KEGG   DRUG: Teriparatide acetate
Entry
D03358                      Drug                                   

Name
Teriparatide acetate (JAN);
Human PHT (TN)
Formula
C181H291N55O51S2. (C2H4O2)5
Exact mass
4415.2366
Mol weight
4417.9749
Sequence
Ser Val Ser Glu Ile Gln Leu Met His Asn Leu Gly Lys His Leu Asn
Ser Met Glu Arg Val Glu Trp Leu Arg Lys Lys Leu Gln Asp Val His
Asn Phe-OH
  Type
Peptide
Class
Other
 DG01661  Parathyroid hormone
Remark
Therapeutic category: 2439 7223
ATC code: H05AA02
Chemical structure group: DG00512
Product (DG00512): D06078<JP/US> D03358<JP>
Efficacy
Diagnostic (parathyroid function), Osteoporosis agent, Parathyroid hormone receptor agonist
Target
PTH1R [HSA:5745] [KO:K04585]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04928  Parathyroid hormone synthesis, secretion and action
hsa04961  Endocrine and other factor-regulated calcium reabsorption
Interaction
Structure map
map07047  Osteoporosis drugs
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
  H05 CALCIUM HOMEOSTASIS
   H05A PARATHYROID HORMONES AND ANALOGUES
    H05AA Parathyroid hormones and analogues
     H05AA02 Teriparatide
      D03358  Teriparatide acetate (JAN) <JP>
USP drug classification [BR:br08302]
 Metabolic Bone Disease Agents
  Calcium Regulating Hormones
   Teriparatide
    D03358  Teriparatide acetate (JAN)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  24  Hormones
   243  Thyroid and parathyroid hormone preparations
    2439  Others
     D03358  Teriparatide acetate (JAN)
 7  Agents not mainly for therapeutic purpose
  72  Intracorporeal diagnostic agents
   722  Various function testing reagents
    7223  Diagnostic reagents for endocrine function
     D03358  Teriparatide acetate (JAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Secretin receptor family
   Parathyroid hormone
    PTH1R
     D03358  Teriparatide acetate (JAN) <JP>
Other DBs
PubChem: 17397507
LinkDB

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