KEGG   DRUG: Ozagrel sodium
Entry
D01684                      Drug                                   

Name
Ozagrel sodium (JP17);
Ozapen (TN)
Formula
C13H11N2O2. Na
Exact mass
250.0718
Mol weight
250.2284
Structure
Simcomp
Class
Cardiovascular agent
 DG01712  Antiplatelet agent
  DG01516  Thromboxane A2 synthase inhibitor
 DG01950  Antithrombotic agent
  DG01712  Antiplatelet agent
   DG01516  Thromboxane A2 synthase inhibitor
 DG01516  Thromboxane A2 synthase inhibitor
Remark
Therapeutic category: 2190 3999
Chemical structure group: DG01256
Product (DG01256): D01683<JP> D01684<JP>
Efficacy
Anticoagulant, Platelet aggregation inhibitor, Thromboxane A2 (TXA2) synthase inhibitor
Target
TBXAS1 (CYP5A1) [HSA:6916] [KO:K01832]
  Pathway
hsa00590  Arachidonic acid metabolism
hsa04611  Platelet activation
Interaction
Structure map
map07034  Eicosanoids
map07049  Antithrombosis agents
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   219  Miscellaneous
    2190  Miscellaneous
     D01684  Ozagrel sodium (JP17)
 3  Agents affecting metabolism
  39  Other agents affecting metabolism
   399  Miscellaneous
    3999  Others
     D01684  Ozagrel sodium (JP17)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Isomerases (EC5)
   Thromboxane-A synthase
    TBXAS1 (CYP5A1)
     D01684  Ozagrel sodium (JP17) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01684  Ozagrel sodium
  D01684  Ozagrel sodium injection
  D01684  Ozagrel sodium for injection
Other DBs
CAS: 189224-26-8
PubChem: 7848747
LigandBox: D01684
NIKKAJI: J195.867D
LinkDB
KCF data

ATOM        18
            1   N4y N    27.0331  -14.7865
            2   C8x C    27.4703  -16.1159
            3   C8x C    28.1700  -13.9527
            4   C1b C    25.8087  -14.0985
            5   N5x N    28.8697  -16.1159
            6   C8x C    29.3070  -14.7865
            7   C8y C    24.6075  -14.8216
            8   C8x C    24.6308  -16.2266
            9   C8x C    23.3772  -14.1393
            10  C8x C    23.4238  -16.9439
            11  C8x C    22.2229  -14.8155
            12  C8y C    22.2112  -16.2617
            13  C2b C    21.0042  -16.9788
            14  C2b C    19.7876  -16.2963
            15  C6a C    18.5882  -17.0089
            16  O6a O    17.3715  -16.3266 #-
            17  O6a O    18.6057  -18.4039
            18  Z   Na   14.9549  -16.2803 #+
BOND        18
            1     2   5 2
            2     3   6 2
            3     4   7 1
            4     7   8 2
            5     7   9 1
            6     8  10 1
            7     9  11 2
            8    10  12 2
            9    12  13 1
            10    5   6 1
            11   11  12 1
            12   13  14 2
            13   14  15 1
            14    1   2 1
            15   15  16 1
            16    1   3 1
            17   15  17 2
            18    1   4 1

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