 | | DRUG: Baclofen | |
| Entry |
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| Name |
Baclofen (JP18/USP/INN);
Kemstro (TN);
Lioresal (TN) |
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| Product |
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| Generic |
BACLOFEN (A-S Medication Solutions), BACLOFEN (A-S Medication Solutions), BACLOFEN (A-S Medication Solutions), BACLOFEN (A-S Medication Solutions), BACLOFEN (A-S Medication Solutions), BACLOFEN (A-S Medication Solutions), BACLOFEN (A-S Medication Solutions), BACLOFEN (A-S Medication Solutions), BACLOFEN (ATLANTIC BIOLOGICALS CORP.), BACLOFEN (Advagen Pharma Limited), BACLOFEN (Advanced Rx Pharmacy of Tennessee), BACLOFEN (Advanced Rx Pharmacy of Tennessee), BACLOFEN (Advanced Rx Pharmacy of Tennessee), BACLOFEN (Advanced Rx Pharmacy of Tennessee), BACLOFEN (Advanced Rx Pharmacy of Tennessee), BACLOFEN (American Health Packaging), BACLOFEN (American Health Packaging), BACLOFEN (Amneal Pharmaceuticals of New York LLC), BACLOFEN (Aphena Pharma Solutions - Tennessee), BACLOFEN (Aphena Pharma Solutions - Tennessee), BACLOFEN (Aphena Pharma Solutions - Tennessee), BACLOFEN (Aphena Pharma Solutions - Tennessee), BACLOFEN (Aphena Pharma Solutions - Tennessee), BACLOFEN (Aphena Pharma Solutions - Tennessee), BACLOFEN (Aurobindo Pharma Limited), BACLOFEN (AvKARE), BACLOFEN (AvPAK), BACLOFEN (AvPAK), BACLOFEN (Bryant Ranch Prepack), BACLOFEN (Bryant Ranch Prepack), BACLOFEN (Bryant Ranch Prepack), BACLOFEN (Bryant Ranch Prepack), BACLOFEN (Bryant Ranch Prepack), BACLOFEN (Bryant Ranch Prepack), BACLOFEN (Bryant Ranch Prepack), BACLOFEN (Bryant Ranch Prepack), BACLOFEN (Bryant Ranch Prepack), BACLOFEN (Bryant Ranch Prepack), BACLOFEN (Bryant Ranch Prepack), BACLOFEN (Bryant Ranch Prepack), BACLOFEN (Bryant Ranch Prepack), BACLOFEN (Bryant Ranch Prepack), BACLOFEN (Bryant Ranch Prepack), BACLOFEN (Bryant Ranch Prepack), BACLOFEN (Bryant Ranch Prepack), BACLOFEN (Bryant Ranch Prepack), BACLOFEN (Bryant Ranch Prepack), BACLOFEN (Bryant Ranch Prepack), BACLOFEN (Bryant Ranch Prepack), BACLOFEN (Bryant Ranch Prepack), BACLOFEN (Bryant Ranch Prepack), BACLOFEN (Bryant Ranch Prepack), BACLOFEN (Bryant Ranch Prepack), BACLOFEN (Bryant Ranch Prepack), BACLOFEN (Cadila Healthcare Limited), BACLOFEN (Camber Pharmaceuticals), BACLOFEN (Cardinal Health), BACLOFEN (DIRECT RX), BACLOFEN (DIRECT RX), BACLOFEN (Denton Pharma), BACLOFEN (Denton Pharma), BACLOFEN (Direct Rx), BACLOFEN (Direct_Rx), BACLOFEN (Direct_Rx), BACLOFEN (INTRATHECAL) (Emerald International Limited), BACLOFEN (Eywa Pharma), BACLOFEN (Kartha Pharmaceuticals), BACLOFEN (Lake Erie Medical DBA Quality Care Products LLC), BACLOFEN (Lake Erie Medical DBA Quality Care Products LLC), BACLOFEN (Lannett Company), BACLOFEN (Lifestar Pharma LLC), BACLOFEN (INTRATHECAL) (MAlA Pharmaceuticals), BACLOFEN (MAlA Pharmaceuticals), BACLOFEN (MAlA Pharmaceuticals), BACLOFEN (Major Pharmaceuticals), BACLOFEN (Marlex Pharmaceuticals), BACLOFEN (Mckesson Corporation DBA SKY Packaginng), BACLOFEN (Medsource Pharmaceuticals), BACLOFEN (Medsource Pharmaceuticals), BACLOFEN (Mylan Institutional LLC), BACLOFEN (Mylan Institutional LLC), BACLOFEN (NCS HealthCare of KY), BACLOFEN (NCS HealthCare of KY), BACLOFEN (Northstar RxLLC), BACLOFEN (NuCare Pharmaceuticals), BACLOFEN (NuCare Pharmaceuticals), BACLOFEN (NuCare Pharmaceuticals), BACLOFEN (NuCare Pharmaceuticals), BACLOFEN (NuCare Pharmaceuticals), BACLOFEN (NuCare Pharmaceuticals), BACLOFEN (NuCare Pharmaceuticals), BACLOFEN (NuCare Pharmaceuticals), BACLOFEN (PD-Rx Pharmaceuticals), BACLOFEN (PD-Rx Pharmaceuticals), BACLOFEN (Palmetto Pharmaceuticals), BACLOFEN (Par Pharmaceutical), BACLOFEN (Preferred Pharmaceuticals), BACLOFEN (Preferred Pharmaceuticals), BACLOFEN (Preferred Pharmaceuticals), BACLOFEN (Preferred Pharmaceuticals), BACLOFEN (Proficient Rx LP), BACLOFEN (Proficient Rx LP), BACLOFEN (Proficient Rx LP), BACLOFEN (Proficient Rx LP), BACLOFEN (REMEDYREPACK), BACLOFEN (REMEDYREPACK), BACLOFEN (REMEDYREPACK), BACLOFEN (REMEDYREPACK), BACLOFEN (REMEDYREPACK), BACLOFEN (REMEDYREPACK), BACLOFEN (REMEDYREPACK), BACLOFEN (Sagent Pharmaceuticals), BACLOFEN (Sagent Pharmaceuticals), BACLOFEN (Sagent Pharmaceuticals), BACLOFEN (Teva Pharmaceuticals USA), BACLOFEN (TruPharma LLC), BACLOFEN (Unichem Pharmaceuticals (USA)), BACLOFEN (Unit Dose Services), BACLOFEN (Unit Dose Services), BACLOFEN (Upsher-Smith Laboratories), BACLOFEN (Zydus Pharmaceuticals (USA)) |
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| Formula |
C10H12ClNO2
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| Exact mass |
213.0557
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| Mol weight |
213.6608
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| Structure |
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| Simcomp |
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| Class |
Neuropsychiatric agent
DG01565 GABA-B receptor agonist
Musculo-skeletal system agent
DG02029 Muscle relaxant
DG01974 Centrally acting muscle relaxant
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| Remark |
| Therapeutic category: | 1249 |
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| Efficacy |
Antispasmodic, Muscle relaxant, GABA-B receptor agonist |
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| Disease |
Multiple sclerosis [DS: H01490] |
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| Comment |
GABA (gamma-aminobutyric acid) mimetic
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| Target |
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
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| Interaction |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
M MUSCULO-SKELETAL SYSTEM
M03 MUSCLE RELAXANTS
M03B MUSCLE RELAXANTS, CENTRALLY ACTING AGENTS
M03BX Other centrally acting agents
M03BX01 Baclofen
D00241 Baclofen (JP18/USP/INN) <JP/US>
USP drug classification [BR:br08302]
Antispasticity Agents
Baclofen
D00241 Baclofen (JP18/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
12 Agents affecting peripheral nervous system
124 Antispasmodics
1249 Others
D00241 Baclofen (JP18/USP/INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01565 GABA-B receptor agonist
D00241 Baclofen
Musculo-skeletal system agent
DG02029 Muscle relaxant
DG01974 Centrally acting muscle relaxant
D00241 Baclofen
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Metabotropic glutamate receptor family
GABA (metabotropic)
GABBR
D00241 Baclofen (JP18/USP/INN) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00241 Baclofen
D00241 Baclofen tablets
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 14
1 C8y C 21.8514 -16.2984
2 C1c C 21.8514 -14.8937
3 C8x C 20.6389 -17.0038
4 C8x C 23.0637 -17.0038
5 C1b C 20.6448 -14.2001
6 C1b C 23.0637 -14.2001
7 C8x C 20.6389 -18.4027
8 C8x C 23.0637 -18.4027
9 C6a C 19.4265 -14.8937
10 N1a N 24.2820 -14.8937
11 C8y C 21.8514 -19.1022
12 O6a O 18.2140 -14.2001
13 O6a O 19.4265 -16.2984
14 X Cl 21.8514 -20.5011
BOND 14
1 1 2 1
2 1 3 1
3 1 4 2
4 2 5 1
5 2 6 1
6 3 7 2
7 4 8 1
8 5 9 1
9 6 10 1
10 7 11 1
11 9 12 1
12 9 13 2
13 11 14 1
14 8 11 2
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