KEGG   DRUG: Lactulose
Entry
D00352                      Drug                                   

Name
Lactulose (JP18/USP/INN);
Cephulac (TN);
Chronulac (TN)
Product
  Generic
CONSTULOSE (A-S Medication Solutions), ENULOSE (Actavis Pharma), CONSTULOSE (Actavis Pharma), LACTULOSE (Atlantic Biologicals Corps), LACTULOSE (Cardinal Health), LACTULOSE (Cardinal Health), LACTULOSE (Chartwell RX), KRISTALOSE (Cumberland Pharmaceuticals), LACTULOSE (Foxland Pharmaceuticals), LACTULOSE (Fresenius Kabi Austria GmbH), LACTULOSE (Hi-Tech Pharmacal), LACTULOSE (Hi-Tech Pharmacal), LACTULOSE (Lannett Company), LACTULOSE (Lannett Company), GENERLAC (Morton Grove Pharmaceuticals), LACTULOSE (Morton Grove Pharmaceuticals), LACTULOSE (NuCare Pharmaceuticals), LACTULOSE (Pharmaceutical Associates), LACTULOSE (Pharmaceutical Associates), LACTULOSE (Quality Care Products), LACTULOSE (Quality Care Products), LACTULOSE (Torrent Pharmaceuticals Limited), LACTULOSE (VistaPharm), LACTULOSE SOLUTION (TriRx Huntsville Pharmaceutical Services), LACTULOSE SOLUTION (TriRx Huntsville Pharmaceutical Services)
Formula
C12H22O11
Exact mass
342.1162
Mol weight
342.2965
Structure
Simcomp
Class
Gastrointestinal agent
 DG01770  Laxative
  DG01767  Osmotic laxative
Remark
Same as: C07064 G03573
Therapeutic category: 2359 3999
ATC code: A06AD11
Product: D00352<JP/US>
Efficacy
Antihyperammonemic, Laxative
Comment
Non-digestible disaccharide
synthetic
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A06 DRUGS FOR CONSTIPATION
   A06A DRUGS FOR CONSTIPATION
    A06AD Osmotically acting laxatives
     A06AD11 Lactulose
      D00352  Lactulose (JP18/USP/INN) <JP/US>
USP drug classification [BR:br08302]
 Gastrointestinal Agents
  Anti-Constipation Agents
   Lactulose
    D00352  Lactulose (JP18/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  23  Digestive organ agents
   235  Purgatives, clysters
    2359  Others
     D00352  Lactulose (JP18/USP/INN)
 3  Agents affecting metabolism
  39  Other agents affecting metabolism
   399  Miscellaneous
    3999  Others
     D00352  Lactulose (JP18/USP/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00352  Lactulose
Other DBs
CAS: 4618-18-2
PubChem: 7847418
ChEBI: 6359
ChEMBL: CHEMBL296306
DrugBank: DB00581
PDB-CCD: W9T[PDBj]
LigandBox: D00352
NIKKAJI: J208.671I J86.091C
LinkDB
KCF data

ATOM        23
            1   C1y C    23.1356  -15.2363
            2   C1y C    22.7097  -13.9231
            3   C1y C    24.5187  -15.2363
            4   O2a O    22.0969  -16.5027
            5   O2x O    23.8300  -13.1062
            6   C1b C    21.5775  -13.2228
            7   C1z C    24.9446  -13.9231
            8   O1a O    25.3298  -16.3568
            9   C1y C    20.8946  -17.1913
            10  O1a O    20.3869  -13.8473
            11  C1b C    26.1877  -13.2228
            12  O1a O    26.2637  -14.8160
            13  O2x O    19.7042  -16.5027
            14  C1y C    20.8946  -18.5743
            15  O1a O    27.3783  -13.9174
            16  C1y C    18.5019  -17.1913
            17  C1y C    19.7042  -19.2629
            18  O1a O    22.0969  -19.2629
            19  C1y C    18.5019  -18.5743
            20  C1b C    17.2998  -16.5027
            21  O1a O    19.7042  -20.6459
            22  O1a O    17.2998  -19.2629
            23  O1a O    16.1035  -17.1913
BOND        24
            1     1   2 1
            2     1   3 1
            3     1   4 1 #Down
            4     2   5 1
            5     2   6 1 #Up
            6     3   7 1
            7     3   8 1 #Up
            8     9   4 1 #Up
            9     6  10 1
            10    7  11 1 #Down
            11    7  12 1 #Up
            12    9  13 1
            13    9  14 1
            14   11  15 1
            15   13  16 1
            16   14  17 1
            17   14  18 1 #Down
            18   16  19 1
            19   16  20 1 #Up
            20   17  21 1 #Up
            21   19  22 1 #Up
            22   20  23 1
            23    5   7 1
            24   17  19 1

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