KEGG   DRUG: Carmustine
Entry
D00254                      Drug                                   
Name
Carmustine (JAN/USP/INN);
Bicnu (TN);
Gliadel (TN)
Product
GLIADEL (Azurity Pharmaceuticals)
  Generic
CARMUSTINE (Alembic Pharmaceuticals Limited), CARMUSTINE (Alembic Pharmaceuticals), CARMUSTINE (Amneal Pharmaceuticals LLC), CARMUSTINE (Dr. Reddy's Laboratories), CARMUSTINE (Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals), CARMUSTINE (Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals), CARMUSTINE (KVK-Tech), CARMUSTINE (Meitheal Pharmaceuticals), CARMUSTINE (Navinta LLC), CARMUSTINE (Novadoz Pharmaceuticals LLC), CARMUSTINE (Sandoz), CARMUSTINE (Zydus Pharmaceuticals USA)
Formula
C5H9Cl2N3O2
Exact mass
213.0072
Mol weight
214.05
Structure
Simcomp
Class
Antineoplastic
 DG01677  Alkylating agent
  DG01724  Nitrosourea
Remark
Same as: C06873
Therapeutic category: 4219
ATC code: L01AD01
Product: D00254<JP/US>
Efficacy
Antineoplastic, Alkylating agent
  Disease
Glioma [DS:H00042]
Glioblastoma [DS:H00042]
Medulloblastoma [DS:H01667]
Astrocytoma [DS:H00042]
Ependymoma [DS:H00042]
Multiple myeloma [DS:H00010]
Hodgkin's lymphoma [DS:H00007]
Non-Hodgkin's lymphomas [DS:H02418]
Target
DNA
Interaction
Structure map
map07040  Antineoplastics - alkylating agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L01 ANTINEOPLASTIC AGENTS
   L01A ALKYLATING AGENTS
    L01AD Nitrosoureas
     L01AD01 Carmustine
      D00254  Carmustine (JAN/USP/INN) <JP/US>
USP drug classification [BR:br08302]
 Antineoplastics
  Alkylating Agents
   Nitrosoureas
    Carmustine
     D00254  Carmustine (JAN/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 4  Agents affecting cellular function
  42  Antineoplastics
   421  Alkylating agents
    4219  Others
     D00254  Carmustine (JAN/USP/INN)
Drug groups [BR:br08330]
 Antineoplastic
  DG01677  Alkylating agent
   DG01724  Nitrosourea
    D00254  Carmustine
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D00254
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D00254
Other DBs
CAS: 154-93-8
PubChem: 7847320
ChEBI: 3423
LigandBox: D00254
NIKKAJI: J2.968H
LinkDB
KCF data

ATOM        12
            1   N1c N    23.3800  -16.1000
            2   C5a C    22.1900  -15.4700
            3   C1b C    24.5700  -15.4700
            4   N2b N    23.3800  -17.5000
            5   N1b N    20.9300  -16.1000
            6   O5a O    22.1900  -14.0700
            7   C1b C    25.8300  -16.1000
            8   O3a O    22.1900  -18.2700
            9   C1b C    19.7400  -15.4700
            10  X   Cl   27.0200  -15.4700
            11  C1b C    18.4800  -16.1000
            12  X   Cl   17.2900  -15.4700
BOND        11
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 2
            6     3   7 1
            7     4   8 2
            8     5   9 1
            9     7  10 1
            10    9  11 1
            11   11  12 1

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