KEGG   DRUG: Sulconazole nitrateHelp
Entry
D00886                      Drug                                   

Name
Sulconazole nitrate (JAN/USP);
Exelderm (TN)
Product
Formula
C18H15Cl3N2S. HNO3
Exact mass
458.9978
Mol weight
460.7619
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Antifungal
 DG01883  Imidazole antifungal
Remark
Therapeutic category: 2655
ATC code: D01AC09
Chemical structure group: DG00366
Product (DG00366): D00886<JP/US>
Efficacy
Antifungal, Ergosterol biosynthesis inhibitor
  Disease
Tinea pedis [DS:H01316]
Tinea versicolor [DS:H01334]
Comment
Imidazole derivative
Target
sterol 14alpha-demethylase [KO:K05917]
  Pathway
ko00100  Steroid biosynthesis
Interaction
Drug interaction
Structure map
map07026  Antifungal agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 D DERMATOLOGICALS
  D01 ANTIFUNGALS FOR DERMATOLOGICAL USE
   D01A ANTIFUNGALS FOR TOPICAL USE
    D01AC Imidazole and triazole derivatives
     D01AC09 Sulconazole
      D00886  Sulconazole nitrate (JAN/USP) <JP/US>
USP drug classification [BR:br08302]
 Antifungals
  Sulconazole
   D00886  Sulconazole nitrate (JAN/USP)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  26  Epidermides
   265  Antiparasitic dermatosis agents
    2655  Imidazoles
     D00886  Sulconazole nitrate (JAN/USP)
Classification of Japanese OTC drugs [BR:br08313]
 Agents for integumentary system
  58 Ringworm drugs
   D00886  Sulconazole nitrate (JAN/USP)
Risk category of Japanese OTC drugs [BR:br08312]
 Second-class OTC drugs
  Inorganic and organic chemicals
   Sulconazole
    D00886  Sulconazole nitrate (JAN/USP)
Antiinfectives [br08350.html]
 Antifungals
  D00886
Rx-to-OTC switch list in Japan [br08314.html]
 D00886
BRITE hierarchy
Other DBs
CAS: 61318-91-0
PubChem: 7847950
ChEBI: 9326
ChEMBL: CHEMBL1200348
LigandBox: D00886
NIKKAJI: J364.821D
LinkDB All DBs
KCF data Show

ATOM        28
            1   N2b N    39.2735  -20.6975 #+
            2   O3a O    39.2676  -19.3000
            3   O3a O    40.4959  -21.3962 #-
            4   O1b O    38.0517  -21.4097
            5   C8y C    26.0400  -14.4900
            6   C8x C    26.0400  -15.8900
            7   C8x C    27.2524  -16.5900
            8   C8y C    28.4649  -15.8900
            9   C8x C    28.4649  -14.4900
            10  C8x C    27.2524  -13.7900
            11  X   Cl   24.8276  -13.7900
            12  C1b C    29.6960  -16.6010
            13  S2a S    30.9012  -15.9053
            14  C1c C    32.0835  -16.5881
            15  C1b C    33.2775  -15.8988
            16  C8y C    32.0835  -17.9898
            17  N4y N    34.4654  -16.5848
            18  C8x C    34.8840  -17.9125
            19  C8y C    30.8535  -18.7001
            20  C8x C    30.8536  -20.1001
            21  C8y C    32.0661  -20.8000
            22  C8x C    33.2961  -20.0897
            23  C8x C    33.2960  -18.6897
            24  N5x N    36.2839  -17.9244
            25  C8x C    36.7278  -16.5966
            26  C8x C    35.6023  -15.7642
            27  X   Cl   29.6491  -18.0048
            28  X   Cl   32.0662  -22.1900
BOND        29
            1     1   2 2
            2     1   3 1
            3     1   4 1
            4     5   6 2
            5     6   7 1
            6     7   8 2
            7     8   9 1
            8     9  10 2
            9     5  10 1
            10    5  11 1
            11    8  12 1
            12   12  13 1
            13   13  14 1
            14   14  15 1
            15   14  16 1
            16   15  17 1
            17   17  18 1
            18   16  19 2
            19   19  20 1
            20   20  21 2
            21   21  22 1
            22   22  23 2
            23   16  23 1
            24   18  24 2
            25   24  25 1
            26   25  26 2
            27   17  26 1
            28   19  27 1
            29   21  28 1

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