 | | DRUG: Hydrochlorothiazide | |
| Entry |
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| Name |
Hydrochlorothiazide (JP18/USP/INN);
Esidrix (TN);
Microzide (TN) |
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| Product |
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| Generic |
HYDROCHLOROTHIAZIDE (A-S Medication Solutions), HYDROCHLOROTHIAZIDE (A-S Medication Solutions), HYDROCHLOROTHIAZIDE (A-S Medication Solutions), HYDROCHLOROTHIAZIDE (A-S Medication Solutions), HYDROCHLOROTHIAZIDE (A-S Medication Solutions), HYDROCHLOROTHIAZIDE (A-S Medication Solutions), HYDROCHLOROTHIAZIDE (A-S Medication Solutions), HYDROCHLOROTHIAZIDE (A-S Medication Solutions), HYDROCHLOROTHIAZIDE (A-S Medication Solutions), HYDROCHLOROTHIAZIDE (A-S Medication Solutions), HYDROCHLOROTHIAZIDE (A-S Medication Solutions), HYDROCHLOROTHIAZIDE (A-S Medication Solutions), HYDROCHLOROTHIAZIDE (A-S Medication Solutions), HYDROCHLOROTHIAZIDE (A-S Medication Solutions), HYDROCHLOROTHIAZIDE (A-S Medication Solutions), HYDROCHLOROTHIAZIDE (A-S Medication Solutions), HYDROCHLOROTHIAZIDE (A-S Medication Solutions), HYDROCHLOROTHIAZIDE (Accord Healthcare), HYDROCHLOROTHIAZIDE (Actavis Pharma), HYDROCHLOROTHIAZIDE (Actavis Pharma), HYDROCHLOROTHIAZIDE (Alembic Pharmaceuticals Limited), HYDROCHLOROTHIAZIDE (Alembic Pharmaceuticals), HYDROCHLOROTHIAZIDE (American Health Packaging), HYDROCHLOROTHIAZIDE (American Health Packaging), HYDROCHLOROTHIAZIDE (Aphena Pharma Solutions - Tennessee), HYDROCHLOROTHIAZIDE (Aphena Pharma Solutions - Tennessee), HYDROCHLOROTHIAZIDE (Aphena Pharma Solutions - Tennessee), HYDROCHLOROTHIAZIDE (Aphena Pharma Solutions - Tennessee), HYDROCHLOROTHIAZIDE (Aphena Pharma Solutions - Tennessee), HYDROCHLOROTHIAZIDE (Aphena Pharma Solutions - Tennessee), HYDROCHLOROTHIAZIDE (Aphena Pharma Solutions - Tennessee), HYDROCHLOROTHIAZIDE (Aphena Pharma Solutions - Tennessee), HYDROCHLOROTHIAZIDE (Aphena Pharma Solutions - Tennessee), HYDROCHLOROTHIAZIDE (Aphena Pharma Solutions - Tennessee), HYDROCHLOROTHIAZIDE (Aphena Pharma Solutions - Tennessee), HYDROCHLOROTHIAZIDE (Aurobindo Pharma Limited), HYDROCHLOROTHIAZIDE (Aurobindo Pharma Limited), HYDROCHLOROTHIAZIDE (AvPAK), HYDROCHLOROTHIAZIDE (Bryant Ranch Prepack), HYDROCHLOROTHIAZIDE (Bryant Ranch Prepack), HYDROCHLOROTHIAZIDE (Bryant Ranch Prepack), HYDROCHLOROTHIAZIDE (Bryant Ranch Prepack), HYDROCHLOROTHIAZIDE (Bryant Ranch Prepack), HYDROCHLOROTHIAZIDE (Bryant Ranch Prepack), HYDROCHLOROTHIAZIDE (Bryant Ranch Prepack), HYDROCHLOROTHIAZIDE (Bryant Ranch Prepack), HYDROCHLOROTHIAZIDE (Bryant Ranch Prepack), HYDROCHLOROTHIAZIDE (Bryant Ranch Prepack), HYDROCHLOROTHIAZIDE (Bryant Ranch Prepack), HYDROCHLOROTHIAZIDE (Bryant Ranch Prepack), HYDROCHLOROTHIAZIDE (Bryant Ranch Prepack), HYDROCHLOROTHIAZIDE (Bryant Ranch Prepack), HYDROCHLOROTHIAZIDE (Bryant Ranch Prepack), HYDROCHLOROTHIAZIDE (Bryant Ranch Prepack), HYDROCHLOROTHIAZIDE (Bryant Ranch Prepack), HYDROCHLOROTHIAZIDE (Bryant Ranch Prepack), HYDROCHLOROTHIAZIDE (Bryant Ranch Prepack), HYDROCHLOROTHIAZIDE (Chartwell RX), HYDROCHLOROTHIAZIDE (Coupler LLC), HYDROCHLOROTHIAZIDE (Coupler LLC), HYDROCHLOROTHIAZIDE (Coupler LLC), HYDROCHLOROTHIAZIDE (DIRECT RX), HYDROCHLOROTHIAZIDE (Direct_Rx), HYDROCHLOROTHIAZIDE (Exelan Pharmaceuticals), HYDROCHLOROTHIAZIDE (Golden State Medical Supply), HYDROCHLOROTHIAZIDE (Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals), HYDROCHLOROTHIAZIDE (JUBILANT CADISTA PHARMACEUTICALS), HYDROCHLOROTHIAZIDE (Lake Erie Medical DBA Quality Care Products LLC), HYDROCHLOROTHIAZIDE (Leading Pharma), HYDROCHLOROTHIAZIDE (Legacy Pharmaceutical Packaging), HYDROCHLOROTHIAZIDE (NCS HealthCare of KY), HYDROCHLOROTHIAZIDE (NCS HealthCare of KY), HYDROCHLOROTHIAZIDE (NCS HealthCare of KY), HYDROCHLOROTHIAZIDE (Northwind Pharmaceuticals), HYDROCHLOROTHIAZIDE (Northwind Pharmaceuticals), HYDROCHLOROTHIAZIDE (Northwind Pharmaceuticals), HYDROCHLOROTHIAZIDE (Northwind Pharmaceuticals), HYDROCHLOROTHIAZIDE (Northwind Pharmaceuticals), HYDROCHLOROTHIAZIDE (Northwind Pharmaceuticals), HYDROCHLOROTHIAZIDE (Northwind Pharmaceuticals), HYDROCHLOROTHIAZIDE (Northwind Pharmaceuticals), HYDROCHLOROTHIAZIDE (Northwind Pharmaceuticals), HYDROCHLOROTHIAZIDE (Northwind Pharmaceuticals), HYDROCHLOROTHIAZIDE (Northwind Pharmaceuticals), HYDROCHLOROTHIAZIDE (NuCare Pharmaceuticals), HYDROCHLOROTHIAZIDE (NuCare Pharmaceuticals), HYDROCHLOROTHIAZIDE (NuCare Pharmaceuticals), HYDROCHLOROTHIAZIDE (NuCare Pharmaceuticals), HYDROCHLOROTHIAZIDE (NuCare Pharmaceuticals), HYDROCHLOROTHIAZIDE (NuCare Pharmaceuticals), HYDROCHLOROTHIAZIDE (NuCare Pharmaceuticals), HYDROCHLOROTHIAZIDE (NuCare Pharmaceuticals), HYDROCHLOROTHIAZIDE (NuCare Pharmaceuticals), HYDROCHLOROTHIAZIDE (Oxford Pharmaceuticals), HYDROCHLOROTHIAZIDE (PD-Rx Pharmaceuticals), HYDROCHLOROTHIAZIDE (PD-Rx Pharmaceuticals), HYDROCHLOROTHIAZIDE (PD-Rx Pharmaceuticals), HYDROCHLOROTHIAZIDE (PD-Rx Pharmaceuticals), HYDROCHLOROTHIAZIDE (PD-Rx Pharmaceuticals), HYDROCHLOROTHIAZIDE (PD-Rx Pharmaceuticals), HYDROCHLOROTHIAZIDE (PD-Rx Pharmaceuticals), HYDROCHLOROTHIAZIDE (Preferred Pharmaceuticals), HYDROCHLOROTHIAZIDE (Preferred Pharmaceuticals), HYDROCHLOROTHIAZIDE (Preferred Pharmaceuticals), HYDROCHLOROTHIAZIDE (Preferred Pharmaceuticals), HYDROCHLOROTHIAZIDE (Preferred Pharmaceuticals), HYDROCHLOROTHIAZIDE (Preferred Pharmaceuticals), HYDROCHLOROTHIAZIDE (Preferred Pharmaceuticals), HYDROCHLOROTHIAZIDE (Proficient Rx LP), HYDROCHLOROTHIAZIDE (Proficient Rx LP), HYDROCHLOROTHIAZIDE (Proficient Rx LP), HYDROCHLOROTHIAZIDE (Proficient Rx LP), HYDROCHLOROTHIAZIDE (Proficient Rx LP), HYDROCHLOROTHIAZIDE (Proficient Rx LP), HYDROCHLOROTHIAZIDE (Proficient Rx LP), HYDROCHLOROTHIAZIDE (Proficient Rx LP), HYDROCHLOROTHIAZIDE (Proficient Rx LP), HYDROCHLOROTHIAZIDE (Proficient Rx LP), HYDROCHLOROTHIAZIDE (Proficient Rx LP), HYDROCHLOROTHIAZIDE (Proficient Rx LP), HYDROCHLOROTHIAZIDE (Proficient Rx LP), HYDROCHLOROTHIAZIDE (Proficient Rx LP), HYDROCHLOROTHIAZIDE (QPharma), HYDROCHLOROTHIAZIDE (QPharma), HYDROCHLOROTHIAZIDE (QPharma), HYDROCHLOROTHIAZIDE (QPharma), HYDROCHLOROTHIAZIDE (QPharma), HYDROCHLOROTHIAZIDE (Quality Care Products LLC), HYDROCHLOROTHIAZIDE (REMEDYREPACK), HYDROCHLOROTHIAZIDE (REMEDYREPACK), HYDROCHLOROTHIAZIDE (REMEDYREPACK), HYDROCHLOROTHIAZIDE (REMEDYREPACK), HYDROCHLOROTHIAZIDE (REMEDYREPACK), HYDROCHLOROTHIAZIDE (REMEDYREPACK), HYDROCHLOROTHIAZIDE (REMEDYREPACK), HYDROCHLOROTHIAZIDE (RedPharm Drug), HYDROCHLOROTHIAZIDE (RedPharm Drug), HYDROCHLOROTHIAZIDE (Redpharm Drug), HYDROCHLOROTHIAZIDE (Redpharm drug), HYDROCHLOROTHIAZIDE (Rising Pharma Holdings), HYDROCHLOROTHIAZIDE (ST. MARY'S MEDICAL PARK PHARMACY), HYDROCHLOROTHIAZIDE (ScieGen Pharmaceuticals), HYDROCHLOROTHIAZIDE (ScieGen Pharmaceuticals), HYDROCHLOROTHIAZIDE (Solco Healthcare U.S.), HYDROCHLOROTHIAZIDE (St. Mary's Medical Park Pharmacy), HYDROCHLOROTHIAZIDE (St. Mary's Medical Park Pharmacy), HYDROCHLOROTHIAZIDE (Teva Pharmaceuticals USA), HYDROCHLOROTHIAZIDE (Unichem Pharmaceuticals (USA)), HYDROCHLOROTHIAZIDE (Unichem Pharmaceuticals (USA)), HYDROCHLOROTHIAZIDE (Westminster Pharmaceuticals) |
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| Formula |
C7H8ClN3O4S2
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| Exact mass |
296.9645
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| Mol weight |
297.74
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| Structure |
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| Simcomp |
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| Class |
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| Remark |
| Product (mixture): | D07895<JP/US> D09196<JP/US> D09197<JP/US> D09219<JP/US> D10249<US> D10268<US> D10269<US> D10270<US> D10271<US> D10273<US> D10275<US> D10276<US> D10277<US> D10278<US> D10279<US> D10280<US> D10284<US> D10286<US> D10288<US> D10805<JP> |
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| Efficacy |
Antihypertensive, Diuretic, Na+-Cl- symport inhibitor |
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| Disease |
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| Comment |
Thiazides
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| Target |
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| Interaction |
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| Structure map |
| map07017 | Sulfonamide derivatives - diuretics |
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| Other map |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C03 DIURETICS
C03A LOW-CEILING DIURETICS, THIAZIDES
C03AA Thiazides, plain
C03AA03 Hydrochlorothiazide
D00340 Hydrochlorothiazide (JP18/USP/INN) <JP/US>
USP drug classification [BR:br08302]
Cardiovascular Agents
Diuretics, Thiazide
Hydrochlorothiazide
D00340 Hydrochlorothiazide (JP18/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
21 Cardiovascular agents
213 Diuretics
2132 Thiazides
D00340 Hydrochlorothiazide (JP18/USP/INN)
214 Antihypertensives
2149 Others
D00340 Hydrochlorothiazide (JP18/USP/INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG03231 Antihypertensive
DG01749 Thiazide diuretic
D00340 Hydrochlorothiazide
DG01690 Sulfonamide diuretic
DG01749 Thiazide diuretic
D00340 Hydrochlorothiazide
Drug classes [BR:br08332]
Cardiovascular agent
DG03231 Antihypertensive
D00340 Hydrochlorothiazide
Target-based classification of drugs [BR:br08310]
Transporters
Solute carrier family
SLC12
SLC12A3 (TSC)
D00340 Hydrochlorothiazide (JP18/USP/INN) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00340 Hydrochlorothiazide
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 17
1 C8y C 22.4791 -15.9596
2 C8y C 22.4731 -17.3165
3 C8x C 23.6605 -15.2870
4 S2x S 21.3034 -15.2811
5 C8x C 23.6430 -18.0010
6 N1x N 21.3034 -17.9950
7 C8y C 24.8304 -15.9713
8 N1x N 20.1278 -15.9596
9 O3c O 19.9933 -14.4564
10 O3c O 22.5376 -14.4564
11 C8y C 24.8244 -17.3282
12 C1x C 20.1278 -17.3165
13 S4a S 26.0118 -15.2987
14 X Cl 26.0003 -18.0127
15 N1a N 27.2636 -14.4623
16 O3c O 27.1349 -16.3164
17 O3c O 24.9357 -14.2516
BOND 18
1 1 2 2
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 2
7 4 8 1
8 4 9 2
9 4 10 2
10 5 11 2
11 6 12 1
12 7 13 1
13 11 14 1
14 13 15 1
15 13 16 2
16 13 17 2
17 7 11 1
18 8 12 1
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