| Entry |
|
|---|
| Name |
Flupentixol (INN);
Flupenthixol;
Depixol (TN) |
|---|
| Formula |
C23H25F3N2OS
|
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| Exact mass |
434.1640
|
|---|
| Mol weight |
434.52
|
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| Structure |
|
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| Simcomp |
|
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| Class |
Neuropsychiatric agent
DG01478 Dopamine antagonist
|
|---|
| Remark |
|
|---|
| Efficacy |
Antipsychotic, Dopamine receptor antagonist |
|---|
| Comment |
Thioxanthene derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
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| Structure map |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N05 PSYCHOLEPTICS
N05A ANTIPSYCHOTICS
N05AF Thioxanthene derivatives
N05AF01 Flupentixol
D01044 Flupentixol (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG00893 Flupentixol
D01044 Flupentixol
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Dopamine
DRD1
D01044 Flupentixol (INN)
DRD2
D01044 Flupentixol (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG00893 Flupentixol
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 30
1 C8x C 14.5600 -19.8100
2 C8x C 14.5600 -21.2100
3 C8x C 15.8200 -21.9100
4 C8x C 15.8200 -19.1100
5 C8y C 16.9400 -19.8100
6 C8y C 16.9400 -21.2100
7 S2x S 18.2000 -21.9100
8 C8y C 18.2000 -19.1100
9 C8y C 19.3900 -19.8100
10 C8y C 19.3900 -21.2100
11 C8x C 20.5800 -21.9100
12 C8x C 21.8400 -21.2100
13 C8y C 21.8400 -19.8100
14 C8x C 20.5800 -19.1100
15 C2b C 18.2000 -17.7100
16 C1b C 19.4129 -17.0107
17 C1b C 19.4129 -15.6107
18 N1y N 20.6083 -14.9203
19 C1x C 21.7951 -15.6054
20 C1x C 23.0075 -14.9054
21 N1y N 23.0074 -13.5054
22 C1x C 21.8207 -12.8203
23 C1x C 20.6083 -13.5203
24 C1b C 24.2424 -12.8100
25 C1b C 25.4549 -13.5100
26 O1a O 26.6673 -12.8100
27 C1d C 23.0466 -19.1000
28 X F 24.2591 -18.4000
29 X F 22.3466 -17.8876
30 X F 23.7466 -20.3125
BOND 33
1 8 5 1
2 1 2 1
3 2 3 2
4 3 6 1
5 9 10 2
6 10 11 1
7 11 12 2
8 12 13 1
9 13 14 2
10 14 9 1
11 5 4 1
12 8 15 2
13 4 1 2
14 5 6 2
15 6 7 1
16 7 10 1
17 9 8 1
18 15 16 1
19 16 17 1
20 17 18 1
21 18 19 1
22 19 20 1
23 20 21 1
24 21 22 1
25 22 23 1
26 18 23 1
27 21 24 1
28 24 25 1
29 25 26 1
30 13 27 1
31 27 28 1
32 27 29 1
33 27 30 1
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