| Entry |
|
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| Name |
Levofloxacin (USP);
Levofloxacin hydrate (JP18);
Levofloxacin hemihydrate;
Iquix (TN);
Levaquin (TN);
Quixin (TN) |
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| Product |
|
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| Generic |
LEVOFLOXACIN (A-S Medication Solutions), LEVOFLOXACIN (A-S Medication Solutions), LEVOFLOXACIN (A-S Medication Solutions), LEVOFLOXACIN (A-S Medication Solutions), LEVOFLOXACIN (A-S Medication Solutions), LEVOFLOXACIN (ADVANCED RX PHARMACY OF TENNESSEE), LEVOFLOXACIN (ANI Pharmaceuticals), LEVOFLOXACIN (Advagen Pharma Limited), LEVOFLOXACIN (Advanced Rx Pharmacy of Tennessee), LEVOFLOXACIN (Advanced Rx of Tennessee), LEVOFLOXACIN (Advanced Rx of Tennessee), LEVOFLOXACIN (Advanced Rx of Tennessee), LEVOFLOXACIN (Advanced Rx of Tennessee), LEVOFLOXACIN (Asclemed USA), LEVOFLOXACIN (Aurobindo Pharma Limited), LEVOFLOXACIN (BPI LABS LLC), LEVOFLOXACIN (Baxter Healthcare Corporation), LEVOFLOXACIN (Bryant Ranch Prepack), LEVOFLOXACIN (Bryant Ranch Prepack), LEVOFLOXACIN (Bryant Ranch Prepack), LEVOFLOXACIN (Bryant Ranch Prepack), LEVOFLOXACIN (Bryant Ranch Prepack), LEVOFLOXACIN (Bryant Ranch Prepack), LEVOFLOXACIN (Bryant Ranch Prepack), LEVOFLOXACIN (Camber Pharmaceuticals), LEVOFLOXACIN (Cardinal Health 107), LEVOFLOXACIN (Chartwell RX), LEVOFLOXACIN (Coupler LLC), LEVOFLOXACIN (DirectRx), LEVOFLOXACIN (Dr. Reddy's Laboratories Limited), LEVOFLOXACIN (Eugia US LLC), LEVOFLOXACIN (Eugia US LLC), LEVOFLOXACIN (Fresenius Kabi USA), LEVOFLOXACIN (Gland Pharma Limited), LEVOFLOXACIN (Gland Pharma Limited), LEVOFLOXACIN (Golden State Medical Supply), LEVOFLOXACIN (Hikma Pharmaceuticals USA), LEVOFLOXACIN (Hikma Pharmaceuticals USA), LEVOFLOXACIN (Hospira), LEVOFLOXACIN (Hospira), LEVOFLOXACIN (Lannett Company), LEVOFLOXACIN (Lupin Pharmaceuticals), LEVOFLOXACIN (Macleods Pharmaceuticals Limited), LEVOFLOXACIN (Macleods Pharmaceuticals Limited), LEVOFLOXACIN (Major Pharmaceuticals), LEVOFLOXACIN (Micro Labs Limited), LEVOFLOXACIN (Northwind Pharmaceuticals), LEVOFLOXACIN (Northwind Pharmaceuticals), LEVOFLOXACIN (Northwind Pharmaceuticals), LEVOFLOXACIN (NuCare Pharmaceuticals), LEVOFLOXACIN (NuCare Pharmaceuticals), LEVOFLOXACIN (NuCare Pharmaceuticals), LEVOFLOXACIN (NuCare Pharmaceuticals), LEVOFLOXACIN (NuCare Pharmaceuticals), LEVOFLOXACIN (NuCare Pharmaceuticals), LEVOFLOXACIN (NuCare Pharmaceuticals), LEVOFLOXACIN (NuCare Pharmaceuticals), LEVOFLOXACIN (NuCare Pharmaceuticals), LEVOFLOXACIN (NuCare Pharmaceuticals), LEVOFLOXACIN (NuCarePharmaceuticals), LEVOFLOXACIN (PD-Rx Pharmaceuticals), LEVOFLOXACIN (PD-Rx Pharmaceuticals), LEVOFLOXACIN (PD-Rx Pharmaceuticals), LEVOFLOXACIN (PD-Rx Pharmaceuticals), LEVOFLOXACIN (PD-Rx Pharmaceuticals), LEVOFLOXACIN (PD-Rx Pharmaceuticals), LEVOFLOXACIN (PD-Rx Pharmaceuticals), LEVOFLOXACIN (PD-Rx Pharmaceuticals), LEVOFLOXACIN (Pharmasource Meds), LEVOFLOXACIN (Preferred Pharmaceuticals), LEVOFLOXACIN (Preferred Pharmaceuticals), LEVOFLOXACIN (Preferred Pharmaceuticals), LEVOFLOXACIN (Preferred Pharmaceuticals), LEVOFLOXACIN (Proficient Rx LP), LEVOFLOXACIN (Proficient Rx LP), LEVOFLOXACIN (Proficient Rx LP), LEVOFLOXACIN (Proficient Rx LP), LEVOFLOXACIN (Proficient Rx LP), LEVOFLOXACIN (Proficient Rx LP), LEVOFLOXACIN (Proficient Rx LP), LEVOFLOXACIN (Proficient Rx LP), LEVOFLOXACIN (Proficient Rx), LEVOFLOXACIN (REMEDYREPACK), LEVOFLOXACIN (REMEDYREPACK), LEVOFLOXACIN (REMEDYREPACK), LEVOFLOXACIN (REMEDYREPACK), LEVOFLOXACIN (REMEDYREPACK), LEVOFLOXACIN (REMEDYREPACK), LEVOFLOXACIN (RedPharm Drug), LEVOFLOXACIN (RedPharm Drug), LEVOFLOXACIN (RedPharm Drug), LEVOFLOXACIN (RedPharm Drug), LEVOFLOXACIN (RedPharm Drug), LEVOFLOXACIN (Redpharm Drug), LEVOFLOXACIN (Redpharm Drug), LEVOFLOXACIN (Sagent Pharmaceuticals), LEVOFLOXACIN (Viona Pharmaceuticals), LEVOFLOXACIN (WG Critical Care), LEVOFLOXACIN (Zydus Lifesciences Limited), LEVOFLOXACIN (Zydus Lifesciences Limited), LEVOFLOXACIN (Zydus Pharmaceuticals USA) |
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| Formula |
(C18H20FN3O4)2. H2O
|
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| Exact mass |
740.2981
|
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| Mol weight |
740.75
|
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| Structure |
|
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| Simcomp |
|
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| Class |
|
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| Remark |
| Product (DG00624): | D00588<JP/US> |
|
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| Efficacy |
Antibacterial, Nucleic acid biosynthesis inhibitor |
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| Disease |
Inhalational anthrax [DS: H00328] Plague [DS: H00297] Uncomplicated urinary tract infections [DS: H01176] |
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| Target |
|
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| Metabolism |
Transporter: SLCO1A2 [HSA: 6579]
|
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| Interaction |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01M QUINOLONE ANTIBACTERIALS
J01MA Fluoroquinolones
J01MA12 Levofloxacin
D00588 Levofloxacin (USP) <JP/US>
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01A ANTIINFECTIVES
S01AE Fluoroquinolones
S01AE05 Levofloxacin
D00588 Levofloxacin (USP) <JP/US>
USP drug classification [BR:br08302]
Antibacterials
Quinolones
Levofloxacin
D00588 Levofloxacin (USP)
Ophthalmic Agents
Ophthalmic Anti-Infectives
Antibacterials, Ophthalmic
Levofloxacin
D00588 Levofloxacin (USP)
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
13 Agents affecting sensory organs
131 Ophthalmic agents
1319 Others
D00588 Levofloxacin (USP); Levofloxacin hydrate (JP18)
132 Otic and nasal agents
1329 Others
D00588 Levofloxacin (USP); Levofloxacin hydrate (JP18)
6 Agents against pathologic organisms and parasites
62 Chemotherapeutics
624 Synthetic antibacterials
6241 Pyridonecarboxylic acids
D00588 Levofloxacin (USP); Levofloxacin hydrate (JP18)
Drug groups [BR:br08330]
Antibacterial
DG01550 Quinolone
DG01549 Fluoroquinolone
DG00624 Levofloxacin
D00588 Levofloxacin
DG01966 Antitubercular
DG00624 Levofloxacin
D00588 Levofloxacin
Transporter substrate
DG02857 SLCO1A2 substrate
DG00624 Levofloxacin
D00588 Levofloxacin
Drug classes [BR:br08332]
Antibacterial
DG01549 Fluoroquinolone
D00588 Levofloxacin
Antimicrobials [BR:br08307]
Antibacterials
Nucleic acid synthesis inhibitor
Fluoroquinolone
D00588 Levofloxacin (USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00588 Levofloxacin hydrate
D00588 Levofloxacin tablets
D00588 Levofloxacin fine granules
D00588 Levofloxacin injection
D00588 Levofloxacin ophthalmic solution
New drug approvals in Europe [br08329.html]
European public assessment reports (EPAR) authorised medicine
D00588
Drug metabolizing enzymes and transporters [br08309.html]
Drug transporters
D00588
Drug groups [BR:br08330]
Antibacterial
DG01550 Quinolone
DG01549 Fluoroquinolone
DG00624 Levofloxacin
DG01966 Antitubercular
DG00624 Levofloxacin
Transporter substrate
DG02857 SLCO1A2 substrate
DG00624 Levofloxacin
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Nucleic acid synthesis inhibitor
Fluoroquinolone
DG00624 Levofloxacin
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 53
1 C8y C 25.5128 -19.2413
2 C8y C 24.2948 -19.9406
3 C8y C 25.5070 -17.8485
4 N4y N 26.7249 -19.9406
5 C8y C 23.0828 -19.2354
6 O2x O 24.2948 -21.3449
7 C8y C 26.7133 -17.1434
8 C8x C 24.3007 -17.1318
9 C8x C 27.9312 -19.2354
10 C1y C 26.7249 -21.3449
11 N1y N 21.8590 -19.9406
12 C8y C 23.0828 -17.8311
13 C1x C 25.5128 -22.0383
14 C8y C 27.9312 -17.8368
15 O5x O 26.7074 -15.7506
16 C1a C 27.9312 -22.0442
17 C1x C 21.8532 -21.3449
18 C1x C 20.6470 -19.2296
19 X F 21.8590 -17.1434
20 C6a C 29.1316 -17.1434
21 C1x C 20.6353 -22.0325
22 C1x C 19.4407 -19.9289
23 O6a O 30.3378 -17.8427
24 O6a O 29.1258 -15.7448
25 N1y N 19.4290 -21.3333
26 C1a C 18.2111 -22.0325
27 O0 O 34.9829 -18.9205
28 C8y C 25.5128 -19.2413
29 C8y C 24.2948 -19.9406
30 C8y C 23.0828 -19.2354
31 N1y N 21.8590 -19.9406
32 C1x C 21.8532 -21.3449
33 C1x C 20.6353 -22.0325
34 N1y N 19.4290 -21.3333
35 C1a C 18.2111 -22.0325
36 C1x C 19.4407 -19.9289
37 C1x C 20.6470 -19.2296
38 C8y C 23.0828 -17.8311
39 C8x C 24.3007 -17.1318
40 C8y C 25.5070 -17.8485
41 C8y C 26.7133 -17.1434
42 C8y C 27.9312 -17.8368
43 C8x C 27.9312 -19.2354
44 N4y N 26.7249 -19.9406
45 C1y C 26.7249 -21.3449
46 C1x C 25.5128 -22.0383
47 O2x O 24.2948 -21.3449
48 C1a C 27.9312 -22.0442
49 C6a C 29.1316 -17.1434
50 O6a O 30.3378 -17.8427
51 O6a O 29.1258 -15.7448
52 O5x O 26.7074 -15.7506
53 X F 21.8590 -17.1434
BOND 58
1 25 26 1
2 8 12 2
3 9 14 2
4 10 13 1
5 22 25 1
6 1 2 1
7 1 3 2
8 1 4 1
9 2 5 2
10 2 6 1
11 3 7 1
12 3 8 1
13 4 9 1
14 4 10 1
15 5 11 1
16 5 12 1
17 6 13 1
18 7 14 1
19 7 15 2
20 10 16 1 #Up
21 11 17 1
22 11 18 1
23 12 19 1
24 14 20 1
25 17 21 1
26 18 22 1
27 20 23 1
28 20 24 2
29 21 25 1
30 34 35 1
31 39 38 2
32 43 42 2
33 45 46 1
34 36 34 1
35 28 29 1
36 28 40 2
37 28 44 1
38 29 30 2
39 29 47 1
40 40 41 1
41 40 39 1
42 44 43 1
43 44 45 1
44 30 31 1
45 30 38 1
46 47 46 1
47 41 42 1
48 41 52 2
49 45 48 1 #Up
50 31 32 1
51 31 37 1
52 38 53 1
53 42 49 1
54 32 33 1
55 37 36 1
56 49 50 1
57 49 51 2
58 33 34 1
BRACKET 1 16.7300 -23.0300 16.7300 -15.1200
1 31.5700 -15.1200 31.5700 -23.0300
1 2
ORIGINAL 1 1 2 5 11 17 21 25 26 22 18 12 8 3 7 14 9
1 4 10 13 6 16 20 23 24 15 19
REPEAT 1 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43
1 44 45 46 47 48 49 50 51 52 53
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