KEGG   Delphinapterus leucas (beluga whale): 111187768
Entry
111187768         CDS       T05885                                 

Gene name
GAB1
Definition
(RefSeq) GRB2-associated-binding protein 1 isoform X1
  KO
K09593  GRB2-associated-binding protein 1
Organism
dle  Delphinapterus leucas (beluga whale)
Pathway
dle01521  EGFR tyrosine kinase inhibitor resistance
dle04012  ErbB signaling pathway
dle04014  Ras signaling pathway
dle04072  Phospholipase D signaling pathway
dle04722  Neurotrophin signaling pathway
dle05100  Bacterial invasion of epithelial cells
dle05205  Proteoglycans in cancer
dle05211  Renal cell carcinoma
dle05225  Hepatocellular carcinoma
dle05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:dle00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    111187768 (GAB1)
   04014 Ras signaling pathway
    111187768 (GAB1)
   04072 Phospholipase D signaling pathway
    111187768 (GAB1)
 09150 Organismal Systems
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    111187768 (GAB1)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    111187768 (GAB1)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    111187768 (GAB1)
   05226 Gastric cancer
    111187768 (GAB1)
   05211 Renal cell carcinoma
    111187768 (GAB1)
  09171 Infectious disease: bacterial
   05100 Bacterial invasion of epithelial cells
    111187768 (GAB1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    111187768 (GAB1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04990 Domain-containing proteins not elsewhere classified [BR:dle04990]
    111187768 (GAB1)
Domain-containing proteins not elsewhere classified [BR:dle04990]
 Pleckstrin homology (PH) domain-containing proteins
  Grb-2 associated binder (Gab) family proteins
   111187768 (GAB1)
SSDB
Motif
Pfam: PH PH_11 PH_8 PH_9 PH_13
Other DBs
NCBI-GeneID: 111187768
NCBI-ProteinID: XP_022455441
UniProt: A0A2Y9QCZ2
LinkDB
Position
Unknown
AA seq 757 aa
MAPQVTPGEKVEALSLSSVLHWMLAAFPLPLPWVRSSFPIASSLVSLHRTSASKPSKAWK
RRWFVLRSGRLTGDPDVLEYYKNDHAKKPIRIIDLNLCQQVDAGLTFNKKEFENSYIFDI
NTIDRIFYLVADSEEEMNKWVRCICDICGFNPTEEDPVKPPGSSLQAPADLPLAINTAPP
STQVDASSAAPPPPYQLISLPPHLETLGIQEDPQDYLLLINCQSKKPEPTRTHADSAKST
PSETDCNDNVPSHKDPASSQSKHGVNGFFQQQMLYDSPPPRAASISVDSSLYNLPRSHSH
DVLPKVSPSSTEADGELYVFNTPSGTSSVEPQMRHVSISYDIPPTPGNTYQIPRTFPEGT
LGQTSKLDTIPDIPPPRPPKPHPAHDRSPVDTCSITRTASDTDSSYCIPTAGVPPSRSNT
ISTVDLNKLRKDASSQDCYDIPRTFPTDRSSSLEGFHNHFKIKNVLTVGSVSSEELDENY
VPMNPNSPPRQHSSSFTEPIQEANYVPMTPGTFDFSSFGMQVPPPAHMGFRSSPKTPPRR
PVPVADCEPPPVDRNLKPDRKGQSPKILRPKPHGLERTDSQTIGDFATRRKVKPAPLEIK
PLPEWEELQAPVRSPITRSFARDSSRFPMSPRPDSVHSTTSSSDSHDSEENYVPMNPNLS
SEDSNLFGSNSLDGGNSPMIKPKGDKQVEYLDLDLDSGKSTPPRKQKSSGSGSSVADERV
DYVVVDQQKTLALKSTREAWTDGRQSTESETPAKNVK
NT seq 2274 nt   +upstreamnt  +downstreamnt
atggctccgcaagtcacccccggagaaaaagttgaagcgttatccctctcctctgtcttg
cactggatgcttgctgcgttcccactgccgctaccgtgggtcagatcttcttttcccatt
gcgtcctcactggtctccctgcacagaacctcagcctccaaaccatccaaggcatggaag
aggagatggtttgtgttacgcagtggccgtttaactggagatccagatgtcttggaatat
tacaaaaatgatcatgccaagaagcctatccgcattattgatttaaatttatgtcagcaa
gttgatgctggattgacatttaacaaaaaagagtttgaaaacagctacatttttgatatc
aacaccattgaccggattttctacttggtagcagacagtgaagaggagatgaataagtgg
gttcgttgtatttgtgacatctgtgggtttaatcctacagaagaagatcctgtgaagcca
cctggcagctccttacaagcaccggctgatttaccactggcgataaatacagcaccacca
tccacccaggtggatgcctcctctgccgctccacctcctccatatcagctaattagcctt
ccaccacacctggaaacccttggcatccaggaggatcctcaagactacctcttgctaatc
aactgtcagagcaagaagcctgaacccaccagaacgcatgctgattctgcaaaatccacc
ccttcggagacagactgcaatgataacgtcccttctcataaagatcctgcttcctcccag
agcaaacatggagtgaatggctttttccagcagcagatgttgtatgactctccaccgcct
cgggctgcatccatttccgtagactccagcctttataacctgcccagaagtcactcccat
gacgtcttaccaaaggtgtctccttcaagtaccgaagccgacggagagctctatgttttt
aataccccatccgggacctcgagtgtagagcctcaaatgaggcatgtatctattagttat
gacattcctccaacacctggtaatacttatcagattccacgaacatttccagaaggaacc
ttggggcagacgtcaaagctagacactattccagatattcctccacctcggccaccgaaa
ccgcatccggctcatgaccgatctcctgtggacacgtgtagcatcacacgcacagcctct
gacactgacagtagttactgtatcccgacagcaggggtgccaccatcccgtagtaatacc
atttccactgtggatttgaacaaattgcgaaaagatgctagttctcaagactgctatgat
attccacgaacatttccaactgatagatctagttcacttgaaggcttccacaaccacttt
aaaatcaaaaacgtattgacagtggggagtgtatcaagcgaagaactggatgaaaattat
gtccccatgaatcccaactctcctccacgacaacattccagcagtttcacggaaccaatt
caggaagcaaattatgtgccaatgactccggggacatttgatttttcttcatttggaatg
caagtgcctcctcccgctcatatgggcttcaggtccagcccaaagacccctcctagaagg
ccagttcctgttgcagactgtgaaccaccccccgtggatcggaacctcaagccagacaga
aaaggtcaaagtcctaaaattttaagacccaaaccccatggtttagagcgaactgattca
caaaccataggtgactttgctacaagaagaaaggtcaagccagcacctttagaaataaaa
cctttgccagaatgggaagaattacaagccccagtaagatctcccatcactaggagtttt
gctcgagactcctccaggtttcccatgtctccccggccggattcagtgcacagcacgact
tcaagcagtgactcacatgacagtgaagagaattacgttcccatgaacccaaacctgtcc
agtgaagactcaaatctttttggcagtaatagtcttgatggaggaaacagcccaatgatc
aagcccaaaggagacaaacaagtggaatacctagatctagatttagattctgggaaatcc
acgccaccacgtaagcaaaagagcagtggctcaggcagcagtgtagctgacgagagagtg
gactatgtcgtggttgaccaacagaagaccctggctctgaagagcacccgtgaagcctgg
accgatgggagacagtccacagagtctgaaacgccagccaagaatgtgaagtga

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