KEGG   DRUG: Dexmethylphenidate hydrochloride
Entry
D03721                      Drug                                   

Name
Dexmethylphenidate hydrochloride (USAN);
Focalin (TN)
Product
  Generic
Formula
C14H19NO2. HCl
Exact mass
269.1183
Mol weight
269.7671
Structure
Simcomp
Class
Neuropsychiatric agent
 DG01970  Agents for ADHD
Remark
ATC code: N06BA11
Chemical structure group: DG00972
Product (DG00972): D03721<US>
Efficacy
Stimulant (central)
  Disease
Attention deficit hyperactivity disorder [DS:H01895]
Comment
Treatment of attention deficit/ hyperactivity disorder (ADHD)
Target
SLC6A2 (NAT1) [HSA:6530] [KO:K05035]
SLC6A3 (DAT1) [HSA:6531] [KO:K05036]
SLC6A4 (HTT) [HSA:6532] [KO:K05037]
  Pathway
hsa04721  Synaptic vesicle cycle
hsa04726  Serotonergic synapse
hsa04728  Dopaminergic synapse
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N06 PSYCHOANALEPTICS
   N06B PSYCHOSTIMULANTS, AGENTS USED FOR ADHD AND NOOTROPICS
    N06BA Centrally acting sympathomimetics
     N06BA11 Dexmethylphenidate
      D03721  Dexmethylphenidate hydrochloride (USAN) <US>
USP drug classification [BR:br08302]
 Central Nervous System Agents
  Attention Deficit Hyperactivity Disorder Agents, Non-amphetamines
   Dexmethylphenidate
    D03721  Dexmethylphenidate hydrochloride (USAN)
Target-based classification of drugs [BR:br08310]
 Transporters
  Solute carrier family
   SLC6
    SLC6A2 (NAT1)
     D03721  Dexmethylphenidate hydrochloride (USAN) <US>
    SLC6A3 (DAT1)
     D03721  Dexmethylphenidate hydrochloride (USAN) <US>
    SLC6A4 (HTT)
     D03721  Dexmethylphenidate hydrochloride (USAN) <US>
Other DBs
CAS: 19262-68-1
PubChem: 17397812
ChEMBL: CHEMBL904
LigandBox: D03721
LinkDB
KCF data

ATOM        18
            1   C1c C    32.6431  -17.9493
            2   C1y C    31.4433  -17.2330
            3   C7a C    33.8664  -17.2563
            4   C1x C    30.2259  -17.9203
            5   N1x N    31.4607  -15.8350
            6   O7a O    33.8838  -15.8583
            7   O6a O    35.0721  -17.9726
            8   C1x C    29.0202  -17.2096
            9   C1x C    30.2549  -15.1185
            10  C1a C    35.1012  -15.1710
            11  C1x C    29.0318  -15.8058
            12  C8y C    32.6314  -19.3473
            13  C8x C    31.4140  -20.0346
            14  C8x C    33.8372  -20.0579
            15  C8x C    31.4024  -21.4383
            16  C8x C    33.8198  -21.4559
            17  C8x C    32.5965  -22.1489
            18  X   Cl   39.0873  -18.1277
BOND        18
            1     1   2 1
            2     1   3 1
            3     2   4 1
            4     2   5 1
            5     3   6 1
            6     3   7 2
            7     4   8 1
            8     5   9 1
            9     6  10 1
            10    8  11 1
            11    9  11 1
            12   12  13 2
            13   12  14 1
            14   13  15 1
            15   14  16 2
            16   15  17 2
            17   16  17 1
            18    1  12 1 #Down

» Japanese version   » Back

DBGET integrated database retrieval system