KEGG   DRUG: Tiazofurin
Entry
D06130                      Drug                                   

Name
Tiazofurin (USAN);
Tiazofurine (INN)
Formula
C9H12N2O5S
Exact mass
260.0467
Mol weight
260.267
Structure
Remark
Same as: C22196
ATC code: L01XX18
Efficacy
Antineoplastic, Antimetabolite
Target
IMPDH [HSA:3614 3615] [KO:K00088]
  Pathway
hsa00230  Purine metabolism
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L01 ANTINEOPLASTIC AGENTS
   L01X OTHER ANTINEOPLASTIC AGENTS
    L01XX Other antineoplastic agents
     L01XX18 Tiazofurine
      D06130  Tiazofurin (USAN)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Oxidoreductases (EC1)
   Dehydrogenases
    IMPDH
     D06130  Tiazofurin (USAN)
Other DBs
CAS: 60084-10-8
PubChem: 47207788
ChEBI: 90239
ChEMBL: CHEMBL108358
PDB-CCD: TIZ[PDBj]
LigandBox: D06130
NIKKAJI: J33.073F
LinkDB
KCF data

ATOM        17
            1   C1y C    12.6700  -18.5500
            2   C1y C    14.0700  -18.5500
            3   C1y C    14.5026  -17.2185
            4   O2x O    13.3700  -16.3956
            5   C1y C    12.2374  -17.2185
            6   C1b C    10.9178  -16.7897
            7   C8y C    15.8222  -16.7897
            8   O1a O    11.8471  -19.6826
            9   O1a O    14.8929  -19.6826
            10  O1a O     9.8735  -17.7299
            11  N5x N    16.9583  -17.6150
            12  C8y C    18.0943  -16.7896
            13  C8x C    17.6603  -15.4542
            14  S2x S    16.2561  -15.4542
            15  C5a C    19.3975  -17.2135
            16  N1a N    20.4308  -16.2837
            17  O5a O    19.6893  -18.5876
BOND        18
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     1   5 1
            6     5   6 1 #Up
            7     3   7 1 #Up
            8     1   8 1 #Down
            9     2   9 1 #Down
            10    6  10 1
            11    7  11 2
            12   11  12 1
            13   12  13 2
            14   13  14 1
            15    7  14 1
            16   12  15 1
            17   15  16 1
            18   15  17 2

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