KEGG   DRUG: Carbutamide
Entry
D02425                      Drug                                   

Name
Carbutamide (INN);
Invenol (TN)
Formula
C11H17N3O3S
Exact mass
271.0991
Mol weight
271.336
Structure
Simcomp
Class
Antidiabetic agent
 DG01790  Sulfonamide hypoglycemic
  DG01734  Sulfonamide type sulfonylurea receptor agonist
 DG01508  Sulfonylurea receptor agonist
 DG02044  Hypoglycemics
  DG01790  Sulfonamide hypoglycemic
   DG01734  Sulfonamide type sulfonylurea receptor agonist
Remark
ATC code: A10BB06
Efficacy
Antidiabetic, Hypoglycemic, Sulfonylurea receptor agonist
Comment
Sulfonylurea
Target
ABCC8 (SUR1) [HSA:6833] [KO:K05032]
  Pathway
hsa02010  ABC transporters
hsa04911  Insulin secretion
hsa04930  Type II diabetes mellitus
Interaction
Structure map
map07018  Sulfonamide derivatives - hypoglycemic agents
map07055  Sulfonamide derivatives - overview
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A10 DRUGS USED IN DIABETES
   A10B BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
    A10BB Sulfonylureas
     A10BB06 Carbutamide
      D02425  Carbutamide (INN)
Target-based classification of drugs [BR:br08310]
 Transporters
  ABC transporters
   ABCC subfamily
    ABCC8 (SUR1)
     D02425  Carbutamide (INN)
Other DBs
CAS: 339-43-5
PubChem: 7849483
ChEMBL: CHEMBL448570
LigandBox: D02425
NIKKAJI: J5.684G
LinkDB
KCF data

ATOM        18
            1   C8y C    18.8472  -12.3307
            2   S4a S    20.0124  -11.6315
            3   C8x C    17.6354  -11.6315
            4   C8x C    18.8472  -13.6357
            5   N1b N    21.5505  -12.3773
            6   O3c O    20.8048  -10.4197
            7   O3c O    19.0336  -10.3731
            8   C8x C    16.4236  -12.2841
            9   C8x C    17.6354  -14.3815
            10  C5a C    22.6691  -11.6315
            11  C8y C    16.4236  -13.6824
            12  N1b N    23.8810  -12.2841
            13  O5a O    22.6691  -10.2799
            14  N1a N    15.2583  -14.3815
            15  C1b C    24.9996  -11.5383
            16  C1b C    26.1647  -12.2375
            17  C1b C    27.3766  -11.4917
            18  C1a C    28.4486  -12.0977
BOND        18
            1     1   2 1
            2     1   3 1
            3     1   4 2
            4     2   5 1
            5     2   6 2
            6     2   7 2
            7     3   8 2
            8     4   9 1
            9     5  10 1
            10    8  11 1
            11   10  12 1
            12   10  13 2
            13   11  14 1
            14   12  15 1
            15   15  16 1
            16   16  17 1
            17   17  18 1
            18    9  11 2

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