KEGG   DRUG: RifamycinHelp
Entry
D02549                      Drug                                   

Name
Rifamycin (USAN/INN);
Rifamycin SV
Product
Formula
C37H47NO12
Exact mass
697.3098
Mol weight
697.7686
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Sequence
0 Ahb  1 Mtn  2 Man  3 Mtd  4 Mtk  5 Mtk  6 Mtk  7 Mtk  8 Mtd
9 Mad  10 Mtn
  Type
PK
Source
Amycolatopsis mediterranei [TAX:33910]
Class
Antibacterial
 DG01598  Rifamycin antibiotic
 DG01966  Antitubercular
  DG01598  Rifamycin antibiotic
Remark
Same as: C12044
ATC code: A07AA13 D06AX15 J04AB03 S01AA16 S02AA12
Chemical structure group: DG00640
Product (DG00640): D02549<US>
Efficacy
Antibacterial (tuberculostatic)
Comment
Rifamycin derivative
Interaction
Drug interaction
Biosynthesis
map01051  Biosynthesis of ansamycins
Structure map
map07023  Rifamycins
map07114  Naphthalene family
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
   A07A INTESTINAL ANTIINFECTIVES
    A07AA Antibiotics
     A07AA13 Rifamycin
      D02549  Rifamycin (USAN/INN) <US>
 D DERMATOLOGICALS
  D06 ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE
   D06A ANTIBIOTICS FOR TOPICAL USE
    D06AX Other antibiotics for topical use
     D06AX15 Rifamycin
      D02549  Rifamycin (USAN/INN) <US>
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J04 ANTIMYCOBACTERIALS
   J04A DRUGS FOR TREATMENT OF TUBERCULOSIS
    J04AB Antibiotics
     J04AB03 Rifamycin
      D02549  Rifamycin (USAN/INN) <US>
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AA Antibiotics
     S01AA16 Rifamycin
      D02549  Rifamycin (USAN/INN) <US>
  S02 OTOLOGICALS
   S02A ANTIINFECTIVES
    S02AA Antiinfectives
     S02AA12 Rifamycin
      D02549  Rifamycin (USAN/INN) <US>
USP drug classification [BR:br08302]
 Gastrointestinal Agents
  Anti-Diarrheal Agents
   Rifamycin
    D02549  Rifamycin (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 6998-60-3
PubChem: 17396720
ChEBI: 29673
ChEMBL: CHEMBL4300133 CHEMBL437765
LigandBox: D02549
NIKKAJI: J8.871D
LinkDB All DBs
KCF data Show

ATOM        50
            1   C1c C    22.2618  -13.6612
            2   C1c C    22.2618  -15.0783
            3   O1a O    24.6237  -15.0109
            4   C1c C    24.6237  -13.6612
            5   C1c C    23.4090  -12.9864
            6   C2b C    26.9181  -13.6612
            7   C1c C    25.7709  -12.9864
            8   C5a C    28.1327  -15.7532
            9   C2c C    29.2800  -15.0783
            10  C2b C    29.2800  -13.6612
            11  C2b C    28.1327  -12.9864
            12  C1a C    25.7709  -11.6367
            13  C1a C    23.4090  -11.6367
            14  O1a O    21.1146  -12.9864
            15  C1a C    30.4272  -15.7532
            16  O5a O    26.9855  -15.0783
            17  N1b N    28.1327  -17.3728
            18  C1c C    21.1146  -15.7532
            19  O7a O    19.9674  -15.0783
            20  C1c C    21.1146  -17.3728
            21  C8y C    26.9855  -18.0476
            22  C8x C    26.9855  -19.3973
            23  C8y C    25.7709  -17.3728
            24  C8y C    24.6237  -18.0476
            25  C8y C    24.6237  -19.3973
            26  C8y C    25.7709  -20.0721
            27  C8y C    23.4764  -17.3728
            28  C8y C    22.2618  -18.0476
            29  C8y C    22.2618  -19.3973
            30  C8y C    23.4764  -20.0721
            31  O1a O    25.7709  -16.0231
            32  O1a O    23.4764  -16.0231
            33  C1a C    21.1146  -13.9987
            34  C7a C    18.7526  -14.4035
            35  C1a C    17.6054  -15.0783
            36  O6a O    18.7526  -13.0538
            37  C1c C    19.9674  -18.0476
            38  O2a O    18.8201  -17.3728
            39  C2b C    19.9674  -19.3973
            40  C1a C    19.9674  -16.4280
            41  C1a C    17.6729  -18.0476
            42  C2b C    18.8201  -20.0721
            43  O2a O    18.8201  -21.4218
            44  O2x O    21.1146  -20.0721
            45  C1z C    21.1146  -21.4218
            46  C5x C    23.4764  -21.4218
            47  C1a C    21.1146  -22.7714
            48  C1a C    22.2618  -16.6979
            49  O1a O    25.7709  -21.4218
            50  O5x O    24.5562  -22.0966
BOND        53
            1     1   2 1
            2     4   3 1 #Down
            3     4   5 1
            4     1   5 1
            5     6   7 1
            6     4   7 1
            7     8   9 1
            8     9  10 2
            9    10  11 1
            10    6  11 2
            11    7  12 1 #Up
            12    5  13 1 #Down
            13    1  14 1 #Down
            14    9  15 1
            15    8  16 2
            16    8  17 1
            17    2  18 1
            18   18  19 1 #Up
            19   18  20 1
            20   17  21 1
            21   21  22 1
            22   21  23 2
            23   23  24 1
            24   24  25 1
            25   25  26 1
            26   24  27 2
            27   27  28 1
            28   28  29 2
            29   29  30 1
            30   25  30 2
            31   23  31 1
            32   27  32 1
            33    2  33 1 #Up
            34   19  34 1
            35   34  35 1
            36   34  36 2
            37   26  22 2
            38   20  37 1
            39   37  38 1 #Down
            40   37  39 1
            41   20  40 1 #Down
            42   38  41 1
            43   39  42 2
            44   42  43 1
            45   29  44 1
            46   44  45 1
            47   43  45 1
            48   30  46 1
            49   45  46 1
            50   45  47 1 #Down
            51   28  48 1
            52   26  49 1
            53   50  46 2

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