KEGG   Delphinapterus leucas (beluga whale): 111186135
Entry
111186135         CDS       T05885                                 

Gene name
EGF
Definition
(RefSeq) pro-epidermal growth factor
  KO
K04357  epidermal growth factor
Organism
dle  Delphinapterus leucas (beluga whale)
Pathway
dle01521  EGFR tyrosine kinase inhibitor resistance
dle04010  MAPK signaling pathway
dle04012  ErbB signaling pathway
dle04014  Ras signaling pathway
dle04015  Rap1 signaling pathway
dle04020  Calcium signaling pathway
dle04066  HIF-1 signaling pathway
dle04068  FoxO signaling pathway
dle04072  Phospholipase D signaling pathway
dle04151  PI3K-Akt signaling pathway
dle04510  Focal adhesion
dle04540  Gap junction
dle04630  JAK-STAT signaling pathway
dle04810  Regulation of actin cytoskeleton
dle05160  Hepatitis C
dle05165  Human papillomavirus infection
dle05200  Pathways in cancer
dle05210  Colorectal cancer
dle05212  Pancreatic cancer
dle05213  Endometrial cancer
dle05214  Glioma
dle05215  Prostate cancer
dle05218  Melanoma
dle05219  Bladder cancer
dle05223  Non-small cell lung cancer
dle05224  Breast cancer
dle05226  Gastric cancer
dle05231  Choline metabolism in cancer
dle05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:dle00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    111186135 (EGF)
   04012 ErbB signaling pathway
    111186135 (EGF)
   04014 Ras signaling pathway
    111186135 (EGF)
   04015 Rap1 signaling pathway
    111186135 (EGF)
   04630 JAK-STAT signaling pathway
    111186135 (EGF)
   04066 HIF-1 signaling pathway
    111186135 (EGF)
   04068 FoxO signaling pathway
    111186135 (EGF)
   04020 Calcium signaling pathway
    111186135 (EGF)
   04072 Phospholipase D signaling pathway
    111186135 (EGF)
   04151 PI3K-Akt signaling pathway
    111186135 (EGF)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    111186135 (EGF)
   04540 Gap junction
    111186135 (EGF)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    111186135 (EGF)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    111186135 (EGF)
   05231 Choline metabolism in cancer
    111186135 (EGF)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    111186135 (EGF)
  09162 Cancer: specific types
   05210 Colorectal cancer
    111186135 (EGF)
   05212 Pancreatic cancer
    111186135 (EGF)
   05226 Gastric cancer
    111186135 (EGF)
   05214 Glioma
    111186135 (EGF)
   05218 Melanoma
    111186135 (EGF)
   05219 Bladder cancer
    111186135 (EGF)
   05215 Prostate cancer
    111186135 (EGF)
   05213 Endometrial cancer
    111186135 (EGF)
   05224 Breast cancer
    111186135 (EGF)
   05223 Non-small cell lung cancer
    111186135 (EGF)
  09172 Infectious disease: viral
   05160 Hepatitis C
    111186135 (EGF)
   05165 Human papillomavirus infection
    111186135 (EGF)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    111186135 (EGF)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:dle04052]
    111186135 (EGF)
Cytokines and growth factors [BR:dle04052]
 Growth factors
  Growth factors (RTK binding)
   111186135 (EGF)
SSDB
Motif
Pfam: Ldl_recept_b FXa_inhibition cEGF EGF_CA EGF EGF_3 DUF5050 Plasmod_Pvs28 Tr-sialidase_C
Other DBs
NCBI-GeneID: 111186135
NCBI-ProteinID: XP_030615977
LinkDB
Position
Unknown
AA seq 1157 aa
MLLFLIILLPVVFKFSFVSLSARQRWSCPEGSPSGNGNSTCVGPAPFLIFSHGNRIFRID
LEGTNHEQLVADAGMSMIMDFHYNEERIYWVDLERQLLQRVFLNGTSQEKICEIEKNVSG
MAINWINEELIWSNQQEGIITVTDMKGNNSRVLLSALKYPANIAVDPVERFMFWSSEVAG
SLHRADLGGVEVKLLLETSEKITAVSLDVLEKRLFWIQYHRERSNSRICSCDYDGGSVHF
SQHHTQHNIFAMSLFGDRIFYSTWKKKTIWIANKYTGKNMVKINLSPSFVPGGIKVVHPL
VQPKAEGDPWVPDQKLCKLRKGNCRSSMCGQEPKSHVCMCAEGYALSQDGKNCEDVNECA
FWNHGCTLGCENIPGSYYCTCPVGFVLLPDGKRCHQLISCPSNVSECSHDCVLTSDGPIC
FCPEGSVLETDGKTCSGCSSPDNGGCSQLCTPLSPVSWECGCIPGYDLQLDKKSCTASGP
PPFLLFANSQDIRHMHFDGTDYGTLLSQQIGMVFALDHDPVENKIYFAHTALKWIERANM
DGSQRERLIEEEVGVPEGLAVDWIGRKFYWTDRRKSLIEGSDLNGKYREIIIKEDISQPR
GLAVHPMAKRLFWTEMGINPRIESSSLQGIGRLVIASSDLVWPSGITIDYLTDKLYWCDA
KQSVIEMSNLDGSKRQRLAQNDVGHPFAVAVFEDHLWFSDWAMPSVIRVNKRTGKNRVCL
RGSMLKPSSLVVVHPLAKPGADACLHQNGGCEHICEERFGTAQCLCREGFVKAPDGKTCL
ALNGHQILAGSGADLSNGVIPLDILPSSREMEDNITESQHMLVAEIMVSDGDDCSALGCS
TQAWCVSEGENVTCRCLKGFAGDGKLCSDIDECQMGISVCPPTSSKCVNTEGGHVCRCSE
GYQGDGIHCLDIDECQLGVHTCGENAACTNTEGNYTCTCAGNSSEPGRICPDSTPPSQPR
EDGRSPVRNIYPECPPSHDGYCLHGGVCMYVEAVDSYACNCVIGYVGERCQHRDLKWWEL
RHAGHGRQRSITAVAACVVVLLLLLLLGLCGAQKYRTQKLLSKNPRNPYEESSRDVSSTR
PVDEEAGMSSYPQPWFVVIEEHQNFSNGSQPVALKDGLVADVGQFSSLEPGSLRPTSWRK
EPQMYMGTEQGCCFIIQ
NT seq 3474 nt   +upstreamnt  +downstreamnt
atgctgctgttccttatcattctgttgccggtagtttttaaatttagttttgtgagcctc
tcagcacggcagcgctggagctgtcctgaaggctctccctcgggaaatgggaattctact
tgtgtgggtcctgcacccttcttaattttctcacatggaaacaggatctttaggattgac
ttggaaggaactaatcatgagcagttggtagcagatgccggcatgtccatgatcatggat
tttcattacaatgaagaaagaatctattgggtcgatctagaaagacaacttttgcaaaga
gtttttctgaatgggacaagccaagagaaaatatgcgagatagagaaaaatgtttcggga
atggcaataaattggatcaatgaagaacttatttggtcaaatcaacaggaaggaatcatt
acagtaacagatatgaaaggaaacaattcccgcgttctcttaagcgccttaaaatatcct
gcaaatatagcagttgatccagtagaaaggtttatgttttggtcttcagaggtggcgggc
agccttcacagagcagatcttggtggtgtggaagtgaagcttctgttagagacatcagag
aaaataacagctgtgtcattggatgtgcttgagaaacggctcttttggattcagtaccat
agagaaagaagcaattctcgtatttgttcctgtgattacgatggaggttccgtccatttt
agccaacatcacacacagcacaatatttttgcgatgtccctttttggtgatcgtattttc
tattcaacatggaaaaagaagacaatttggatagctaacaagtacactgggaagaatatg
gtcaaaattaacctcagtccatcatttgtacctggtggaattaaagtagtgcatccactc
gtacagcccaaggcagagggtgatccttgggtacctgatcagaaactctgcaaactgagg
aaaggtaactgcagaagcagcatgtgtgggcaagagcctaagtcccatgtgtgcatgtgt
gcagagggatatgctttaagccaagatggaaagaactgtgaagatgtcaacgagtgtgcc
ttttggaatcatggctgtactcttgggtgtgaaaacatccctggatcctattattgcaca
tgccctgtaggatttgttctgcttcctgatgggaaacggtgtcaccaattaatttcctgc
ccaagcaatgtgtctgaatgcagtcatgattgtgttctgacatcagacggtcccatatgt
ttctgtcctgaaggctcagtgcttgagacagatgggaaaacctgtagtggttgttcatct
cctgataatggtggatgtagccagctctgcacccctcttagcccagtatcctgggaatgt
ggctgcattccgggctatgacctacaactggacaaaaagagctgtacagcctcaggacca
ccaccgtttttgctgtttgccaattctcaagatattcgacacatgcattttgatggaaca
gattatggaaccctgctcagccagcagataggaatggtttttgccctagatcatgaccct
gtggagaataagatatactttgcccatacagccctaaagtggatagagagagcaaatatg
gatggttcccagcgagaaaggcttattgaggaagaagtaggtgtgccagaaggtcttgct
gtagactggattggccgtaaattctattggacagacagacggaaatctctcattgaaggg
agtgatttaaatgggaagtatcgtgaaataatcattaaggaggacatctctcagccacga
ggacttgctgttcatccaatggccaagagattattctggactgagatggggattaatcca
cgaattgaaagctcttcccttcaaggcattggccgactggttatagctagctcggatctg
gtctggcccagtggaataacaattgattacttaactgacaagttgtattggtgcgatgcc
aagcagtctgtgattgaaatgtccaatctggatggttcaaaacgccaaagacttgcccag
aacgatgtaggtcacccatttgctgtggctgtgtttgaggatcatttgtggttctctgat
tgggctatgccatcggtaataagggtgaacaagaggactggcaaaaatagggtatgtctc
cgaggcagcatgctgaagccctcatcactggttgtagttcatccattggcaaaaccagga
gcagatgcctgcttacatcaaaacggaggctgtgaacatatttgcgaagagaggtttgga
actgctcagtgtttgtgtcgtgaaggttttgtgaaagctccagatggaaaaacgtgtctg
gctctgaatggccatcagatattggcaggtagtggagcagatctgagtaatggagtaata
ccgttggacatcttacccagcagtagagagatggaagataatattacagaatctcagcat
atgctagtggctgaaatcatggtgtcagatggtgacgactgtagtgccttgggatgcagt
acacaggcttggtgtgtttcagagggagagaatgtcacgtgtcggtgtttgaaaggattt
gccggagatggaaaactgtgttctgatatagatgaatgtcagatgggtatttcagtttgc
cctcccacctcctccaagtgcgtcaatactgaaggtggccatgtctgccggtgctcagaa
ggctaccagggagatgggatccactgcctcgatattgatgagtgccaactgggtgtgcac
acctgtggggaaaatgccgcctgtacaaatacggagggaaactacacctgcacatgtgct
ggcaactcatctgaacctggacggatttgccctgactcgactccaccctctcaacccagg
gaggatggccgctctcctgtgagaaatatttaccccgaatgtcccccgtcccacgatggg
tactgcctccatggcggtgtgtgtatgtatgttgaagcggtcgacagctatgcctgcaac
tgtgtcattggctacgtcggggagcgatgtcagcaccgagacttgaagtggtgggaactg
cgccatgccggccatgggcggcagcggagcatcaccgctgtggctgcctgcgtggtggtg
ctgcttctgctgctgctcctggggctgtgcggggctcagaaatacaggactcagaagctg
ctatcgaaaaatccgaggaatccttatgaagagtcgagcagagatgtgagcagtaccagg
cctgtagatgaggaggctgggatgtcctcttacccccaaccttggtttgtggttatagag
gaacatcagaacttcagcaatgggagtcaacctgtagccctcaaggacggcctggtggca
gatgttggccagttttcttccctggagcctgggtcattgcgaccaacatcatggagaaag
gagccccagatgtatatgggcacagaacaaggatgctgtttcatcatccagtga

DBGET integrated database retrieval system