| Entry |
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| Name |
Retinol acetate (JP17) |
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| Formula |
C22H32O2
|
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| Exact mass |
328.2402
|
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| Mol weight |
328.4883
|
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| Structure |
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| Simcomp |
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| Class |
Other
DG01604 Retinol derivative
Metabolizing enzyme substrate
DG02918 CYP2C8 substrate
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| Remark |
| Product (DG00123): | D06543<JP> D00164<JP/US> |
|
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| Efficacy |
Anti-acne, Supplement (vitamin A), Retinoic acid receptor (RAR) agonist |
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| Target |
|
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| Metabolism |
Enzyme: CYP2C8 [HSA: 1558]
|
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| Interaction |
|
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| Structure map |
| map07223 | Retinoic acid receptor (RAR) and retinoid X receptor (RXR) agonists/antagonists |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A11 VITAMINS
A11C VITAMIN A AND D, INCL. COMBINATIONS OF THE TWO
A11CA Vitamin A, plain
A11CA01 Retinol (vit A)
D01621 Retinol acetate (JP17)
D DERMATOLOGICALS
D10 ANTI-ACNE PREPARATIONS
D10A ANTI-ACNE PREPARATIONS FOR TOPICAL USE
D10AD Retinoids for topical use in acne
D10AD02 Retinol
D01621 Retinol acetate (JP17)
R RESPIRATORY SYSTEM
R01 NASAL PREPARATIONS
R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
R01AX Other nasal preparations
R01AX02 Retinol
D01621 Retinol acetate (JP17)
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01X OTHER OPHTHALMOLOGICALS
S01XA Other ophthalmologicals
S01XA02 Retinol
D01621 Retinol acetate (JP17)
Risk category of Japanese OTC drugs [BR:br08312]
Designated second-class OTC drugs
Inorganic and organic chemicals
Retinol acetate
D01621 Retinol acetate (JP17)
Second-class OTC drugs
Inorganic and organic chemicals
Retinol acetate
D01621 Retinol acetate (JP17)
Third-class OTC drugs
Inorganic and organic chemicals
Retinol acetate
D01621 Retinol acetate (JP17)
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Thyroid hormone like receptors
Retinoic acid receptor (RAR)
NR1B (RAR)
D01621 Retinol acetate (JP17)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D01621 Retinol acetate
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D01621
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 24
1 C1x C 24.8655 -17.1513
2 C1x C 24.8655 -18.5602
3 C1x C 26.0856 -19.2646
4 C2y C 27.3057 -18.5602
5 C2y C 27.3057 -17.1513
6 C1z C 26.0856 -16.4469
7 C1a C 28.5258 -19.2646
8 C2b C 29.7459 -17.1513
9 C2b C 28.5258 -16.4469
10 C2c C 30.9511 -16.4554
11 C2b C 32.1469 -17.1458
12 C2b C 33.3453 -16.4538
13 C1a C 30.9512 -15.0384
14 C2b C 34.5424 -17.1450
15 C2c C 35.7400 -16.4534
16 C2b C 36.9377 -17.1448
17 C1b C 38.1351 -16.4532
18 O7a O 39.3328 -17.1448
19 C1a C 35.7401 -15.0383
20 C7a C 40.5484 -16.4431
21 C1a C 41.7499 -17.1370
22 O6a O 40.5485 -15.0501
23 C1a C 27.0756 -15.4570
24 C1a C 25.0957 -15.4570
BOND 24
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 2
5 5 6 1
6 1 6 1
7 4 7 1
8 8 9 2
9 5 9 1
10 8 10 1
11 10 11 2
12 11 12 1
13 10 13 1
14 12 14 2
15 14 15 1
16 15 16 2
17 16 17 1
18 17 18 1
19 15 19 1
20 18 20 1
21 20 21 1
22 20 22 2
23 6 23 1
24 6 24 1
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