KEGG   DRUG: Chloroprocaine hydrochlorideHelp
Entry
D00732                      Drug                                   

Name
Chloroprocaine hydrochloride (USP);
Clorotekal (TN);
Nesacaine (TN)
Product
  Generic
Formula
C13H19ClN2O2. HCl
Exact mass
306.0902
Mol weight
307.2161
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Neuropsychiatric agent
 DG02030  Anesthetics
  DG01675  Local anesthetic
   DG01674  Esterified local anesthetic
 DG01675  Local anesthetic
  DG01674  Esterified local anesthetic
Remark
ATC code: N01BA04
Chemical structure group: DG00800
Product (DG00800): D00732<US>
Efficacy
Anesthetic (local)
Comment
Ester-type
Target
SCN1A [HSA:6323] [KO:K04833]
SCN2A [HSA:6326] [KO:K04834]
SCN3A [HSA:6328] [KO:K04836]
SCN4A [HSA:6329] [KO:K04837]
SCN5A [HSA:6331] [KO:K04838]
SCN8A [HSA:6334] [KO:K04840]
SCN9A [HSA:6335] [KO:K04841]
SCN10A [HSA:6336] [KO:K04842]
SCN11A [HSA:11280] [KO:K04843]
  Pathway
hsa04728  Dopaminergic synapse
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N01 ANESTHETICS
   N01B ANESTHETICS, LOCAL
    N01BA Esters of aminobenzoic acid
     N01BA04 Chloroprocaine
      D00732  Chloroprocaine hydrochloride (USP) <US>
Target-based classification of drugs [BR:br08310]
 Ion channels
  Voltage-gated ion channels
   Sodium channels
    SCN1A
     D00732  Chloroprocaine hydrochloride (USP) <US>
    SCN2A
     D00732  Chloroprocaine hydrochloride (USP) <US>
    SCN3A
     D00732  Chloroprocaine hydrochloride (USP) <US>
    SCN4A
     D00732  Chloroprocaine hydrochloride (USP) <US>
    SCN5A
     D00732  Chloroprocaine hydrochloride (USP) <US>
    SCN8A
     D00732  Chloroprocaine hydrochloride (USP) <US>
    SCN9A
     D00732  Chloroprocaine hydrochloride (USP) <US>
    SCN10A
     D00732  Chloroprocaine hydrochloride (USP) <US>
    SCN11A
     D00732  Chloroprocaine hydrochloride (USP) <US>
BRITE hierarchy
Other DBs
CAS: 3858-89-7
PubChem: 7847797
ChEBI: 3637
ChEMBL: CHEMBL944
DrugBank: DB01161
LigandBox: D00732
NIKKAJI: J383.182E
LinkDB All DBs
KCF data Show

ATOM        19
            1   C8y C    18.6136  -14.8634
            2   C8y C    18.6136  -13.4572
            3   C7a C    19.8213  -15.5576
            4   C8x C    17.3999  -15.5576
            5   C8x C    17.3999  -12.7511
            6   X   Cl   19.8213  -12.7511
            7   O7a O    21.0350  -14.8691
            8   O6a O    19.8155  -16.9639
            9   C8x C    16.1863  -14.8634
            10  C8y C    16.1863  -13.4572
            11  C1b C    22.2428  -15.5693
            12  N1a N    14.9669  -12.7628
            13  C1b C    23.4564  -14.8750
            14  N1c N    24.6701  -15.5752
            15  C1b C    25.8780  -14.8808
            16  C1b C    24.6701  -16.9697
            17  C1a C    27.0915  -15.5810
            18  C1a C    25.8780  -17.6815
            19  X   Cl   25.2536  -12.9728
BOND        18
            1     1   2 1
            2     1   3 1
            3     1   4 2
            4     2   5 2
            5     2   6 1
            6     3   7 1
            7     3   8 2
            8     4   9 1
            9     5  10 1
            10    7  11 1
            11   10  12 1
            12   11  13 1
            13   13  14 1
            14   14  15 1
            15   14  16 1
            16   15  17 1
            17   16  18 1
            18    9  10 2

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