KEGG   DRUG: Radafaxine hydrochloride
Entry
D05692                      Drug                                   

Name
Radafaxine hydrochloride (USAN)
Formula
C13H18ClNO2. HCl
Exact mass
291.0793
Mol weight
292.2015
Structure
Simcomp
Efficacy
Antianxiety, Antidepressant, Noradrenaline and dopamine reuptake inhibitor
Target
SLC6A2 (NAT1) [HSA:6530] [KO:K05035]
SLC6A3 (DAT1) [HSA:6531] [KO:K05036]
  Pathway
hsa04721  Synaptic vesicle cycle
hsa04728  Dopaminergic synapse
Brite
Target-based classification of drugs [BR:br08310]
 Transporters
  Solute carrier family
   SLC6
    SLC6A2 (NAT1)
     D05692  Radafaxine hydrochloride (USAN)
    SLC6A3 (DAT1)
     D05692  Radafaxine hydrochloride (USAN)
Other DBs
CAS: 106083-71-0
PubChem: 47207353
ChEMBL: CHEMBL2107365
LigandBox: D05692
LinkDB
KCF data

ATOM        18
            1   X   Cl   17.1072  -20.4407
            2   C1z C    12.8800  -22.6100
            3   C1y C    12.8800  -24.0100
            4   N1x N    14.0924  -24.7100
            5   C1z C    15.3049  -24.0100
            6   C1x C    15.3049  -22.6100
            7   O2x O    14.0924  -21.9100
            8   O1a O    12.8800  -21.2100
            9   C1a C    11.6676  -24.7100
            10  C8y C    11.4800  -22.6100
            11  C8x C    10.7800  -21.3976
            12  C8y C     9.3800  -21.3976
            13  C8x C     8.6800  -22.6100
            14  C8x C     9.3800  -23.8224
            15  C8x C    10.7800  -23.8224
            16  X   Cl    8.6896  -20.2021
            17  C1a C    16.5360  -24.7210
            18  C1a C    16.5361  -23.2991
BOND        18
            1     2   3 1
            2     3   4 1
            3     4   5 1
            4     5   6 1
            5     6   7 1
            6     2   7 1
            7     2   8 1 #Up
            8     3   9 1 #Up
            9     2  10 1 #Down
            10   10  11 2
            11   11  12 1
            12   12  13 2
            13   13  14 1
            14   14  15 2
            15   10  15 1
            16   12  16 1
            17    5  17 1
            18    5  18 1

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