| Entry |
|
|---|
| Name |
Acetazolamide sodium (JAN);
Diamox (TN) |
|---|
| Product |
|
|---|
| Generic |
|
|---|
| Formula |
C4H5N4O3S2. Na
|
|---|
| Exact mass |
243.9701
|
|---|
| Mol weight |
244.23
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01534 Carbonic anhydrase inhibitor
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
|
|---|
| Remark |
| Therapeutic category: | 2134 |
| Product (DG01134): | D00218<JP/US> D01196<JP/US> |
|
|---|
| Efficacy |
Antiglaucoma, Carbonic anhydrase inhibitor |
|---|
| Disease |
Chronic simple (open-angle) glaucoma [DS: H00612] |
|---|
| Comment |
Sulfonamide derivative
Diuretic action
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04964 | Proximal tubule bicarbonate reclamation |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07017 | Sulfonamide derivatives - diuretics |
| map07055 | Sulfonamide derivatives - overview |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS
S01EC Carbonic anhydrase inhibitors
S01EC01 Acetazolamide
D01196 Acetazolamide sodium (JAN) <JP/US>
USP drug classification [BR:br08302]
Cardiovascular Agents
Cardiovascular Agents, Other
Acetazolamide
D01196 Acetazolamide sodium (JAN)
Ophthalmic Agents
Intraocular Pressure Lowering Agents
Carbonic Anhydrase Inhibitors, Ophthalmic
Acetazolamide
D01196 Acetazolamide sodium (JAN)
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
21 Cardiovascular agents
213 Diuretics
2134 Carbonic anhydrase inhibitors
D01196 Acetazolamide sodium (JAN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01534 Carbonic anhydrase inhibitor
DG01134 Acetazolamide
D01196 Acetazolamide sodium
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
DG01134 Acetazolamide
D01196 Acetazolamide sodium
Drug classes [BR:br08332]
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
D01196 Acetazolamide sodium
Target-based classification of drugs [BR:br08310]
Enzymes
Lyases (EC4)
Aldehyde-lyases
CA
D01196 Acetazolamide sodium (JAN) <JP/US>
Drug groups [BR:br08330]
Cardiovascular agent
DG01534 Carbonic anhydrase inhibitor
DG01134 Acetazolamide
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
DG01134 Acetazolamide
|
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| Other DBs |
|
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| LinkDB |
|
|---|
| KCF data |
ATOM 14
1 N5x N 25.5209 -16.3791
2 C8y C 25.9582 -15.0505
3 S2x S 24.8212 -14.2224
4 C8y C 23.6844 -15.0505
5 N5x N 24.1217 -16.3791
6 N1b N 27.1654 -14.3451
7 C5a C 28.3702 -15.0373
8 C1a C 29.5819 -14.3378
9 O5a O 28.3733 -16.4368
10 S4a S 22.2790 -15.0465
11 O3c O 22.2790 -13.6470
12 O3c O 20.8795 -15.0465
13 N1a N 22.2790 -16.4461 #-
14 Z Na 19.6199 -17.1459 #+
BOND 13
1 6 7 1
2 1 2 2
3 7 8 1
4 2 3 1
5 7 9 2
6 3 4 1
7 4 5 2
8 5 1 1
9 2 6 1
10 4 10 1
11 10 11 2
12 10 12 2
13 10 13 1
|
|---|
