| Entry |
|
|---|
| Name |
Ambenonium chloride (JP18/INN);
Mytelase (TN) |
|---|
| Formula |
C28H42Cl2N4O2. 2Cl
|
|---|
| Exact mass |
606.2062
|
|---|
| Mol weight |
608.46
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01595 Cholinesterase inhibitor
DG01593 Acetylcholinesterase inhibitor
DG01719 Parasympathomimetic agent
|
|---|
| Remark |
| Therapeutic category: | 1231 |
| Product (DG00990): | D01001<JP> |
|
|---|
| Efficacy |
Acetylcholinesterase inhibitor |
|---|
| Comment |
Quaternary ammonium compound
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07220 | Cholinergic and anticholinergic drugs |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N07 OTHER NERVOUS SYSTEM DRUGS
N07A PARASYMPATHOMIMETICS
N07AA Anticholinesterases
N07AA30 Ambenonium
D01001 Ambenonium chloride (JP18/INN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
12 Agents affecting peripheral nervous system
123 Autonomic nervous system agents
1231 Quaternary ammoniums
D01001 Ambenonium chloride (JP18/INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01595 Cholinesterase inhibitor
DG01593 Acetylcholinesterase inhibitor
DG00990 Ambenonium
D01001 Ambenonium chloride
DG01719 Parasympathomimetic agent
DG00990 Ambenonium
D01001 Ambenonium chloride
Target-based classification of drugs [BR:br08310]
Enzymes
Hydrolases (EC3)
Carboxylic-ester hydrolases
ACHE
D01001 Ambenonium chloride (JP18/INN) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D01001 Ambenonium chloride
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01595 Cholinesterase inhibitor
DG01593 Acetylcholinesterase inhibitor
DG00990 Ambenonium
DG01719 Parasympathomimetic agent
DG00990 Ambenonium
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 38
1 X Cl 27.0752 -15.2685 #-
2 X Cl 19.4424 -20.2555 #-
3 N1d N 18.0129 -18.3284 #+
4 C1b C 16.8053 -17.6283
5 C1b C 19.2205 -17.6342
6 C1b C 18.0129 -19.7226
7 C1b C 17.9838 -16.9225
8 C8y C 15.5977 -18.3284
9 C1b C 20.4280 -18.3284
10 C1a C 16.8053 -20.4226
11 C1a C 19.1798 -16.1991
12 C8y C 14.3901 -17.6283
13 C8x C 15.5977 -19.7226
14 N1b N 21.6414 -17.6342
15 C8x C 13.1768 -18.3284
16 X Cl 14.3901 -16.2341
17 C8x C 14.3901 -20.4226
18 C5a C 22.8490 -18.3341
19 C8x C 13.1768 -19.7226
20 C5a C 24.0566 -17.6342
21 O5a O 22.8490 -19.7285
22 N1b N 25.2642 -18.3341
23 O5a O 24.0566 -16.2398
24 C1b C 26.4777 -17.6400
25 C1b C 27.6853 -18.3341
26 N1d N 28.8927 -17.6400 #+
27 C1b C 30.1003 -18.3400
28 C1b C 28.8927 -16.2458
29 C1b C 28.9220 -19.1159
30 C8y C 31.3079 -17.6400
31 C1a C 30.1003 -15.5457
32 C1a C 27.6560 -19.8801
33 C8y C 32.5098 -18.3458
34 C8x C 31.3022 -16.2515
35 C8x C 33.7174 -17.6459
36 X Cl 32.5038 -19.7402
37 C8x C 32.5098 -15.5515
38 C8x C 33.7174 -16.2515
BOND 37
1 3 4 1
2 3 5 1
3 3 6 1
4 3 7 1
5 4 8 1
6 5 9 1
7 6 10 1
8 7 11 1
9 8 12 2
10 8 13 1
11 9 14 1
12 12 15 1
13 12 16 1
14 13 17 2
15 14 18 1
16 15 19 2
17 18 20 1
18 18 21 2
19 20 22 1
20 20 23 2
21 22 24 1
22 24 25 1
23 25 26 1
24 26 27 1
25 26 28 1
26 26 29 1
27 27 30 1
28 28 31 1
29 29 32 1
30 30 33 2
31 30 34 1
32 33 35 1
33 33 36 1
34 34 37 2
35 35 38 2
36 17 19 1
37 37 38 1
|
|---|
