KEGG   DRUG: Felbinac ethyl
Entry
D01841                      Drug                                   

Name
Felbinac ethyl (JAN);
LM 001
Formula
C16H16O2
Exact mass
240.115
Mol weight
240.297
Structure
Simcomp
Class
Anti-inflammatory
 DG01906  Anti-inflammatory drug, acetic acid derivatives
  DG01898  Anti-inflammatory drug, phenylacetic acid derivatives
 DG01504  Nonsteroidal anti-inflammatory drug (NSAID)
  DG01906  Anti-inflammatory drug, acetic acid derivatives
   DG01898  Anti-inflammatory drug, phenylacetic acid derivatives
Remark
ATC code: M02AA08
Chemical structure group: DG00764
Product (DG00764): D01675<JP>
Efficacy
Analgesic, Anti-inflammatory, COX inhibitor
Comment
Phenylacetic acid derivative
Target
PTGS1 (COX1) [HSA:5742] [KO:K00509]
PTGS2 (COX2) [HSA:5743] [KO:K11987]
  Pathway
hsa00590  Arachidonic acid metabolism
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 M MUSCULO-SKELETAL SYSTEM
  M02 TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
   M02A TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
    M02AA Antiinflammatory preparations, non-steroids for topical use
     M02AA08 Felbinac
      D01841  Felbinac ethyl (JAN)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Oxidoreductases (EC1)
   Prostaglandin synthase
    PTGS1 (COX1)
     D01841  Felbinac ethyl (JAN)
    PTGS2 (COX2)
     D01841  Felbinac ethyl (JAN)
Other DBs
CAS: 14062-23-8
PubChem: 7848903
ChEBI: 31598
ChEMBL: CHEMBL1886408
LigandBox: D01841
NIKKAJI: J134.059J
LinkDB
KCF data

ATOM        18
            1   C8y C    26.6000  -24.4300
            2   C8x C    27.7900  -25.1300
            3   C8x C    26.6000  -23.0300
            4   C8x C    29.0500  -24.4300
            5   C8x C    27.7900  -22.3300
            6   C8y C    29.0500  -23.0300
            7   C1b C    30.2400  -22.3300
            8   C7a C    31.4300  -23.0300
            9   O6a O    31.4300  -24.4300
            10  O7a O    32.6900  -22.3300
            11  C1b C    33.8800  -23.0300
            12  C8y C    25.4100  -25.1300
            13  C8x C    24.1500  -24.4300
            14  C8x C    22.9600  -25.1300
            15  C8x C    22.9600  -26.5300
            16  C8x C    24.1500  -27.2300
            17  C8x C    25.4100  -26.5300
            18  C1a C    35.0700  -22.3300
BOND        19
            1     2   4 1
            2     3   5 2
            3     4   6 2
            4     6   7 1
            5     7   8 1
            6     8   9 2
            7     8  10 1
            8     5   6 1
            9    10  11 1
            10    1   2 2
            11    1   3 1
            12    1  12 1
            13   12  13 2
            14   13  14 1
            15   14  15 2
            16   15  16 1
            17   16  17 2
            18   12  17 1
            19   11  18 1

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