Entry |
|
Name |
Indapamide (JP18/USP); Lozol (TN); Natrix (TN) |
Product |
|
Generic |
|
Formula |
C16H16ClN3O3S
|
Exact mass |
365.0601
|
Mol weight |
365.84
|
Structure |
|
Simcomp |
|
Class |
Cardiovascular agent
DG03231 Antihypertensive
DG02992 Thiazide related diuretic
DG01690 Sulfonamide diuretic
DG02992 Thiazide related diuretic
|
Remark |
Therapeutic category: | 2149 |
Product (DG00269): | D00345<JP/US> |
|
Efficacy |
Antihypertensive, Diuretic, Na+-Cl- symport inhibitor |
Disease |
|
Comment |
Sulfonamide derivative
|
Target |
|
Interaction |
|
Structure map |
map07017 | Sulfonamide derivatives - diuretics |
map07055 | Sulfonamide derivatives - overview |
|
Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C03 DIURETICS
C03B LOW-CEILING DIURETICS, EXCL. THIAZIDES
C03BA Sulfonamides, plain
C03BA11 Indapamide
D00345 Indapamide (JP18/USP) <JP/US>
USP drug classification [BR:br08302]
Cardiovascular Agents
Diuretics, Thiazide
Indapamide
D00345 Indapamide (JP18/USP)
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
21 Cardiovascular agents
214 Antihypertensives
2149 Others
D00345 Indapamide (JP18/USP)
Drug groups [BR:br08330]
Cardiovascular agent
DG03231 Antihypertensive
DG02992 Thiazide related diuretic
DG00269 Indapamide
D00345 Indapamide
DG01690 Sulfonamide diuretic
DG02992 Thiazide related diuretic
DG00269 Indapamide
D00345 Indapamide
Drug classes [BR:br08332]
Cardiovascular agent
DG02992 Thiazide related diuretic
D00345 Indapamide
DG03231 Antihypertensive
D00345 Indapamide
Target-based classification of drugs [BR:br08310]
Transporters
Solute carrier family
SLC12
SLC12A3 (TSC)
D00345 Indapamide (JP18/USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00345 Indapamide
D00345 Indapamide tablets
Drug groups [BR:br08330]
Cardiovascular agent
DG03231 Antihypertensive
DG02992 Thiazide related diuretic
DG00269 Indapamide
DG01690 Sulfonamide diuretic
DG02992 Thiazide related diuretic
DG00269 Indapamide
|
Other DBs |
|
LinkDB |
|
KCF data |
ATOM 24
1 C8x C 16.4080 -16.4924
2 C8x C 16.4080 -17.8843
3 C8x C 17.6134 -18.5803
4 C8x C 18.8190 -17.8843
5 C8y C 18.8190 -16.4924
6 C8y C 17.6134 -15.7964
7 N1y N 20.0245 -15.7964
8 C1y C 19.5262 -14.4348
9 C1x C 18.0723 -14.4284
10 N1b N 21.2300 -16.4924
11 C5a C 22.4355 -15.7964
12 C1a C 20.3390 -13.2774
13 C8y C 23.6841 -16.5171
14 O5a O 22.4361 -14.4204
15 C8x C 23.6842 -17.9198
16 C8x C 24.8967 -18.6197
17 C8y C 26.1091 -17.9196
18 C8y C 26.1090 -16.5169
19 C8x C 24.8965 -15.8170
20 S4a S 27.3208 -15.8172
21 X Cl 27.3224 -18.6200
22 N1a N 28.5332 -15.1172
23 O3c O 26.6169 -14.5979
24 O3c O 28.0167 -17.0226
BOND 26
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 5 7 1
8 7 8 1
9 8 9 1
10 9 6 1
11 10 11 1
12 7 10 1
13 8 12 1
14 11 13 1
15 11 14 2
16 13 15 2
17 15 16 1
18 16 17 2
19 17 18 1
20 18 19 2
21 13 19 1
22 18 20 1
23 17 21 1
24 20 22 1
25 20 23 2
26 20 24 2
|