KEGG   DRUG: Talampanel
Entry
D02696                      Drug                                   
Name
Talampanel (INN)
Formula
C19H19N3O3
Exact mass
337.1426
Mol weight
337.37
Structure
Simcomp
Remark
Same as: C13670
Efficacy
Antiepileptic, AMPA receptor antagonist
Target
GRIA [HSA:2890 2891 2892 2893] [KO:K05197 K05198 K05199 K05200]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04724  Glutamatergic synapse
hsa04728  Dopaminergic synapse
Structure map
map07117  Benzodiazepine family
Brite
Target-based classification of drugs [BR:br08310]
 Ion channels
  Ligand-gated ion channels
   Glutamate (ionotropic), non-NMDA
    GRIA
     D02696  Talampanel (INN)
Other DBs
CAS: 161832-65-1
PubChem: 17396863
ChEBI: 34992
LigandBox: D02696
LinkDB
KCF data

ATOM        25
            1   C8y C    21.4109  -15.2870
            2   C1x C    22.6746  -14.6939
            3   C1y C    23.9342  -15.3064
            4   N1y N    24.2367  -16.6632
            5   C8y C    21.0920  -16.6593
            6   N2x N    23.3645  -17.7615
            7   C2y C    21.9631  -17.7557
            8   C8x C    20.3884  -14.3307
            9   C8y C    19.0491  -14.7381
            10  C8y C    18.7302  -16.1104
            11  C8x C    19.7527  -17.0666
            12  C8y C    21.3457  -19.0275
            13  C8x C    19.9429  -19.0212
            14  C8x C    19.2363  -20.2297
            15  C8y C    19.9296  -21.4460
            16  C8x C    21.3295  -21.4536
            17  C8x C    22.0361  -20.2451
            18  O2x O    17.8424  -14.0106
            19  C1x C    16.7777  -14.9335
            20  O2x O    17.3264  -16.2311
            21  N1a N    19.2398  -22.6258
            22  C1a C    25.0246  -14.4447
            23  C5a C    25.4320  -17.3593
            24  C1a C    26.6445  -16.6593
            25  O5a O    25.4294  -18.7592
BOND        28
            1     3   4 1
            2     1   5 2
            3     4   6 1
            4     2   3 1
            5     5   7 1
            6     1   2 1
            7     6   7 2
            8     1   8 1
            9     8   9 2
            10    9  10 1
            11   10  11 2
            12    5  11 1
            13    7  12 1
            14   12  13 2
            15   13  14 1
            16   14  15 2
            17   15  16 1
            18   16  17 2
            19   12  17 1
            20    9  18 1
            21   18  19 1
            22   19  20 1
            23   10  20 1
            24   15  21 1
            25    3  22 1 #Up
            26    4  23 1
            27   23  24 1
            28   23  25 2

» Japanese version   » Back

DBGET integrated database retrieval system