KEGG   DRUG: Terguride
Entry
D01348                      Drug                                   
Name
Terguride (JAN/INN);
Teluron (TN)
Formula
C20H28N4O
Exact mass
340.2263
Mol weight
340.46
Structure
Simcomp
Class
Neuropsychiatric agent
 DG01472  Dopamine agonist
  DG01468  Dopamine D2-receptor agonist
 DG01964  Ergot alkaloid
Remark
ATC code: G02CB06
Efficacy
Antihyperprolactinemia, Dopamine D2 receptor agonist, Prolactin inhibitor
Target
DRD2 [HSA:1813] [KO:K04145]
PRL [HSA:5617] [KO:K05439]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04728  Dopaminergic synapse
hsa04917  Prolactin signaling pathway
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 G GENITO URINARY SYSTEM AND SEX HORMONES
  G02 OTHER GYNECOLOGICALS
   G02C OTHER GYNECOLOGICALS
    G02CB Prolactine inhibitors
     G02CB06 Terguride
      D01348  Terguride (JAN/INN)
Drug groups [BR:br08330]
 Neuropsychiatric agent
  DG01472  Dopamine agonist
   DG01468  Dopamine D2-receptor agonist
    D01348  Terguride
  DG01964  Ergot alkaloid
   D01348  Terguride
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Dopamine
    DRD2
     D01348  Terguride (JAN/INN)
 Cytokines and receptors
  Cytokines
   CSF and other factors
    PRL
     D01348  Terguride (JAN/INN)
Other DBs
CAS: 37686-84-3
PubChem: 7848411
ChEBI: 32193
LigandBox: D01348
NIKKAJI: J32.502C
LinkDB
KCF data

ATOM        25
            1   C8x C    21.4545  -21.8126
            2   C8x C    22.5843  -19.7253
            3   C8x C    21.4181  -20.4396
            4   C8y C    23.7901  -20.3779
            5   C1x C    26.1908  -21.6881
            6   C1y C    24.9576  -19.6660
            7   C1y C    26.1496  -20.3233
            8   N1y N    27.3149  -19.6195
            9   C1x C    27.2881  -18.2586
            10  C1y C    26.0959  -17.6012
            11  C1x C    25.0006  -18.3049
            12  C1a C    28.5156  -20.2816
            13  N1b N    26.0690  -16.2305
            14  C5a C    27.2426  -15.5217
            15  N1c N    27.2155  -14.1510
            16  O5a O    28.4431  -16.1836
            17  C1b C    28.3891  -13.4422
            18  C1b C    26.0150  -13.4889
            19  C1a C    26.0579  -12.1182
            20  C1a C    28.4322  -12.0713
            21  C8y C    23.8207  -21.7430
            22  C8y C    22.6625  -22.4578
            23  C8y C    25.0189  -22.3886
            24  N4x N    22.6554  -23.8240
            25  C8x C    25.0097  -23.8248
BOND        28
            1     8  12 1
            2     5   7 1
            3    10  13 1 #Down
            4     6   4 1
            5    13  14 1
            6     4   2 1
            7    14  15 1
            8     2   3 2
            9    14  16 2
            10    3   1 1
            11   15  17 1
            12   15  18 1
            13    1  22 2
            14   18  19 1
            15    4  21 2
            16   17  20 1
            17    6   7 1
            18    7   8 1
            19    8   9 1
            20    9  10 1
            21   10  11 1
            22   21  22 1
            23   23  21 1
            24   11   6 1
            25   22  24 1
            26   23   5 1
            27   23  25 2
            28   24  25 1

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