KEGG   DRUG: Azimilide dihydrochloride
Entry
D03037                      Drug                                   

Name
Azimilide dihydrochloride (USAN)
Formula
C23H28ClN5O3. 2HCl
Exact mass
529.1414
Mol weight
530.875
Structure
Simcomp
Class
Cardiovascular agent
 DG01653  Antiarrhythmics
  DG01648  Class III antiarrhythmic agent
Efficacy
Antiarrhythmic, Potassium channel blocker
Target
KCNH2 [HSA:3757] [KO:K04905]
KCNQ1 [HSA:3784] [KO:K04926]
Interaction
Structure map
map07037  Antiarrhythmic drugs
map07232  Potassium channel blocking and opening drugs
Brite
Target-based classification of drugs [BR:br08310]
 Ion channels
  Voltage-gated ion channels
   Potassium channels
    KCNH2
     D03037  Azimilide dihydrochloride (USAN)
    KCNQ1
     D03037  Azimilide dihydrochloride (USAN)
Other DBs
CAS: 149888-94-8
PubChem: 17397192
ChEMBL: CHEMBL3140370
LigandBox: D03037
NIKKAJI: J567.110H
LinkDB
KCF data

ATOM        34
            1   X   Cl   38.8859  -20.8431
            2   N1y N    28.7919  -18.9141
            3   C5x C    30.1937  -18.9141
            4   N1y N    30.6268  -17.5810
            5   C5x C    29.4928  -16.7570
            6   C1x C    28.3588  -17.5810
            7   O5x O    29.4928  -15.3397
            8   O5x O    31.0176  -20.0481
            9   N2b N    27.9680  -20.0481
            10  C2b C    26.5663  -20.0481
            11  C8y C    25.8666  -21.2598
            12  C1b C    33.0547  -17.5810
            13  C1b C    31.8408  -16.8801
            14  C1b C    35.4827  -17.5810
            15  C1b C    34.2687  -16.8801
            16  N1y N    36.6714  -16.8943
            17  C1x C    37.8577  -17.5790
            18  C1x C    39.0715  -16.8779
            19  N1y N    39.0713  -15.4761
            20  C1x C    37.8851  -14.7915
            21  C1x C    36.6711  -15.4926
            22  C1a C    40.3010  -14.7657
            23  O2x O    24.4468  -21.2558
            24  C8y C    24.0037  -22.6008
            25  C8x C    25.1459  -23.4378
            26  C8x C    26.2949  -22.6102
            27  C8y C    22.6020  -22.6008
            28  C8x C    21.9189  -21.4174
            29  C8x C    20.5172  -21.4172
            30  C8y C    19.8162  -22.6311
            31  C8x C    20.4992  -23.8145
            32  C8x C    21.9010  -23.8146
            33  X   Cl   18.4191  -22.6310
            34  X   Cl   38.8859  -20.8431
BOND        35
            1     2   3 1
            2     3   4 1
            3     4   5 1
            4     5   6 1
            5     2   6 1
            6     5   7 2
            7     3   8 2
            8     2   9 1
            9     9  10 2
            10   10  11 1
            11   12  13 1
            12    4  13 1
            13   14  15 1
            14   12  15 1
            15   14  16 1
            16   16  17 1
            17   17  18 1
            18   18  19 1
            19   19  20 1
            20   20  21 1
            21   16  21 1
            22   19  22 1
            23   11  23 1
            24   23  24 1
            25   24  25 2
            26   25  26 1
            27   11  26 2
            28   24  27 1
            29   27  28 2
            30   28  29 1
            31   29  30 2
            32   30  31 1
            33   31  32 2
            34   27  32 1
            35   30  33 1
BRACKET     1    37.1700  -21.7700   37.1700  -19.8800
            1    39.6900  -19.8800   39.6900  -21.7700
            1  2
 ORIGINAL  1    1
 REPEAT    1   34

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