KEGG   DRUG: Oxprenolol hydrochloride
Entry
D01806                      Drug                                   

Name
Oxprenolol hydrochloride (JP17/USP);
Okuspurecol (TN)
Formula
C15H23NO3. HCl
Exact mass
301.1445
Mol weight
301.809
Structure
Simcomp
Class
Cardiovascular agent
 DG01653  Antiarrhythmics
  DG01806  Class II antiarrhythmic agent
 DG01466  Adrenergic receptor antagonist
  DG01464  beta-Adrenergic receptor antagonist
   DG01461  beta1-Adrenergic receptor antagonist
   DG01462  beta2-Adrenergic receptor antagonist
   DG01463  beta3-Adrenergic receptor antagonist
Remark
ATC code: C07AA02
Chemical structure group: DG00304
Efficacy
Antiarrhythmic, Vasodilator, beta-Adrenergic receptor antagonist
Comment
Propranolol derivative
Target
ADRB [HSA:153 154 155] [KO:K04141 K04142 K04143]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04261  Adrenergic signaling in cardiomyocytes
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C07 BETA BLOCKING AGENTS
   C07A BETA BLOCKING AGENTS
    C07AA Beta blocking agents, non-selective
     C07AA02 Oxprenolol
      D01806  Oxprenolol hydrochloride (JP17/USP)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    ADRB
     D01806  Oxprenolol hydrochloride (JP17/USP)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01806  Oxprenolol hydrochloride
Other DBs
CAS: 6452-73-9
PubChem: 7848868
ChEBI: 31949
ChEMBL: CHEMBL1200745
LigandBox: D01806
NIKKAJI: J369.034B
LinkDB
KCF data

ATOM        20
            1   X   Cl   18.2097  -28.2160
            2   O2a O    11.6200  -24.2200
            3   C1b C    12.8100  -23.5200
            4   C1c C    14.0700  -24.2200
            5   C1b C    15.2600  -23.5200
            6   N1b N    16.4500  -24.2200
            7   C1c C    17.7100  -23.5200
            8   C1a C    18.9000  -24.2200
            9   O1a O    14.0700  -25.6200
            10  C1a C    17.7100  -22.1200
            11  C8y C    11.6200  -25.6200
            12  C8y C    10.4076  -26.3200
            13  C8x C    10.4076  -27.7200
            14  C8x C    11.6200  -28.4200
            15  C8x C    12.8324  -27.7200
            16  C8x C    12.8324  -26.3200
            17  O2a O     9.2121  -25.6296
            18  C1b C     8.0247  -26.3151
            19  C2b C     6.8335  -25.6271
            20  C2a C     5.6440  -26.3138
BOND        19
            1     4   5 1
            2     5   6 1
            3     6   7 1
            4     7   8 1
            5     4   9 1
            6     7  10 1
            7     2   3 1
            8     3   4 1
            9     2  11 1
            10   11  12 2
            11   12  13 1
            12   13  14 2
            13   14  15 1
            14   15  16 2
            15   11  16 1
            16   12  17 1
            17   17  18 1
            18   18  19 1
            19   19  20 2

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