KEGG   DRUG: Clofilium phosphate
Entry
D03547                      Drug                                   

Name
Clofilium phosphate (USAN/INN)
Formula
C21H37ClN. H2PO4
Exact mass
435.2305
Mol weight
435.9654
Structure
Simcomp
Efficacy
Antiarrhythmic, Potassium channel blocker
Target
KCND [HSA:3750 3751 3752] [KO:K04891 K04892 K04893]
KCNH1 [HSA:3756] [KO:K04904]
KCNH2 [HSA:3757] [KO:K04905]
KCNT2 (SLICK) [HSA:343450] [KO:K04947]
Structure map
map07037  Antiarrhythmic drugs
map07232  Potassium channel blocking and opening drugs
Brite
Target-based classification of drugs [BR:br08310]
 Ion channels
  Voltage-gated ion channels
   Potassium channels
    KCND
     D03547  Clofilium phosphate (USAN/INN)
    KCNH1
     D03547  Clofilium phosphate (USAN/INN)
    KCNH2
     D03547  Clofilium phosphate (USAN/INN)
    KCNT2 (SLICK)
     D03547  Clofilium phosphate (USAN/INN)
Other DBs
CAS: 68379-03-3
PubChem: 17397670
ChEMBL: CHEMBL32510
LigandBox: D03547
NIKKAJI: J395.800K
LinkDB
KCF data

ATOM        28
            1   P1b P    27.2300  -12.6700
            2   O1c O    27.2300  -11.2700
            3   O1c O    27.2300  -14.0700
            4   O1c O    28.6766  -12.6700 #-
            5   O1c O    25.8766  -12.6700
            6   C8y C    18.9445  -14.0042
            7   C8x C    18.9445  -15.4067
            8   C8x C    20.1592  -16.1080
            9   C8y C    21.3738  -15.4067
            10  C8x C    21.3738  -14.0042
            11  C8x C    20.1592  -13.3029
            12  C1b C    17.7300  -13.3029
            13  C1b C    16.5152  -14.0042
            14  C1b C    15.3007  -13.3029
            15  C1b C    14.0860  -14.0042
            16  N1d N    12.8714  -13.3029 #+
            17  C1b C    11.6567  -14.0042
            18  C1b C    10.4422  -13.3029
            19  C1b C     9.2274  -14.0042
            20  C1b C     8.0129  -13.3029
            21  C1b C     6.7981  -14.0042
            22  C1b C     5.5836  -13.3029
            23  C1a C     4.3689  -14.0042
            24  X   Cl   22.5912  -16.1080
            25  C1b C    14.0562  -12.6188
            26  C1b C    11.6481  -12.5967
            27  C1a C    11.6440  -11.2233
            28  C1a C    14.0413  -11.2233
BOND        27
            1     1   3 1
            2     1   4 1
            3     1   5 1
            4     1   2 2
            5     6   7 2
            6     7   8 1
            7     8   9 2
            8     9  10 1
            9    10  11 2
            10    6  11 1
            11    6  12 1
            12   12  13 1
            13   13  14 1
            14   14  15 1
            15   15  16 1
            16   16  17 1
            17   17  18 1
            18   18  19 1
            19   19  20 1
            20   20  21 1
            21   21  22 1
            22   22  23 1
            23    9  24 1
            24   16  25 1
            25   16  26 1
            26   26  27 1
            27   25  28 1

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