| Entry |
|
|---|
| Name |
Pseudoephedrine hydrochloride (USP);
Sudafed (TN) |
|---|
| Formula |
C10H15NO. HCl
|
|---|
| Exact mass |
201.092
|
|---|
| Mol weight |
201.6931
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01456 Adrenergic receptor agonist
|
|---|
| Remark |
| Product (mixture): | D10252<JP> D11647<US> |
|
|---|
| Efficacy |
Vasoconstrictor, Adrenergic receptor agonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04270 | Vascular smooth muscle contraction |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
R RESPIRATORY SYSTEM
R01 NASAL PREPARATIONS
R01B NASAL DECONGESTANTS FOR SYSTEMIC USE
R01BA Sympathomimetics
R01BA02 Pseudoephedrine
D00485 Pseudoephedrine hydrochloride (USP)
Classification of Japanese OTC drugs [BR:br08313]
Agents for otolaryngologic use
69 Oral medicine for nasal inflammation
D00485 Pseudoephedrine hydrochloride (USP)
Risk category of Japanese OTC drugs [BR:br08312]
Designated second-class OTC drugs
Inorganic and organic chemicals
Pseudoephedrine
D00485 Pseudoephedrine hydrochloride (USP)
Second-class OTC drugs
Inorganic and organic chemicals
Pseudoephedrine
D00485 Pseudoephedrine hydrochloride (USP)
Drug groups [BR:br08330]
Cardiovascular agent
DG01456 Adrenergic receptor agonist
DG01042 Pseudoephedrine
D00485 Pseudoephedrine hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRA1
D00485 Pseudoephedrine hydrochloride (USP)
ADRA2
D00485 Pseudoephedrine hydrochloride (USP)
ADRB
D00485 Pseudoephedrine hydrochloride (USP)
Rx-to-OTC switch list in the USA [br08315.html]
D00485
Drug groups [BR:br08330]
Cardiovascular agent
DG01456 Adrenergic receptor agonist
DG01042 Pseudoephedrine
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 13
1 X Cl 31.6713 -29.5074
2 C8x C 21.1400 -29.6100
3 C8x C 21.1400 -31.0100
4 C8x C 22.3524 -31.7100
5 C8x C 23.5649 -31.0100
6 C8y C 23.5649 -29.6100
7 C8x C 22.3524 -28.9100
8 C1c C 24.7960 -28.8990
9 C1c C 26.0012 -29.5947
10 O1a O 24.7957 -27.5101
11 N1b N 27.1835 -28.9119
12 C1a C 26.0016 -31.0096
13 C1a C 28.3775 -29.6012
BOND 12
1 2 3 2
2 3 4 1
3 4 5 2
4 5 6 1
5 6 7 2
6 2 7 1
7 6 8 1
8 8 9 1
9 8 10 1 #Down
10 9 11 1
11 9 12 1 #Up
12 11 13 1
|
|---|
