209 aa
AA seq
DB search
MRRSEAGRAVLLALLAAHFQASPALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEV
VLGNLEITYMQSSYNLSFLKTIQEVAGYVLIALNTVEKIPLEKLQIIRGNVLYENTHALA
VLSNYGANKTGLRELPMRNLQEILQGAVRFSNNPILCNMDTVQWRDIVNTDFLSNMSIEF
QSQLSRCPKCDPVCLNGSCWGAGKENCQKLTKVICAQQCSGRCRGRSPSDCCHSQCAAGC
TGPRESDCLVCRRFRDGATCKDTCPPLMLYDPTTYEMKVNPLGKYSFGATCVRKCPRNYV
VTDHGSCVRACSSESQEVEEDGVRKCKKCDGPCGKVCNGIGIGEFKDTLSINATNIKHFR
NCTSISGDLHILPVAFKGDSFTRTPPLDPKELDILKTVKEITGFLLIQAWPANRTGLHAF
ENLEIIRGRTKQHGQFSLAVVGLDITSLGLRSLKEISDGDVIISGNRRLCYADTINWKKL
FGTSSQKTKITNNRSEKECKAMGHVCDPLCSSEGCWGPKPKDCMSCRNFSRGKECVEKCN
VLKGEPREFIENSECVQCHPECLPQAMNVTCTGHGPGSCVKCAHNIDGPHCVKTCPAGVT
GENSTLIWKFADASHVCHLCHASCAYGCAGPGSEGCAVSGPRIPSIATGMVGALLLALVL
ALGVGLFLRRRRIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETELKKVKVLGS
GAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGI
CLTSTVQLITQLMPFGCLLDYVREHKDNIGSQHLLNWCVQIAKGMNYLEDRRLVHRDLAA
RNVLVKTPQHIKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSY
GVTVWELMTFGSKPYDGIPASEISTVLEKGERLPQPPICTIDVYMIMVKCWMIDADSRPK
FRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRTLMDEEDMQDVVDADEYLIPQ
QGFFHSPASSRTPLLSSLSSTSNTPTVACGDRNGQSYPLQEDSFLQRYSSDPTGTLNEDS
IDDAFLPAPEYVNQSIPKRPAGSVQNPVYRNQPLNPAPGRDPHYQNSHSNAVDSPEYLNT
TLPACTNGVLDGPALWAQKGGHQISLDNPDYQQAFFPKEAKSNGIFKGSAAENAEYLRVA
PAGSDLTGA
NT seq
3630 nt
NT seq
+upstream
nt +downstream
nt
atgcgacgctccgaagcgggccgcgccgtgctcctggcgctgctggccgcgcacttccag
gcgagtccggcgctggaggagaagaaagtttgccaagggacaagtaacaagctcacccag
ttgggcacttttgaagaccactttctgagcctccagaggatgttcaataactgtgaggtg
gtccttgggaatttggaaattacctacatgcaaagtagttacaacctttctttcctaaag
accatccaggaggttgctggctatgtactcattgccctcaacacagtggagaagattcct
ttggaaaagctgcagatcatcagaggaaatgtgctctatgaaaacacccatgccttagcg
gtcttatccaactacggtgcaaataaaacgggactgagggagttgcccatgagaaactta
caggagatcctgcaaggcgccgtgcgattcagcaacaaccctatcctctgcaacatggac
accgtccagtggagggacatcgtcaacaccgactttctaagcaatatgtcgattgaattt
cagagccagctgagcagatgcccaaagtgtgatccagtctgtcttaatggaagctgctgg
ggtgcagggaaggagaactgccagaaactgaccaaagtcatctgtgcccagcagtgttcc
gggcgctgccgcggcaggtcccccagcgactgctgccacagccagtgtgccgccggctgc
acggggccacgggagagtgactgcctggtctgccgcaggttccgggacggagccacgtgc
aaggacacatgcccgccactcatgctgtacgaccccaccacctacgagatgaaagtcaac
ccgctggggaagtacagcttcggcgccacctgtgtcaggaagtgcccccgtaactacgtg
gtgacggaccacggctcgtgcgtccgcgcctgcagctctgagagccaggaggtggaggag
gacggcgtccgcaagtgtaaaaagtgcgacggaccttgtggcaaagtttgtaacggaata
ggaattggtgagtttaaagacacactttccataaatgctacaaatattaaacacttcaga
aattgcacctcgatcagtggagaccttcatatcctgccagtagcatttaagggtgattcc
ttcacacgtactccacctctggacccaaaggaactggacattctaaaaaccgtaaaggaa
ataacagggtttttgctgattcaggcctggcctgcaaacaggactggcctccatgctttt
gagaacctggaaatcatacgtggcaggacgaagcaacatggtcagttttctctggcggtt
gttggcctggatataacgtccttgggattacgctccctcaaggagataagtgatggagat
gtgatcatttcaggaaaccgaaggttgtgctacgcagatacaataaactggaaaaaactc
tttgggacctcaagtcagaaaaccaaaattacaaacaacaggagtgaaaaagagtgcaag
gccatgggccacgtctgtgacccgctgtgctcgtcagagggctgctggggcccaaaaccc
aaagactgcatgtcttgccgaaacttcagccgtggcaaggagtgtgtggagaagtgcaac
gttctaaagggagagcccagggagttcattgaaaactccgagtgcgtgcagtgccatccg
gaatgcctgcctcaggccatgaacgtgacctgcacgggacacggaccaggcagctgtgta
aagtgtgcccacaacatcgacggccctcactgcgtcaagacctgccctgctggagtcaca
ggagaaaacagcaccctgatctggaagtttgcagatgccagtcacgtgtgtcacctgtgc
cacgccagctgcgcctacggctgtgctgggccaggttctgaaggctgtgcagtgagtggg
cccaggattccgtccatcgccaccgggatggtgggcgccctgctgctggccctggtgctg
gccctgggggtcggcctctttctgcgcaggcgtcgcatcgtccgcaagcgcacgctgcgc
cggctgctgcaggagcgcgagcttgtcgagcctctgacgcccagcggagaagctcccaac
caagctctcttgaggatcttaaaggagacggaattaaaaaaggtcaaggtgctgggctcc
ggagcattcggcacggtgtacaagggactctggatcccagaaggcgagaaggttaaaatt
cctgtggctatcaaggaattaagagaagccacatctccaaaagccaacaaggaaattctt
gatgaagcctacgtgatggccagtgtggacaatccgcacgtgtgccgcctcctgggcatc
tgcctgacgtccacggtgcagctcatcacgcagctcatgcccttcggctgcctgctggac
tatgtccgcgagcacaaggacaacatcggctcccagcacctgctcaactggtgcgtgcag
atcgcaaagggcatgaactacctggaagaccggcgcctggtgcaccgagacctggcggcc
aggaatgtgctggtgaagacaccgcagcacatcaagatcacggatttcggcctggccaaa
ctgctcggcgccgaggagaaagaataccacgcggaggggggcaaggtgcctatcaagtgg
atggctttggaatcaattttacaccgaatttatacccaccagagtgacgtctggagctac
ggagtcaccgtttgggagttgatgacctttgggtccaagccttacgacgggatccccgcg
agtgagatctcaaccgtcctggagaagggagaacgcctgcctcagccgcccatctgcacc
atcgacgtctacatgatcatggtcaagtgctggatgattgatgcagacagtcgcccaaag
ttccgtgagttgatcattgaattctccaaaatggcccgagacccccagcgctaccttgtc
atccagggggacgagagaatgcatttgccaagccccacggactccaacttctaccgcacc
ctgatggacgaagaggacatgcaagatgttgtggatgcggacgagtacctcatcccccag
cagggcttcttccacagccccgccagctcccggacgcccctcctcagttctctgagctcc
accagcaacacgcccactgtggcttgcggtgatagaaacgggcagagctatcccctccag
gaagatagcttcttgcagcggtacagctcagaccccactggcaccttgaacgaggacagc
atagatgacgccttccttccagcgcccgaatacgtaaaccagtctattcccaaaaggccc
gcgggctctgtccagaaccccgtctatcgcaatcagcctctaaacccggctccaggcaga
gaccctcactaccagaattcccacagcaatgccgtggacagccctgagtatctcaacacc
acccttcccgcctgcaccaacggtgtgctcgacggccctgccctctgggcacagaagggc
ggtcaccaaattagcctggacaaccctgactaccagcaggccttctttcccaaggaagcc
aagtcaaatggcatctttaagggttctgccgctgaaaatgcagaatacctaagggtagca
ccagcgggcagcgaccttaccggggcctga
DBGET
integrated database retrieval system
