Entry |
|
Name |
Sulindac (JP18/USP/INN); Clinoril (TN) |
Product |
|
Generic |
SULINDAC (A-S Medication Solutions), SULINDAC (Actavis Pharma), SULINDAC (Epic Pharma), SULINDAC (Lake Erie Medical DBA Quality Care Products LLC), SULINDAC (Major Pharmaceuticals), SULINDAC (PD-Rx Pharmaceuticals), SULINDAC (PD-Rx Pharmaceuticals), SULINDAC (PD-Rx Pharmaceuticals), SULINDAC (Proficient Rx LP), SULINDAC (PuraCap Laboratories LLC dba Blu Pharmaceuticals), SULINDAC (Sun Pharmaceutical Industries) |
Formula |
C20H17FO3S
|
Exact mass |
356.0882
|
Mol weight |
356.41
|
Structure |
|
Simcomp |
|
Class |
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01906 Anti-inflammatory drug, acetic acid derivatives
|
Remark |
|
Efficacy |
Analgesic, Anti-inflammatory, COX inhibitor |
Comment |
Acetic acid derivative
|
Target |
|
Pathway |
|
Interaction |
|
Structure map |
|
Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
M MUSCULO-SKELETAL SYSTEM
M01 ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
M01A ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
M01AB Acetic acid derivatives and related substances
M01AB02 Sulindac
D00120 Sulindac (JP18/USP/INN) <US>
USP drug classification [BR:br08302]
Analgesics
Nonsteroidal Anti-inflammatory Drugs
Sulindac
D00120 Sulindac (JP18/USP/INN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01906 Anti-inflammatory drug, acetic acid derivatives
D00120 Sulindac
Drug classes [BR:br08332]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
D00120 Sulindac
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases (EC1)
Prostaglandin synthase
PTGS1 (COX1)
D00120 Sulindac (JP18/USP/INN) <US>
PTGS2 (COX2)
D00120 Sulindac (JP18/USP/INN) <US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00120 Sulindac
|
Other DBs |
|
LinkDB |
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KCF data |
ATOM 25
1 C8y C 21.4726 -14.1927
2 C8y C 21.4726 -12.8437
3 C2y C 22.6354 -14.8905
4 C8x C 20.2632 -14.8905
5 C2y C 23.8449 -12.8437
6 C8x C 20.2632 -12.1460
7 C2y C 23.8449 -14.1927
8 C2b C 22.6354 -16.2394
9 C8x C 19.1003 -14.1927
10 C8y C 19.1003 -12.8437
11 C1a C 24.9378 -14.9605
12 C8y C 21.4726 -16.9371
13 X F 17.9374 -12.1460
14 C8x C 21.4726 -18.2860
15 C8x C 20.3097 -16.2394
16 C8x C 20.3097 -18.9373
17 C8x C 19.1468 -16.9371
18 C8y C 19.1468 -18.2860
19 S4a S 17.9840 -18.9373
20 C1a C 16.8210 -18.2395
21 O3c O 17.9840 -20.4962
22 C1b C 25.0421 -12.1357
23 C6a C 26.2621 -12.8232
24 O6a O 27.4570 -12.1165
25 O6a O 26.2769 -14.2361
BOND 27
1 1 2 2
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 1
7 3 8 2
8 4 9 2
9 6 10 2
10 7 11 1
11 8 12 1
12 10 13 1
13 12 14 2
14 12 15 1
15 14 16 1
16 15 17 2
17 16 18 2
18 18 19 1
19 19 20 1
20 19 21 2
21 5 7 2
22 9 10 1
23 17 18 1
24 5 22 1
25 22 23 1
26 23 24 1
27 23 25 2
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