KEGG   DRUG: Triciribine phosphate
Entry
D06221                      Drug                                   

Name
Triciribine phosphate (USAN)
Formula
C13H17N6O7P
Exact mass
400.0896
Mol weight
400.2838
Structure
Class
Antineoplastic
 DG01958  Nucleic acid derivative, antineoplastic
  DG01439  Arabinofuranosyl type antineoplastic
 DG01439  Arabinofuranosyl type antineoplastic
 DG02018  Antimetabolite
  DG01958  Nucleic acid derivative, antineoplastic
   DG01439  Arabinofuranosyl type antineoplastic
Efficacy
Antineoplastic, Antimetabolite, AKT serine/threonine kinase inhibitor
Target
AKT (PKB) [HSA:207 208 10000] [KO:K04456]
  Pathway
hsa04150  mTOR signaling pathway
hsa04151  PI3K-Akt signaling pathway
Interaction
Brite
Target-based classification of drugs [BR:br08310]
 Protein kinases
  Serine/threonine kinases
   AGC group
    AKT (PKB)
     D06221  Triciribine phosphate (USAN)
Other DBs
CAS: 61966-08-3
PubChem: 47207879
ChEMBL: CHEMBL462018
PDB-CCD: TR5[PDBj]
LigandBox: D06221
NIKKAJI: J69.483E
LinkDB
KCF data

ATOM        27
            1   C1y C     8.6800  -24.5700
            2   C1y C    10.0800  -24.5700
            3   C1y C    10.5000  -23.2400
            4   O2x O     9.3800  -22.4700
            5   C1y C     8.2600  -23.2400
            6   N4y N    11.6900  -22.5400
            7   C1b C     7.0700  -22.5400
            8   O2b O     5.8100  -23.2400
            9   O1a O     7.8400  -25.6900
            10  O1a O    10.9200  -25.6900
            11  N5x N    12.6000  -24.9200
            12  C8x C    13.8600  -25.6200
            13  N5x N    15.0500  -24.9200
            14  C8y C    15.0500  -23.5200
            15  C8y C    13.8600  -22.8200
            16  C8y C    12.6000  -23.5200
            17  N4y N    16.2400  -22.8200
            18  N5x N    16.2400  -21.4200
            19  C8y C    15.0500  -20.7200
            20  C8y C    13.8600  -21.4200
            21  C8x C    12.3900  -21.2100
            22  C1a C    17.4553  -23.5151
            23  N1a N    15.0500  -19.3200
            24  P1b P     4.4100  -23.2400
            25  O1c O     4.4100  -21.8400
            26  O1c O     3.0100  -23.2400
            27  O1c O     4.4100  -24.6400
BOND        30
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     1   5 1
            6     3   6 1 #Up
            7     5   7 1 #Up
            8     7   8 1
            9     1   9 1 #Down
            10    2  10 1 #Down
            11   11  12 2
            12   12  13 1
            13   13  14 2
            14   14  15 1
            15   15  16 2
            16   11  16 1
            17   14  17 1
            18   17  18 1
            19   18  19 2
            20   19  20 1
            21   15  20 1
            22   20  21 2
            23   21   6 1
            24   16   6 1
            25   17  22 1
            26   19  23 1
            27    8  24 1
            28   24  25 2
            29   24  26 1
            30   24  27 1

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