KEGG   DRUG: Carperitide
Entry
D03328                      Drug                                   

Name
Carperitide (USAN/INN);
Carperitide (genetical recombination) (JAN);
Hanp (TN)
Formula
C127H203N45O39S3
Exact mass
3078.4447
Mol weight
3080.4438
Sequence
Ser Leu Arg Arg Ser Ser Cys Phe Gly Gly Arg Met Asp Arg Ile Gly
Ala Gln Ser Gly Leu Gly Cys Asn Ser Phe Arg Tyr
(Disulfide bridge: 7-23)
  Type
Peptide
Remark
Therapeutic category: 2179
Product: D03328<JP>
Efficacy
Vasodilator, Atrial natriuretic peptide receptor agonist
Comment
Recombinant of human alpha atrial natriuretic polypeptide (ANP) [HSA:4878]
Target
NPR1 [HSA:4881] [KO:K12323]
  Pathway
hsa04022  cGMP-PKG signaling pathway
hsa04024  cAMP signaling pathway
hsa04270  Vascular smooth muscle contraction
Interaction
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   217  Vasodilators
    2179  Others
     D03328  Carperitide (USAN/INN); Carperitide (genetical recombination) (JAN)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Lyases (EC4)
   Phosphorus-oxygen lyases
    NPR1
     D03328  Carperitide (USAN/INN) <JP>
Other DBs
CAS: 89213-87-6
PubChem: 17397478
NIKKAJI: J265.257I
LinkDB

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