| Entry |
|
|---|
| Name |
Desipramine hydrochloride (JAN/USP);
Norpramin (TN) |
|---|
| Product |
|
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| Generic |
DESIPRAMINE HYDROCHLORIDE (Amneal Pharmaceuticals NY LLC), DESIPRAMINE HYDROCHLORIDE (Bryant Ranch Prepack), DESIPRAMINE HYDROCHLORIDE (Actavis Pharma), DESIPRAMINE HYDROCHLORIDE (Alembic Pharmaceuticals), DESIPRAMINE HYDROCHLORIDE (Alembic Pharmaceuticals Limited), DESIPRAMINE HYDROCHLORIDE (Bryant Ranch Prepack), DESIPRAMINE HYDROCHLORIDE (Bryant Ranch Prepack), DESIPRAMINE HYDROCHLORIDE (DIRECT RX), DESIPRAMINE HYDROCHLORIDE (Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals), DESIPRAMINE HYDROCHLORIDE (Ingenus Pharmaceuticals), DESIPRAMINE HYDROCHLORIDE (Preferred Pharmaceuticals), DESIPRAMINE HYDROCHLORIDE (Sandoz) |
|---|
| Formula |
C18H22N2. HCl
|
|---|
| Exact mass |
302.155
|
|---|
| Mol weight |
302.8416
|
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| Structure |
|
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| Simcomp |
|
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| Class |
Neuropsychiatric agent
DG01730 Non-selective monoamine reuptake inhibitor
DG01728 Tricyclic antidepressant
|
|---|
| Remark |
| Product (DG00927): | D00812<US> |
|
|---|
| Efficacy |
Antidepressant, Serotonin-noradrenaline reuptake inhibitor (SNRI) |
|---|
| Disease |
|
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| Target |
|
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| Pathway |
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| Interaction |
|
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| Structure map |
| map07234 | Neurotransmitter transporter inhibitors |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N06 PSYCHOANALEPTICS
N06A ANTIDEPRESSANTS
N06AA Non-selective monoamine reuptake inhibitors
N06AA01 Desipramine
D00812 Desipramine hydrochloride (JAN/USP) <US>
USP drug classification [BR:br08302]
Antidepressants
Tricyclics
Desipramine
D00812 Desipramine hydrochloride (JAN/USP)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01730 Non-selective monoamine reuptake inhibitor
DG00927 Desipramine
D00812 Desipramine hydrochloride
DG01728 Tricyclic antidepressant
DG00927 Desipramine
D00812 Desipramine hydrochloride
Drug classes [BR:br08332]
Neuropsychiatric agent
DG01730 Non-selective monoamine reuptake inhibitor
D00812 Desipramine hydrochloride
Target-based classification of drugs [BR:br08310]
Transporters
Solute carrier family
SLC6
SLC6A2 (NAT1)
D00812 Desipramine hydrochloride (JAN/USP) <US>
SLC6A4 (HTT)
D00812 Desipramine hydrochloride (JAN/USP) <US>
Pharmacogenomic biomarkers [br08341.html]
Polymorphisms and mutations affecting drug response
D00812
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01730 Non-selective monoamine reuptake inhibitor
DG00927 Desipramine
DG01728 Tricyclic antidepressant
DG00927 Desipramine
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 21
1 C1x C 12.5108 -18.1831
2 C8y C 11.6661 -17.0701
3 C8y C 12.0023 -15.7092
4 N1y N 13.2672 -15.1293
5 C1x C 13.9209 -18.2084
6 C8y C 14.5246 -15.7535
7 C8y C 14.8120 -17.1264
8 C8x C 10.9921 -14.7378
9 C8x C 9.6460 -15.1271
10 C8x C 9.3098 -16.4880
11 C8x C 10.3200 -17.4591
12 C8x C 16.1472 -17.5648
13 C8x C 17.1946 -16.6276
14 C8x C 16.9074 -15.2547
15 C8x C 15.5719 -14.8162
16 C1b C 13.2889 -13.7502
17 C1b C 14.5167 -13.0670
18 C1b C 15.6886 -13.7686
19 N1b N 16.9145 -13.0865
20 C1a C 18.1530 -13.8273
21 X Cl 20.1707 -16.3481
BOND 22
1 3 4 1
2 1 5 1
3 4 6 1
4 2 3 1
5 5 7 1
6 1 2 1
7 6 7 1
8 3 8 2
9 8 9 1
10 9 10 2
11 10 11 1
12 2 11 2
13 7 12 2
14 12 13 1
15 13 14 2
16 14 15 1
17 6 15 2
18 4 16 1
19 16 17 1
20 17 18 1
21 18 19 1
22 19 20 1
|
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