KEGG   DRUG: Hydrocodone bitartrate and acetaminophen
Entry
D00846            Mixture   Drug                                   
Name
Hydrocodone bitartrate and acetaminophen;
Hydrocodone bitartrate and paracetamol;
Vicodin (TN)
Product
  Generic
HYDROCODONE /APAP (DIRECTRX), HYDROCODONE /APAP (Direct_Rx), HYDROCODONE /APAP (Direct_Rx), HYDROCODONE /APAP (Direct_Rx), HYDROCODONE /APAP (Direct_Rx), HYDROCODONE /APAP (Direct_Rx), HYDROCODONE APAP (Direct_Rx), HYDROCODONE BITARTRATE (DIRECT RX), HYDROCODONE BITARTRATE (DIRECT RX), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (A-S Medication Solutions), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (A-S Medication Solutions), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (American Health Packaging), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (American Health Packaging), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (American Health Packaging), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Amneal Pharmaceuticals LLC), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Amneal Pharmaceuticals LLC), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Amneal Pharmaceuticals LLC), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Amneal Pharmaceuticals of New York LLC), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Amneal Pharmaceuticals of New York LLC), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Asclemed USA), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Asclemed USA), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Asclemed USA), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Aurolife Pharma), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Aurolife Pharma), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (AvPAK), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (AvPAK), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Bryant Ranch Prepack), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Camber Pharmaceuticals), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Camber Pharmaceuticals), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Direct Rx), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (DirectRx), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (DirectRx), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Direct_Rx), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Direct_Rx), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Direct_Rx), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Elite Laboratories), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Epic Pharma), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Eywa Pharma), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Eywa Pharma), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Eywa Pharma), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Genus Lifesciences), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Genus Lifesciences), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Genus Lifesciences), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Golden State Medical Supply), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Granules Pharmaceuticals), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (KVK-Tech), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Lake Erie Medical DBA Quality Care Products LLC), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Lake Erie Medical DBA Quality Care Products LLC), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Lannett Company), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Lannett Company), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Lupin Pharmaceuticals), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Lupin Pharmaceuticals), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Major Pharmaceuticals), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Medsource Pharmaceticals), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Northwind Pharmaceuticals), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Northwind Pharmaceuticals), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Novel Laboratories), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Novel Laboratories), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (NuCare Pharmaceuticals), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (NuCare Pharmaceuticals), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (NuCare Pharmaceuticals), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (NuCare Pharmaceuticals), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (NuCare Pharmaceuticals), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (NuCare Pharmaceuticals), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (NuCare Pharmaceuticals), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (NuCare Pharmaceuticals), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (NuCare Pharmaceuticals), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (NuCare Pharmaceuticals), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (NuCare Pharmaceuticals), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (NuCare Pharmaceuticals), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (PAI Holdings), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Par Pharmaceutical), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Proficient Rx LP), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Proficient Rx LP), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Proficient Rx LP), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Proficient Rx LP), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Proficient Rx LP), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Proficient Rx LP), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Proficient Rx LP), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Proficient Rx LP), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Proficient Rx LP), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Proficient Rx LP), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Quality Care Products), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Quality Care Products), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Quality Care Products), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Quality Care Products), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (REMEDYREPACK), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (RedPharm Drug), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (RedPharm Drug), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (RedPharm Drug), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (RedPharm Drug), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (RedPharm Drug), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (RedPharm Drug), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (RedPharm Drug), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (RedPharm Drug), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (RedPharm Drug), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (RedPharm Drug), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (RedPharm Drug), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Redpharm Drug), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Redpharm Drug), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Redpharm Drug), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Redpharm drug), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Redpharm drug), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Rhodes Pharmaceuticals L.P.), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (SpecGx LLC), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (SpecGx LLC), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Sun Pharmaceutical Industries), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Tris Pharma), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Tris Pharma), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Tris Pharma), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Tris Pharma), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (Upsher-Smith Laboratories), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (VistaPharm), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (XLCare Pharmaceuticals), HYDROCODONE BITARTRATE AND ACETAMINOPHEN (XLCare Pharmaceuticals), HYDROCODONE/APAP (Direct_Rx), HYDROCODONE/APAP (Direct_Rx), NORCO (Direct_Rx)
Formula
C18H21NO3. C8H9NO2. C4H6O6
Exact mass
600.2319
Mol weight
600.61
Structure
Component
Hydrocodone bitartrate [DR:D03725], Acetaminophen [DR:D00217]
Remark
ATC code: N02AJ22
Product: D00846<US>
Efficacy
Analgesic
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N02 ANALGESICS
   N02A OPIOIDS
    N02AJ Opioids in combination with non-opioid analgesics
     N02AJ22 Hydrocodone and paracetamol
      D00846  Hydrocodone bitartrate and acetaminophen <US>
USP drug classification [BR:br08302]
 Analgesics
  Analgesics Combinations
   Acetaminophen/ Hydrocodone Bitartrate
    D00846  Hydrocodone bitartrate and acetaminophen
Other DBs
CAS: 330988-71-1
PubChem: 7847911
ChEBI: 5780
LigandBox: D00846
LinkDB
KCF data

ATOM        43
            1   C8y C    35.6036  -11.9087
            2   C8x C    35.6036  -13.3162
            3   C8x C    34.3890  -11.2139
            4   N1b N    36.8183  -11.2139
            5   C8x C    34.3890  -14.0227
            6   C8x C    33.1685  -11.9087
            7   C5a C    38.0388  -11.9146
            8   C8y C    33.1685  -13.3162
            9   C1a C    39.2605  -11.2139
            10  O5a O    38.0329  -13.3162
            11  O1a O    31.9538  -14.0227
            12  C1z C    24.9900  -15.0500
            13  C8y C    24.9900  -13.7200
            14  C1y C    26.1800  -15.7500
            15  C1y C    23.8700  -15.6800
            16  C1x C    26.1800  -14.4200
            17  C8y C    23.8700  -13.0900
            18  C8y C    26.1800  -13.0900
            19  C1y C    27.3000  -15.0500
            20  C1x C    26.1800  -17.0100
            21  O2x O    22.6100  -14.3500
            22  C5x C    23.8700  -17.0100
            23  C1x C    28.4200  -14.4200
            24  C8y C    23.8700  -11.7600
            25  C1x C    27.3000  -13.7900
            26  C8x C    26.1800  -11.7600
            27  N1y N    28.4200  -15.7500
            28  C1x C    24.9900  -17.7100
            29  O5x O    22.8200  -17.7100
            30  C8x C    25.0600  -11.1300
            31  O2a O    22.8200  -11.1300
            32  C1a C    21.6300  -11.7600
            33  C1a C    29.8200  -15.7500
            34  O6a O    33.2031  -16.1006
            35  C6a C    34.4156  -16.8006
            36  C1c C    35.6281  -16.1006
            37  C1c C    36.8405  -16.8006
            38  C6a C    38.0531  -16.1006
            39  O6a O    39.2655  -16.8006
            40  O6a O    34.4156  -18.2005
            41  O1a O    35.6281  -14.7005
            42  O1a O    36.8405  -18.2006
            43  O6a O    38.0531  -14.7008
BOND        46
            1     7   9 1
            2     7  10 2
            3     8  11 1
            4     6   8 2
            5     1   2 1
            6     1   3 2
            7     1   4 1
            8     2   5 2
            9     3   6 1
            10    4   7 1
            11    5   8 1
            12   12  13 1
            13   12  14 1
            14   12  15 1
            15   12  16 1 #Up
            16   13  17 2
            17   13  18 1
            18   14  19 1
            19   14  20 1
            20   15  21 1 #Down
            21   15  22 1
            22   16  23 1
            23   17  24 1
            24   18  25 1
            25   18  26 2
            26   19  27 1 #Up
            27   20  28 1
            28   22  29 2
            29   24  30 2
            30   24  31 1
            31   31  32 1
            32   17  21 1
            33   19  25 1
            34   22  28 1
            35   23  27 1
            36   26  30 1
            37   27  33 1
            38   34  35 1
            39   35  36 1
            40   36  37 1
            41   37  38 1
            42   38  39 1
            43   35  40 2
            44   36  41 1 #Down
            45   37  42 1 #Down
            46   38  43 2

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