KEGG   DRUG: Pamatolol sulfate
Entry
D05345                      Drug                                   

Name
Pamatolol sulfate (USAN)
Formula
(C16H26N2O4)2. H2SO4
Exact mass
718.3459
Mol weight
718.8558
Structure
Class
Cardiovascular agent
 DG01466  Adrenergic receptor antagonist
  DG01464  beta-Adrenergic receptor antagonist
   DG01461  beta1-Adrenergic receptor antagonist
   DG01462  beta2-Adrenergic receptor antagonist
   DG01463  beta3-Adrenergic receptor antagonist
Efficacy
Antiarrhythmic, beta-Adrenergic receptor antagonist
Target
ADRB [HSA:153 154 155] [KO:K04141 K04142 K04143]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04970  Salivary secretion
Interaction
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    ADRB
     D05345  Pamatolol sulfate (USAN)
Other DBs
CAS: 59954-01-7
PubChem: 47207031
ChEMBL: CHEMBL3989491
LigandBox: D05345
NIKKAJI: J365.023E
LinkDB
KCF data

ATOM        49
            1   S4a S    35.4900  -26.3200
            2   O1d O    35.4900  -24.9200
            3   O1d O    35.4900  -27.7200
            4   O1d O    34.0200  -26.3200
            5   O1d O    36.8900  -26.3200
            6   O2a O    22.2600  -21.6300
            7   C1b C    23.5200  -20.9300
            8   C1c C    24.7100  -21.6300
            9   C1b C    25.9000  -20.9300
            10  N1b N    27.0900  -21.6300
            11  C1c C    28.2800  -20.9300
            12  O1a O    24.7100  -23.0300
            13  C1a C    29.4700  -21.6300
            14  C1a C    28.2800  -19.5300
            15  C8y C    22.2428  -23.0299
            16  C8x C    21.0349  -23.7076
            17  C8x C    21.0178  -25.1075
            18  C8y C    22.2216  -25.8223
            19  C8x C    23.4294  -25.1446
            20  C8x C    23.4465  -23.7447
            21  C1b C    22.2045  -27.2299
            22  C1b C    20.9727  -27.9214
            23  N1b N    19.7928  -27.2210
            24  C7a C    18.5813  -27.9011
            25  O7a O    17.3677  -27.1803
            26  C1a C    16.1496  -27.8636
            27  O6a O    18.5645  -29.3299
            28  O2a O    22.2600  -21.6300
            29  C1b C    23.5200  -20.9300
            30  C1c C    24.7100  -21.6300
            31  C1b C    25.9000  -20.9300
            32  N1b N    27.0900  -21.6300
            33  C1c C    28.2800  -20.9300
            34  C1a C    29.4700  -21.6300
            35  C1a C    28.2800  -19.5300
            36  O1a O    24.7100  -23.0300
            37  C8y C    22.2428  -23.0299
            38  C8x C    21.0349  -23.7076
            39  C8x C    21.0178  -25.1075
            40  C8y C    22.2216  -25.8223
            41  C8x C    23.4294  -25.1446
            42  C8x C    23.4465  -23.7447
            43  C1b C    22.2045  -27.2299
            44  C1b C    20.9727  -27.9214
            45  N1b N    19.7928  -27.2210
            46  C7a C    18.5813  -27.9011
            47  O7a O    17.3677  -27.1803
            48  C1a C    16.1496  -27.8636
            49  O6a O    18.5645  -29.3299
BOND        48
            1     1   2 2
            2     1   3 2
            3     1   4 1
            4     1   5 1
            5     6   7 1
            6     7   8 1
            7     8   9 1
            8     9  10 1
            9    10  11 1
            10    8  12 1
            11   11  13 1
            12   11  14 1
            13    6  15 1
            14   15  16 2
            15   16  17 1
            16   17  18 2
            17   18  19 1
            18   19  20 2
            19   15  20 1
            20   18  21 1
            21   21  22 1
            22   22  23 1
            23   23  24 1
            24   24  25 1
            25   25  26 1
            26   24  27 2
            27   28  29 1
            28   29  30 1
            29   30  31 1
            30   31  32 1
            31   32  33 1
            32   30  36 1
            33   33  34 1
            34   33  35 1
            35   28  37 1
            36   37  38 2
            37   38  39 1
            38   39  40 2
            39   40  41 1
            40   41  42 2
            41   37  42 1
            42   40  43 1
            43   43  44 1
            44   44  45 1
            45   45  46 1
            46   46  47 1
            47   47  48 1
            48   46  49 2
BRACKET     1    14.2800  -30.1000   14.2800  -17.9900
            1    31.2900  -17.9900   31.2900  -30.1000
            1  2
 ORIGINAL  1    6   7   8   9  10  11  13  14  12  15  16  17  18  19  20  21
            1   22  23  24  25  26  27
 REPEAT    1   28  29  30  31  32  33  34  35  36  37  38  39  40  41  42  43
            1   44  45  46  47  48  49

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