KEGG   DRUG: Sargramostim
Entry
D05803                      Drug                                   
Name
Sargramostim (USP/INN);
Sargramostim (genetical recombination) (JAN);
Leukine (TN);
Sargmalin (TN)
Product
Class
Immunological agent
 DG01753  Colony stimulating factor
  DG01782  Granulocyte macrophage colony-stimulating factors (GM-CSF)
Remark
Therapeutic category: 2290
ATC code: L03AA09
Product: D05803<JP/US>
Efficacy
Antineutropenic, Hematopoietic stimulant, Granulocyte-macrophage colony stimulating factor (GM-CSF)
  Disease
Acute myelogenous leukemia [DS:H00003]
Comment
Recombinant GM-CSF [HSA:1437] [KO:K05427]
Target
CSF2RA (GMCSFR, CD116) [HSA:1438] [KO:K05066]
  Pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa04630  JAK-STAT signaling pathway
hsa04640  Hematopoietic cell lineage
hsa05200  Pathways in cancer
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L03 IMMUNOSTIMULANTS
   L03A IMMUNOSTIMULANTS
    L03AA Colony stimulating factors
     L03AA09 Sargramostim
      D05803  Sargramostim (USP/INN) <US>
USP drug classification [BR:br08302]
 Immunological Agents
  Immunostimulants
   Colony-stimulating Factors
    Sargramostim
     D05803  Sargramostim (USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  22  Respiratory organ agents
   229  Miscellaneous
    2290  Miscellaneous
     D05803  Sargramostim (USP/INN); Sargramostim (genetical recombination) (JAN)
Drug groups [BR:br08330]
 Immunological agent
  DG01753  Colony stimulating factor
   DG01782  Granulocyte macrophage colony-stimulating factors (GM-CSF)
    D05803  Sargramostim
Drug classes [BR:br08332]
 Immunological agent
  DG01753  Colony stimulating factor
   D05803  Sargramostim
Target-based classification of drugs [BR:br08310]
 Cytokines and receptors
  Cytokine receptors
   CSF and other factor receptors
    CSF2RA (GMCSFR, CD116)
     D05803  Sargramostim (USP/INN) <JP/US>
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D05803
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D05803
Other DBs
CAS: 123774-72-1
PubChem: 47207464
LinkDB

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