KEGG   DRUG: Oblimersen sodium
Entry
D05216                      Drug                                   

Name
Oblimersen sodium (USAN);
Genasense (TN)
Formula
C172H204N62O91P17S17. 17Na
Exact mass
6054.2294
Mol weight
6058.306
Remark
ATC code: L01XX36
Chemical structure group: DG00728
Efficacy
Antineoplastic, Translation inhibitor, Bcl-2 inhibitor
Comment
Antisense oligonucleotide
Treatment of cancer and rheumatological diseases
Target
BCL2 [HSA:596] [KO:K02161] (mRNA)
  Pathway
hsa04210  Apoptosis
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L01 ANTINEOPLASTIC AGENTS
   L01X OTHER ANTINEOPLASTIC AGENTS
    L01XX Other antineoplastic agents
     L01XX36 Oblimersen
      D05216  Oblimersen sodium (USAN)
Target-based classification of drugs [BR:br08310]
 Not elsewhere classified
  Cellular process
   Apoptosis
    BCL2
     D05216  Oblimersen sodium (USAN)
Other DBs
CAS: 190977-41-4
PubChem: 47206935
LinkDB

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